Avatrombopag
Avatrombopag, sold under the brand name Doptelet, is a medication that used for certain conditions.lead to thrombocytopenia (low platelets) such as thrombocytopenia associated with chronic liver disease. Reference standards of Avatrombopag API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[catalogue_number] => PA 01 2991000
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[weight] => 284.7
[form] => C12H13ClN2O4
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6-(4-Carboxypiperidin-1-yl)-5-chloronicotinic Acid
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[pname] => 1-(5-((4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic Acid
[catalogue_number] => PA 01 2991001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 728.55
[form] => C29H33BrCl2N6O3S2
[cas] => NA
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1-(5-((4-(5-Bromo-4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic Acid
Catalogue No.:PA 01 2991001
Molecular Formula : C29H33BrCl2N6O3S2
Molecular Weight : 728.55
stdClass Object
(
[pname] => 5-Bromo-4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine
[catalogue_number] => PA 01 2991002
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[chemical_name] =>
[weight] => 374.49
[form] => C7H3Br2ClN2S2
[cas] => 2401867-89-6
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5-Bromo-4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine
Catalogue No.:PA 01 2991002
Molecular Formula : C7H3Br2ClN2S2
Molecular Weight : 374.49
stdClass Object
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[pname] => 4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine
[catalogue_number] => PA 01 2991003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 295.6
[form] => C7H4BrClN2S2
[cas] => 1534575-19-3
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4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine
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[pname] => 5-Bromo-4-(thiophen-2-yl)thiazol-2-amine
[catalogue_number] => PA 01 2991004
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[chemical_name] =>
[weight] => 261.16
[form] => C7H5BrN2S2
[cas] => 81216-84-4
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5-Bromo-4-(thiophen-2-yl)thiazol-2-amine
Catalogue No.:PA 01 2991004
Molecular Formula : C7H5BrN2S2
Molecular Weight : 261.16
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[catalogue_number] => PA 01 2991005
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[weight] => 295.6
[form] => C7H4BrClN2S2
[cas] => 1268118-96-2
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5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine
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[pname] => 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine
[catalogue_number] => PA 01 2991006
[category_ids] => ,75,76,78,70,82,123,81,
[chemical_name] =>
[weight] => 216.7
[form] => C7H5ClN2S2
[cas] => 123971-45-9
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4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine
stdClass Object
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[pname] => 4-(Thiophen-2-yl)thiazol-2-amine
[catalogue_number] => PA 01 2991007
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[chemical_name] =>
[weight] => 182.26
[form] => C7H6N2S2
[cas] => 28989-50-6
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4-(Thiophen-2-yl)thiazol-2-amine
Catalogue No.:PA 01 2991007
Molecular Formula : C7H6N2S2
Molecular Weight : 182.26
stdClass Object
(
[pname] => 4-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-cyclohexylpiperazine 1-oxide
[catalogue_number] => PA 01 2991013
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 665.65
[form] => C29H34Cl2N6O4S2
[cas] => 2681355-40-6
[pslug] => 2681355-40-6-4-2-6-4-carboxypiperidin-1-yl-5-chloronicotinamido-4-4-chlorothiophen-2-yl-thiazol-5-yl-1-cyclohexylpiperazine-1-oxide-pa012991013
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4-(2-(6-(4-Carboxypiperidin-1-yl)-5-chloronicotinamido)-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-1-cyclohexylpiperazine 1-oxide
Catalogue No.:PA 01 2991013
Molecular Formula : C29H34Cl2N6O4S2
Molecular Weight : 665.65
stdClass Object
(
[pname] => 5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(dimethylamino)nicotinamide
[catalogue_number] => PA 01 2991008
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[chemical_name] =>
[weight] => 565.58
[form] => C25H30Cl2N6OS2
[cas] => 2626934-45-8
[pslug] => 2626934-45-8-5-chloro-n-4-4-chlorothiophen-2-yl-5-4-cyclohexylpiperazin-1-yl-thiazol-2-yl-6-dimethylamino-nicotinamide-pa012991008
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5-Chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(dimethylamino)nicotinamide
Catalogue No.:PA 01 2991008
Molecular Formula : C25H30Cl2N6OS2
Molecular Weight : 565.58
stdClass Object
(
[pname] => 4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
[catalogue_number] => PA 01 2991009
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[chemical_name] =>
[weight] => 382.97
[form] => C17H23ClN4S2
[cas] => 570407-64-6
[pslug] => 570407-64-6-4-4-chlorothiophen-2-yl-5-4-cyclohexylpiperazin-1-yl-thiazol-2-amine-pa012991009
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4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
Catalogue No.:PA 01 2991009
Molecular Formula : C17H23ClN4S2
Molecular Weight : 382.97
stdClass Object
(
[pname] => Avatrombopag Ester Impurity
[catalogue_number] => PA 01 2991010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 677.7
[form] => C31H38Cl2N6O3S2
[cas] => 570403-14-4
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Avatrombopag Ester Impurity
stdClass Object
(
[pname] => Ethyl 1-ethylpiperidine-4-carboxylate
[catalogue_number] => PA 01 2991011
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 185.27
[form] => C10H19NO2
[cas] => 24252-38-8
[pslug] => 24252-38-8-ethyl-1-ethylpiperidine-4-carboxylate-pa012991011
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Ethyl 1-ethylpiperidine-4-carboxylate
Catalogue No.:PA 01 2991011
Molecular Formula : C10H19NO2
Molecular Weight : 185.27
stdClass Object
(
[pname] => 5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide
[catalogue_number] => PA 01 2991012
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 556.95
[form] => C23H24Cl3N5OS2
[cas] => 570403-04-2
[pslug] => 570403-04-2-5-6-dichloro-n-4-4-chlorothiophen-2-yl-5-4-cyclohexylpiperazin-1-yl-thiazol-2-yl-nicotinamide-pa012991012
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5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide
Catalogue No.:PA 01 2991012
Molecular Formula : C23H24Cl3N5OS2
Molecular Weight : 556.95
stdClass Object
(
[pname] => 1-(3-Chloro-5-((5-(4-cyclohexylpiperazin-1-yl)-4-(4,5-dichlorothiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid
[catalogue_number] => PA 01 2991014
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 684.09
[form] => C29H33Cl3N6O3S2
[cas] => NA
[pslug] => 1-3-chloro-5-5-4-cyclohexylpiperazin-1-yl-4-4-5-dichlorothiophen-2-yl-thiazol-2-yl-carbamoyl-pyridin-2-yl-piperidine-4-carboxylic-acid-pa012991014
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1-(3-Chloro-5-((5-(4-cyclohexylpiperazin-1-yl)-4-(4,5-dichlorothiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid
Catalogue No.:PA 01 2991014
Molecular Formula : C29H33Cl3N6O3S2
Molecular Weight : 684.09
stdClass Object
(
[pname] => 4-(4-Chlorothiophen-2-yl)thiazol-2-amine
[catalogue_number] => PA 01 2991015
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 216.7
[form] => C7H5ClN2S2
[cas] => 570407-10-2
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4-(4-Chlorothiophen-2-yl)thiazol-2-amine
stdClass Object
(
[pname] => 4-(3-Chlorothiophen-2-yl)thiazol-2-amine
[catalogue_number] => PA 01 2991016
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[chemical_name] =>
[weight] => 216.7
[form] => C7H5ClN2S2
[cas] => 339114-12-4
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4-(3-Chlorothiophen-2-yl)thiazol-2-amine
stdClass Object
(
[pname] => Avatrombopag Diamide Impurity
[catalogue_number] => PA 01 2991017
[category_ids] => ,82,78,76,75,70,
[chemical_name] =>
[weight] => 1014.6
[form] => C46H55Cl3N10O2S4
[cas] => 2948773-23-5
[pslug] => 2948773-23-5-avatrombopag-diamide-impurity-pa012991017
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Avatrombopag Diamide Impurity
Catalogue No.:PA 01 2991017
Molecular Formula : C46H55Cl3N10O2S4
Molecular Weight : 1014.6
stdClass Object
(
[pname] => Avatrombopag 5-Chloro Acid Impurity
[catalogue_number] => PA 01 2991019
[category_ids] => ,82,78,76,75,70,
[chemical_name] =>
[weight] => 649.65
[form] => C29H34Cl2N6O3S2
[cas] => NA
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Avatrombopag 5-Chloro Acid Impurity
Catalogue No.:PA 01 2991019
Molecular Formula : C29H34Cl2N6O3S2
Molecular Weight : 649.65
stdClass Object
(
[pname] => 1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-nitrosopiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid
[catalogue_number] => PA 01 2991018
[category_ids] => ,70,75,76,78,82,
[chemical_name] =>
[weight] => 596.5
[form] => C23H23Cl2N7O4S2
[cas] => NA
[pslug] => 1-3-chloro-5-4-4-chlorothiophen-2-yl-5-4-nitrosopiperazin-1-yl-thiazol-2-yl-carbamoyl-pyridin-2-yl-piperidine-4-carboxylic-acid-pa012991018
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1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-nitrosopiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic Acid
