PK 11195-d3

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Catalogue number:	PA STI 074210
Chemical name:	PK 11195-d3
CAS Number:	NA
Category:	miscellaneous compounds,stable isotopes
Synonyms:	NA
Molecular form:	C₂₁H₁₈D₃ClN₂O
Appearance:	NA
Mol. Weight:	355.88
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	PK 11195-D3 is the isotope labelled analog of PK 11195, a high affinity peripheral benzodiazepine receptor (PBR) ligand. PK 11195 has been shown to regulate protein phosphorylation in rat brain mitochondria under control of Ca2+. PK11195 promotes mitochondrial apoptosis and blocks P-glycoprotein (Pgp)-mediated drug efflux to chemosensitize cancer cells.