Name: Pitavastatin-d5 Lactone
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA STI 074200
Chemical name:	Pitavastatin-d5 Lactone
CAS Number:	NA
Category:	aromatics,chiral standards,enzyme inhibitors,stable isotopes,metabolites,impurities,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	(4R,6S)-6-[(1E)-2-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; [4R-[4α,6β(E)]]-6-[2-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; NK 104-d5; NK 104-d5 (lactone); Nisvastatin-d5; P 872441-d5;
Molecular form:	C₂₅H₁₇D₅FNO₃
Appearance:	Off-White to Pale Yellow Solid
Mol. Weight:	408.48
Storage:	2-8°C Refrigerator,Under Inert Atmosphere
Shipping Conditions:	Ambient
Applications:	A labelled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells.

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Pitavastatin-d5 Lactone

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