PF-3644022-d4

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Catalogue number: PA STI 072200
Chemical name: PF-3644022-d4

CAS Number:

NA
Category: miscellaneous compounds,stable isotopes
Synonyms:

(10R)-9,10,11,12-Tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one-d4;

Molecular form: C21H14D4N4OS
Appearance: NA
Mol. Weight: 378.48
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Labelled analogue of PF-3644022, a potent freely reversible ATP-competitive compound that inhibits MK2 activity (Ki = 3 nM) with good selectivity when profiled against 200 human kinases. PF-3644022 is a benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor α production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation.

PF-3644022-d4

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