vorapaxar and its Impurities

Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction or with peripheral arterial disease. Reference standards of Vorapaxar API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.