Vonoprazan is used in form of the fumarate for the treatment of gastroduodenal ulcer and reflux esophagitis. It is a first-in-class potassium-competitive acid blocker.Reference standards of Vonoprazan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Vonoprazan
Catalogue No.:PA 22 47000
CAS :
Molecular Formula : C17H16FN3O2S
Molecular Weight : 345.39
Vonoprazan Sulfonyl Aldehyde Impurity
Catalogue No.:PA 22 0471001
Molecular Formula : C16H11FN2O3S
Molecular Weight : 330.33
1-(5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471003
Molecular Formula : C17H20FN3O2S
Molecular Weight : 349.42
N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine
Catalogue No.:PA 22 0471004
Molecular Formula : C17H17N3O2S
Molecular Weight : 327.4
N,N-Dimethylmethanamine Vonoprazan
Catalogue No.:PA 22 0471005
Molecular Formula : C18H18FN3O2S
Molecular Weight : 359.42
Vonoprazan Carbaldehyde Impurity
Catalogue No.:PA 22 0471008
Molecular Formula : C11H8FNO
Molecular Weight : 189.19
N-Nitroso Vonoprazan
Catalogue No.:PA 22 0471013
Molecular Formula : C17H15FN4O3S
Molecular Weight : 374.39
Vonoprazan N-Methyl Asparmic Acid Impurity
Catalogue No.:PA 22 0471032
Molecular Formula : C21H20FN3O6S
Molecular Weight : 461.46
2-Fluorobenzaldehyde
Catalogue No.:PA 22 0471041
Molecular Formula : C7H5FO
Molecular Weight : 124.11
1-(5-(3-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine Hydrochloride
Catalogue No.:PA 22 0831001
Molecular Formula : C17H17ClFN3O2S
Molecular Weight : 381.85
1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine Hydrochloride
Catalogue No.:PA 22 0471053
2-Desfluoro Vonoprazan Hydrocloride
Catalogue No.:PA 22 0471055
Molecular Formula : C17H18ClN3O2S
Molecular Weight : 363.86
1-(1-((5-Chloropyridin-3-yl)sulfonyl)-5-(2-fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine Fumarate
Catalogue No.:PA 22 0471059
Molecular Formula : C21H19ClFN3O6S
Molecular Weight : 495.91
Pyridine-4-sulfonyl Chloride
Catalogue No.:PA 22 47510
Molecular Formula : C5H4ClNO2S
Molecular Weight : 177.6
(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanol
Catalogue No.:PA 22 0471000
Molecular Formula : C16H13FN2O3S
Molecular Weight : 332.35
5-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)-1,2,3,4-tetrahydropyridin-2-ol
Catalogue No.:PA 22 0471002
Molecular Formula : C17H20FN3O3S
Molecular Weight : 365.42
(5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methanamine
Catalogue No.:PA 22 0471006
Molecular Formula : C16H18FN3O2S
Molecular Weight : 335.4
N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylaspartic Acid
Catalogue No.:PA 22 0471007
1-(5-(2-Fluorophenyl)-1-(pyridin-4-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471010
1-(5-(3-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471011
1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471009
1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471012
Molecular Formula : C12H13FN2
Molecular Weight : 204.25
2-Chloro Vonoprazan
Catalogue No.:PA 22 0471014
Molecular Formula : C17H15ClFN3O2S
Molecular Weight : 379.83
3-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)pyridine 1-oxide
Catalogue No.:PA 22 0471015
Molecular Formula : C17H16FN3O3S
Molecular Weight : 361.39
N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylhydroxylamine
Catalogue No.:PA 22 0471016
1-(5-(2-Fluorophenyl)-1-(pyridin-2-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471017
1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanimine
Catalogue No.:PA 22 0471018
Molecular Formula : C17H14FN3O2S
Molecular Weight : 343.38
5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylic Acid
Catalogue No.:PA 22 0471019
Molecular Formula : C16H11FN2O4S
Molecular Weight : 346.33
1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanimine Oxide
Catalogue No.:PA 22 0471020
Molecular Formula : C17H14FN3O3S
Molecular Weight : 359.38
2-Chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
Catalogue No.:PA 22 0471021
Molecular Formula : C16H10ClFN2O3S
Molecular Weight : 364.78
5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic Acid
Catalogue No.:PA 22 0471022
Molecular Formula : C11H8FNO2
Molecular Weight : 205.19
2-Chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde
Catalogue No.:PA 22 0471023
Molecular Formula : C11H7ClFNO
Molecular Weight : 223.63
1-(1-((5-Chloropyridin-3-yl)sulfonyl)-5-(2-fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471024
1-(1-((1,6-Dihydropyridin-3-yl)sulfonyl)-5-(2-fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471025
Molecular Formula : C17H18FN3O2S
Molecular Weight : 347.41
1-(5-(2,6-Difluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471026
Molecular Formula : C17H15F2N3O2S
Molecular Weight : 363.38
1,2-bis((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-1,2-dimethylhydrazine
Catalogue No.:PA 22 0471027
Molecular Formula : C34H30F2N6O4S2
Molecular Weight : 688.77
N-((5-(2-Fluorophenyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
Catalogue No.:PA 22 0471028
Molecular Formula : C12H12FN3O
Molecular Weight : 233.25
1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-((5-(2-fluorophenyl)-1H-pyrrol-3-yl)methyl)-N-methylmethanamine
Catalogue No.:PA 22 0471029
Molecular Formula : C23H21F2N3
Molecular Weight : 377.44
(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)methanol
Catalogue No.:PA 22 0471030
Molecular Formula : C11H10FNO
Molecular Weight : 191.21
5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbonitrile
Catalogue No.:PA 22 0471031
Molecular Formula : C16H10FN3O2S
Molecular Weight : 327.33
Pyridine-3-sulfonic Acid
Catalogue No.:PA 22 0471033
Molecular Formula : C5H5NO3S
Molecular Weight : 159.16
N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)ethanamine Fumarate
Catalogue No.:PA 22 0471034
Molecular Formula : C22H22FN3O6S
Molecular Weight : 475.49
N-((5-(2-Fluorophenyl)-1-((6-hydroxy-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
Catalogue No.:PA 22 0471035
Molecular Formula : C17H19FN4O4S
Molecular Weight : 394.42
5-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)-1-nitroso-1,2,3,4-tetrahydropyridin-2-ol
Catalogue No.:PA 22 0471036
N-((5-(2-Fluorophenyl)-1-((6-hydroxy-1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
Catalogue No.:PA 22 0471037
Molecular Formula : C17H18FN5O5S
Molecular Weight : 423.42
N-((5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
Catalogue No.:PA 22 0471038
Molecular Formula : C17H19FN4O3S
Molecular Weight : 378.42
1-(5-(2-Fluorophenyl)-1-((1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Catalogue No.:PA 22 0471039
N-((5-(2-Fluorophenyl)-1-((1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
Catalogue No.:PA 22 0471040
Molecular Formula : C17H18FN5O4S
Molecular Weight : 407.42
2-(2-(2-Fluorophenyl)-2-oxoethyl)malononitrile
Catalogue No.:PA 22 0471042
Molecular Formula : C11H7FN2O
Molecular Weight : 202.19
2-Chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
Catalogue No.:PA 22 0471043
Molecular Formula : C11H6ClFN2
Molecular Weight : 220.63
5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile
Catalogue No.:PA 22 0471044
Molecular Formula : C11H7FN2
Molecular Weight : 186.19
N-Nitroso Vonoprazan-D3
Catalogue No.:PA STI 089616
Molecular Formula : C17H12D3FN4O3S
Molecular Weight : 377.41
1,2-Di(pyridin-3-yl)disulfane
Catalogue No.:PA 22 0471045
Molecular Formula : C10H8N2S2
Molecular Weight : 220.31
N-Nitroso Vonoprazan-13CD3
Catalogue No.:PA STI 089624
Molecular Formula : C1613CH12D3FN4O3S
Molecular Weight : 378.4
(5-(4-Fluorophenyl)-1H-pyrrol-3-yl)methanol
Catalogue No.:PA 22 0471046
(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine
Catalogue No.:PA 22 0471047
Molecular Formula : C16H14FN3O2S
Molecular Weight : 331.37
((5-(2-Fluoro-4-hydroxyphenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)(methyl)sulfamic Acid
Catalogue No.:PA 22 0471048
Molecular Formula : C17H16FN3O6S2
Molecular Weight : 441.45
1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine Fumarate
Catalogue No.:PA 22 0471049
Molecular Formula : C16H17FN2O4
Molecular Weight : 320.32
N,N-Dimethylmethanamine Vonoprazan Fumarate Salt
Catalogue No.:PA 22 0471050
5-Chloropyridine-3-sulfonic Acid
Catalogue No.:PA 22 0471051
Molecular Formula : C5H4ClNO3S
Molecular Weight : 193.6
3,5-Pyridinedisulfonyl dichloride
Catalogue No.:PA 22 0471052
Molecular Formula : C5H3Cl2NO4S2
Molecular Weight : 276.1
5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
Catalogue No.:PAI 22 047001
Molecular Formula : C16H12N2O3S
Molecular Weight : 312.34
5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
Catalogue No.:PAI 22 047002
5-Bromo-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
Catalogue No.:PAI 22 047003
Molecular Formula : C10H7BrN2O3S
Molecular Weight : 315.14
5-(3-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde
Catalogue No.:PAI 22 047004
N-Nitroso Vonoprazan-D4
Catalogue No.:PA STI 089728
Molecular Formula : C17H11D4FN4O3S
Molecular Weight : 378.41
1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine Hydrochloride
Catalogue No.:PA 22 0471054
Molecular Formula : C12H14ClFN2
Molecular Weight : 240.71
Ethyl 2-cyano-4-(2-fluorophenyl)-4-oxobutanoate
Catalogue No.:PA 22 0471056
Molecular Formula : C13H12FNO3
Molecular Weight : 249.24
Ethyl 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate
Catalogue No.:PA 22 0471057
Molecular Formula : C13H11ClFNO2
Molecular Weight : 267.68
Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate
Catalogue No.:PA 22 0471058
Molecular Formula : C13H12FNO2
Molecular Weight : 233.24
5-(2-Fluorophenyl)-N-methyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxamide
Catalogue No.:PA 22 0471060
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