Varenicline is used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. It is a prescription medication. Varenicline trade name is Chantix and Champix.Reference standards of Varenicline API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Varenicline
Catalogue No.:PA 22 18000
CAS :
Molecular Formula : C13H13N3
Molecular Weight : 211.26
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
Catalogue No.:PA 22 18510
Molecular Formula : C13H14F3N3O
Molecular Weight : 285.26
8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline
Catalogue No.:PA 22 18520
Molecular Formula : C15H12F3N3O
Molecular Weight : 307.27
1,5,6,7,8,9-Hexahydro-5,9-methanoimidazol[4,5,h][3]benzazepine Dihydrochloride
Catalogue No.:PA 22 18530
Molecular Formula : C12H15Cl2N3
Molecular Weight : 272.17
2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine-7,8-diamine
Catalogue No.:PA 22 18540
Molecular Formula : C11H15N3
Molecular Weight : 189.26
2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepine-6,8-diamine
Catalogue No.:PA 22 18550
Methyl Varenicline
Catalogue No.:PA 22 18560
Molecular Formula : C14H15N3
Molecular Weight : 225.29
Varenicline Carbamoyl β-D-Glucuronide-d4
Catalogue No.:PA STI 086730
Molecular Formula : C20H16D4N3O8
Molecular Weight : 435.42
Varenicline-d4 Dihydrochloride
Catalogue No.:PA STI 086740
Molecular Formula : C13H11D4Cl2N3
Molecular Weight : 288.21
Varenicline-d2,15N2 Dihydrochloride
Catalogue No.:PA STI 086750
Molecular Formula : C13H13D2Cl2N15N2
Molecular Weight : 288.18
Varenicline-13C2,15N2
Catalogue No.:PA STI 086751
Molecular Formula : C1113C2H13N15N2
Molecular Weight : 215.23
N-Formyl Varenicline
Catalogue No.:PA 22 18570
Molecular Formula : C14H13N3O
Molecular Weight : 239.28
9-Nitro-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepin-7-amine
Catalogue No.:PA 22 18580
Molecular Formula : C11H13N3O2
Molecular Weight : 219.24
7,8,9,10-Tetrahydro-8-methyl-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine
Catalogue No.:PA 22 18590
Molecular Weight : 225.3
1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo[4',5':4,5]benzo[1,2-d]azepine
Catalogue No.:PA 22 18600
Molecular Formula : C12H13N3
Molecular Weight : 199.26
7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-2-ol
Catalogue No.:PA 22 18610
Molecular Formula : C13H13N3O
Molecular Weight : 227.27
1-((1S,5R)-7-Amino-8-nitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 18620
Molecular Formula : C13H12F3N3O3
Molecular Weight : 315.25
8-Oxo-7,8,9,10-tetrahydro-6H-8λ4-6,10-methanoazepino[4,5-g]quinoxaline
Catalogue No.:PA 22 18630
(1S,5R)-8-Nitro-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepin-7-amine
Catalogue No.:PA 22 18640
2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepin-7-amine Oxalate
Catalogue No.:PA 22 18650
Molecular Formula : C13H16N2O4
Molecular Weight : 264.28
Varenicline Dioxo Impurity
Catalogue No.:PA 22 18660
Molecular Formula : C13H13N3O2
Molecular Weight : 243.27
2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
Catalogue No.:PA 22 18670
Molecular Formula : C13H10F3N3O5
Molecular Weight : 345.23
1-(6,8-Dinitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 18680
2,2,2-Trifluoro-1-(7-nitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)ethan-1-one
Catalogue No.:PA 22 18690
Molecular Formula : C13H11F3N2O3
Molecular Weight : 300.24
1-(6,8-Diamino-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 18700
Molecular Weight : 285.27
N-Acetyl Varenicline
Catalogue No.:PA 22 18730
Molecular Formula : C15H15N3O
Molecular Weight : 253.31
Varenicline Carbamoyl β-D-Glucuronide
Catalogue No.:PA 22 18740
Molecular Formula : C20H21N3O8
Molecular Weight : 431.4
Varenicline N-Glucoside
Catalogue No.:PA 22 18750
Molecular Formula : C19H23N3O5
Molecular Weight : 373.4
(6R,10S)-6,7,9,10-Tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxaline-8-carboxylic Acid
Catalogue No.:PA 22 18760
Molecular Formula : C14H13N3O2
Molecular Weight : 255.28
2-Methyl-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline 2,3-dihydroxysuccinate
Catalogue No.:PA 22 18770
Molecular Formula : C18H21N3O6
Molecular Weight : 375.38
(6R,10S)-7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline 1-Oxide
Catalogue No.:PA 22 0181000
Hydroxy Varenicline
Catalogue No.:PA 22 0181002
2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepin-7-amine
Catalogue No.:PA 22 0181003
Molecular Formula : C11H14N2
Molecular Weight : 174.25
Depyrazine 7,8-Dinitrophenyl Varenicline
Catalogue No.:PA 22 0181004
Molecular Formula : C11H11N3O4
Molecular Weight : 249.23
Depyrazine 6,8-Dinitrophenyl Varenicline
Catalogue No.:PA 22 0181005
7-Nitro-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine
Catalogue No.:PA 22 0181006
Molecular Formula : C11H12N2O2
Molecular Weight : 204.23
1-(7-Amino-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 0181007
Molecular Formula : C13H13F3N2O
Molecular Weight : 270.26
bis(6,7,9,10-Tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)methanone
Catalogue No.:PA 22 0181008
Molecular Formula : C27H24N6O
Molecular Weight : 448.53
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
Catalogue No.:PA 22 0181009
Molecular Formula : C13H12F3NO
Molecular Weight : 255.24
Depyrazine 7-Nitro-8-aminophenyl N-Trifluoroacetyl Varenicline
Catalogue No.:PA 22 0181010
2,2,2-Trifluoro-1-(5,6,8,9-tetrahydro-5,9-ethanoimidazo[4',5':4,5]benzo[1,2-d]azepin-7(1H)-yl)ethan-1-one
Catalogue No.:PA 22 0181011
Molecular Formula : C15H14F3N3O
Molecular Weight : 309.29
2,2,2-Trifluoro-1-(5,6,8,9-tetrahydro-5,9-methanoimidazo[4',5':4,5]benzo[1,2-d]azepin-7(1H)-yl)ethan-1-one
Catalogue No.:PA 22 0181012
Molecular Formula : C14H12F3N3O
Molecular Weight : 295.27
7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline 1,4-dioxide
Catalogue No.:PA 22 0181001
8-Nitroso-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline
Catalogue No.:PA 22 0181013
Molecular Formula : C13H12N4O
Molecular Weight : 240.27
7,8-Dinitro-3-nitroso-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine
Catalogue No.:PA 22 0181014
Molecular Formula : C11H10N4O5
Molecular Weight : 278.22
(1R,5S)-2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepine-7,8-diamine
Catalogue No.:PA 22 0181015
(6R,10S)-3-Hydroxy-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline 1-Oxide
Catalogue No.:PA 22 0181016
2-Hydroxy-2-((6R,10S)-6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)acetaldehyde
Catalogue No.:PA 22 0181017
Molecular Formula : C15H15N3O2
Molecular Weight : 269.3
1-((1S,5R)-7-Amino-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 0181018
1-((6S,10R)-6,7,9,10-Tetrahydro-8H-6,10-methanoazepino[4,5-g]quinolin-8-yl)ethane-1,2-diol
Catalogue No.:PA 22 0181019
Molecular Formula : C16H18N2O2
Molecular Weight : 270.33
4,6,7,8,9,10-Hexahydro-1H-6,10-methanoazepino[4,5-g]quinoxaline-2,3-dione Hydrochloride
Catalogue No.:PA 22 0181020
Molecular Formula : C13H14ClN3O2
Molecular Weight : 279.72
Hydroxy Varenicline N-Trifluoroacetic Amide
Catalogue No.:PA 22 0181021
Molecular Formula : C15H12F3N3O2
Molecular Weight : 323.28
1-(1,3-Dinitro-6,7,8,9-tetrahydro-5H-5,9-methanobenzo[7]annulen-7-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 0181022
Molecular Formula : C14H11F3N2O5
Molecular Weight : 344.25
1,2-bis((6R,10S)-6,7,9,10-Tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)ethan-1-one
Catalogue No.:PA 22 0181023
Molecular Formula : C28H26N6O
Molecular Weight : 462.56
(7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-2-yl)methanol
Catalogue No.:PA 22 0181024
Molecular Formula : C14H15N3O
Molecular Weight : 241.29
3-Nitroso-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine-7,8-diamine
Catalogue No.:PA 22 0181025
Molecular Formula : C11H14N4O
Molecular Weight : 218.26
2,3-Dihydroxy-4-oxo-4-(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)butanoic acid
Catalogue No.:PA 22 0181026
Molecular Formula : C17H17N3O5
Molecular Weight : 343.34
Ethane-1,1,2-triol
Catalogue No.:PA 22 0181027
Molecular Formula : C2H6O3
Molecular Weight : 78.07
Dihydroxyacetaldehyde
Catalogue No.:PA 22 0181028
Molecular Formula : C2H4O3
Molecular Weight : 76.05
3-Hydroxy-2-oxopropanal
Catalogue No.:PA 22 0181029
Molecular Formula : C3H4O3
Molecular Weight : 88.06
Varenicline-d4
Catalogue No.:PA STI 088970
Molecular Formula : C13H9D4N3
Molecular Weight : 215.29
7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline-13C2 15N2
Catalogue No.:PA 22 0181030
Molecular Weight : 215.24
Varenicline N-oxide
Catalogue No.:PA 22 0181031
1,2,4,5-Tetrahydro-3H-1,5-methanobenzo[d]azepine-3,7,8-triamine
Catalogue No.:PA 22 0181032
Molecular Formula : C11H16N4
Molecular Weight : 204.28
3-Nitroso-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine
Catalogue No.:PA 22 0181033
Molecular Formula : C11H12N2O
Molecular Weight : 188.23
((6R,10S)-7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-2-yl)methanol
Catalogue No.:PA 22 0181034
(1R,5S)-3-Nitroso-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine-7,8-diamine
Catalogue No.:PA 22 0181035
(1R,5S)-7,8-Dinitro-3-nitroso-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine
Catalogue No.:PA 22 0181036
(1R,5S)-3-Nitroso-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine
Catalogue No.:PA 22 0181037
2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepine
Catalogue No.:PA 22 0181038
Molecular Formula : C11H13N
Molecular Weight : 159.23
7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-5-ol
Catalogue No.:PA 22 0181039
1-(7,8-Dinitroso-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 0181043
Molecular Formula : C13H10F3N3O3
Molecular Weight : 313.24
1-(7,8-bis(Hydroxyamino)-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 0181042
Molecular Formula : C13H14F3N3O3
Molecular Weight : 317.27
2,2,2-Trifluoro-1-(7-(hydroxyamino)-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)ethan-1-one
Catalogue No.:PA 22 0181041
Molecular Formula : C13H13F3N2O2
Molecular Weight : 286.25
2,2,2-Trifluoro-1-(7-nitroso-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)ethan-1-one
Catalogue No.:PA 22 0181040
Molecular Formula : C13H11F3N2O2
Molecular Weight : 284.24
2,3,4,5-Tetrahydro-1H-1,5-methanobenzo[d]azepine Hydrochloride
Catalogue No.:PA 22 0181044
Molecular Formula : C11H14ClN
Molecular Weight : 195.69
(3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6R)-4,5-Dihydroxy-2-(hydroxymethyl)-6-(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 22 0181045
Molecular Formula : C25H33N3O10
Molecular Weight : 535.55
2-((2-((4,5-Dihydroxy-2-(hydroxymethyl)-6-(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 22 0181046
Molecular Formula : C31H43N3O15
Molecular Weight : 697.69
7-Nitro-3-nitroso-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine
Catalogue No.:PA 22 0181047
Molecular Formula : C11H11N3O3
Molecular Weight : 233.23
1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo[4',5':4,5]benzo[1,2-d]azepine Hydrochloride
Catalogue No.:PA 22 0181048
Molecular Formula : C12H14ClN3
Molecular Weight : 235.72
3-Benzyl-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine
Catalogue No.:PA 22 0181049
Molecular Formula : C18H19N
Molecular Weight : 249.36
2-Hydroxy-4-Oxo-Varenicline
Catalogue No.:PA 22 0181050
Varenicline Nitroso D4
Catalogue No.:PA STI 089600
Molecular Formula : C13H8D4N4O
Molecular Weight : 244.29
1-((1R,5S)-8-Amino-6-nitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Catalogue No.:PA 22 0181051
(2R,3R)-2,3-Dihydroxy-1,4-bis(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)butane-1,4-dione
Catalogue No.:PA 22 0181052
Molecular Formula : C30H28N6O4
Molecular Weight : 536.59
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