Upadacitinib-impurities | Pharmaffiliates

Upadacitinib and its Impurities

Upadacitinib, sold under the brand name Rinvoq, is a Janus kinase (JAK) inhibitor medication for the treatment of moderately to severely active rheumatoid arthritis in adults. where, its methotrexate a drug used to treat active arthritis. Reference standards of Upadacitinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 26 results for Upadacitinib Impurities
PA 21 0180000

Upadacitinib - API Standards

Upadacitinib

  • Catalogue No.:PA 21 0180000

  • CAS :

    1310726-60-3

  • Molecular Formula : C17H19F3N6O

  • Molecular Weight : 380.38

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PA 21 0181000

(3S,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

(3S,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181000

  • CAS :

    NA

  • Molecular Formula : C17H19F3N6O

  • Molecular Weight : 380.38

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PA 21 0181002

(3R,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

(3R,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181002

  • CAS :

    NA

  • Molecular Formula : C17H19F3N6O

  • Molecular Weight : 380.38

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PA 21 0181003

(3S,4R)-3-Ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

(3S,4R)-3-Ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181003

  • CAS :

    2411540-30-0

  • Molecular Formula : C24H25F3N6O3S

  • Molecular Weight : 534.56

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PA 21 0181004

Benzyl (3S,4S)-3-acetyl-4-ethylpyrrolidine-1-carboxylate

Benzyl (3S,4S)-3-acetyl-4-ethylpyrrolidine-1-carboxylate

  • Catalogue No.:PA 21 0181004

  • CAS :

    2868258-95-9

  • Molecular Formula : C16H21NO3

  • Molecular Weight : 275.35

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PA 21 0181005

Benzyl (3R,4S)-3-(2,2-dibromoacetyl)-4-ethylpyrrolidine-1-carboxylate

Benzyl (3R,4S)-3-(2,2-dibromoacetyl)-4-ethylpyrrolidine-1-carboxylate

  • Catalogue No.:PA 21 0181005

  • CAS :

    NA

  • Molecular Formula : C16H19Br2NO3

  • Molecular Weight : 433.14

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PA 21 0181006

8-((3R,4S)-4-Ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine

8-((3R,4S)-4-Ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine

  • Catalogue No.:PA 21 0181006

  • CAS :

    1708997-43-6

  • Molecular Formula : C14H17N5

  • Molecular Weight : 255.33

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PA 21 0181007

(3R,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

(3R,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181007

  • CAS :

    1310726-59-0

  • Molecular Formula : C17H19F3N6O

  • Molecular Weight : 380.38

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PA 21 0181008

rel-(3R,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

rel-(3R,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181008

  • CAS :

    1831899-72-9

  • Molecular Formula : C17H19F3N6O

  • Molecular Weight : 380.38

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PA 21 0181009

(3S,4R)-3-Ethyl-4-(3-nitroso-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

(3S,4R)-3-Ethyl-4-(3-nitroso-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181009

  • CAS :

    NA

  • Molecular Formula : C17H18F3N7O2

  • Molecular Weight : 409.37

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PA 21 0181010

(S)-N-Ethyl-3-(3-nitroso-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

(S)-N-Ethyl-3-(3-nitroso-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181010

  • CAS :

    NA

  • Molecular Formula : C17H18F3N7O2

  • Molecular Weight : 409.37

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PA STI 089629

Upadacitinib-15N-d2

Upadacitinib-15N-d2

  • Catalogue No.:PA STI 089629

  • CAS :

    NA

  • Molecular Formula : C17H17D2F3N515NO

  • Molecular Weight : 383.38

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PA 21 0181011

Benzyl (3R,4S)-3-(2-chloroacetyl)-4-ethylpyrrolidine-1-carboxylate

Benzyl (3R,4S)-3-(2-chloroacetyl)-4-ethylpyrrolidine-1-carboxylate

  • Catalogue No.:PA 21 0181011

  • CAS :

    2460133-49-5

  • Molecular Formula : C16H20ClNO3

  • Molecular Weight : 309.79

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PA 21 0181012

(3S,4R)-3-Ethyl-4-(3-(hydroxymethyl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

(3S,4R)-3-Ethyl-4-(3-(hydroxymethyl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181012

  • CAS :

    NA

  • Molecular Formula : C18H21F3N6O2

  • Molecular Weight : 410.4

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PA 21 0181013

Benzyl (3S,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate

Benzyl (3S,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate

  • Catalogue No.:PA 21 0181013

  • CAS :

    2868258-96-0

  • Molecular Formula : C16H20BrNO3

  • Molecular Weight : 354.24

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PA 21 0181021

N-Methyl Upadacitinib

N-Methyl Upadacitinib

  • Catalogue No.:PA 21 0181021

  • CAS :

    NA

  • Molecular Formula : C18H21F3N6O

  • Molecular Weight : 394.4

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PA 21 0181014

8-((3R,4S)-4-Ethylpyrrolidin-3-yl)-3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine

8-((3R,4S)-4-Ethylpyrrolidin-3-yl)-3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine

  • Catalogue No.:PA 21 0181014

  • CAS :

    1428243-28-0

  • Molecular Formula : C21H23N5O2S

  • Molecular Weight : 409.51

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PA 21 0181015

8-((3R,4S)-4-Ethyl-1-tosylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine

8-((3R,4S)-4-Ethyl-1-tosylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine

  • Catalogue No.:PA 21 0181015

  • CAS :

    2952578-02-6

  • Molecular Formula : C21H23N5O2S

  • Molecular Weight : 409.51

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PA 21 0181016

1-((3S,4R)-3-Ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidin-1-yl)-2,2,2-trifluoroethan-1-one

1-((3S,4R)-3-Ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidin-1-yl)-2,2,2-trifluoroethan-1-one

  • Catalogue No.:PA 21 0181016

  • CAS :

    2768445-19-6

  • Molecular Formula : C23H22F3N5O3S

  • Molecular Weight : 505.52

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PA 21 0181017

8-((3R,4S)-4-Ethyl-1-tosylpyrrolidin-3-yl)-3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine

8-((3R,4S)-4-Ethyl-1-tosylpyrrolidin-3-yl)-3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine

  • Catalogue No.:PA 21 0181017

  • CAS :

    NA

  • Molecular Formula : C28H29N5O4S2

  • Molecular Weight : 563.69

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PA 21 0181018

Benzyl (3S,4R)-3-ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidine-1-carboxylate

Benzyl (3S,4R)-3-ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidine-1-carboxylate

  • Catalogue No.:PA 21 0181018

  • CAS :

    1708997-42-5

  • Molecular Formula : C29H29N5O4S

  • Molecular Weight : 543.64

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PA 21 0181019

(3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidine-1-carboxamide

(3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181019

  • CAS :

    NA

  • Molecular Formula : C15H18N6O

  • Molecular Weight : 298.35

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PA 21 0181020

8-((3R,4S)-4-Ethyl-1-((2,2,2-trifluoroethyl)carbamoyl)pyrrolidin-3-yl)-N-(2,2,2-trifluoroethyl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine-3-carboxamide

8-((3R,4S)-4-Ethyl-1-((2,2,2-trifluoroethyl)carbamoyl)pyrrolidin-3-yl)-N-(2,2,2-trifluoroethyl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine-3-carboxamide

  • Catalogue No.:PA 21 0181020

  • CAS :

    2715120-86-6

  • Molecular Formula : C20H21F6N7O2

  • Molecular Weight : 505.43

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PA STI 089740

Upadacitinib D4

Upadacitinib D4

  • Catalogue No.:PA STI 089740

  • CAS :

    NA

  • Molecular Formula : C17H15D4F3N6O

  • Molecular Weight : 384.4

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PA 21 0181022

Benzyl (3R,4S)-3-acetyl-4-ethylpyrrolidine-1-carboxylate

Benzyl (3R,4S)-3-acetyl-4-ethylpyrrolidine-1-carboxylate

  • Catalogue No.:PA 21 0181022

  • CAS :

    2411540-29-7

  • Molecular Formula : C16H21NO3

  • Molecular Weight : 275.35

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PA 21 0181023

(3R,4S)-3-Ethyl-4-(3-(hydroxymethyl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

(3R,4S)-3-Ethyl-4-(3-(hydroxymethyl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

  • Catalogue No.:PA 21 0181023

  • CAS :

    NA

  • Molecular Formula : C18H21F3N6O2

  • Molecular Weight : 410.4

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