Ubrogepant and its Impurities
Ubrogepant, sold under the brand name Ubrelvy, is a medication used for the acute treatment of migraine. Reference standards of Ubrogepant API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

![(R)-2'-Oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b] PA 21 0251000](https://www.pharmaffiliates.com/pimages/PA210251000.jpg)
(R)-2'-Oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylic Acid
(R)-2'-Oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylic Acid
Catalogue No.:PA 21 0251000
CAS :
2568065-21-2
Molecular Formula : C15H11N3O3
Molecular Weight : 281.27

![(S)-1'-(tert-Butyl)-5,7-dihydrospiro[cyclopenta[b] PA 21 0251001](https://www.pharmaffiliates.com/pimages/PA210251001.jpg)
(S)-1'-(tert-Butyl)-5,7-dihydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one
(S)-1'-(tert-Butyl)-5,7-dihydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one
Catalogue No.:PA 21 0251001
CAS :
2408280-91-9
Molecular Formula : C18H19N3O
Molecular Weight : 293.37


(R)-1'-(tert-Butyl)-3-chloro-5,7-dihydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one
(R)-1'-(tert-Butyl)-3-chloro-5,7-dihydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one
Catalogue No.:PA 21 0251002
CAS :
1456803-73-8
Molecular Formula : C18H18ClN3O
Molecular Weight : 327.81


tert-Butyl ((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)carbamate
tert-Butyl ((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)carbamate
Catalogue No.:PA 21 0251004
CAS :
1456803-35-2
Molecular Formula : C19H25F3N2O3
Molecular Weight : 386.42


tert-Butyl ((3R,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)carbamate
tert-Butyl ((3R,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)carbamate
Catalogue No.:PA 21 0251005
CAS :
1456803-36-3
Molecular Formula : C19H25F3N2O3
Molecular Weight : 386.42


tert-Butyl ((5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)(2,2,2-trifluoroethyl)carbamate
tert-Butyl ((5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)(2,2,2-trifluoroethyl)carbamate
Catalogue No.:PA 21 0251006
CAS :
1456803-34-1
Molecular Formula : C21H26F6N2O3
Molecular Weight : 468.44