Tucatinib, sold under the brand name Tukysa, is a small molecule inhibitor of HER2 for the treatment of HER2-positive breast cancer. Reference standards of Tucatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Tucatinib
Catalogue No.:PA 20 3360000
CAS :
Molecular Formula : C26H24N8O2
Molecular Weight : 480.53
4,6-Quinazolinediamine, N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]
Catalogue No.:PA 20 3361000
Molecular Formula : C21H17N7O
Molecular Weight : 383.42
1-(4-((4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)-3-(1-hydroxy-2-methylpropan-2-yl)thiourea
Catalogue No.:PA 20 3361001
Molecular Formula : C26H26N8O2S
Molecular Weight : 514.61
1-(4-((4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)-4,4-dimethylimidazolidine-2-thione
Catalogue No.:PA 20 3361002
Molecular Formula : C26H24N8OS
Molecular Weight : 496.59
N4-(4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrothiazol-2-yl)quinazoline-4,6-diamine
Catalogue No.:PA 20 3361003
4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline
Catalogue No.:PA 20 3361004
Molecular Formula : C13H12N4O
Molecular Weight : 240.27
Tucatinib Hemiethanolate
Catalogue No.:PA 20 3361005
Molecular Formula : C54H54N16O5
Molecular Weight : 1007.13
2-Amino-2-methylpropyl (4-((4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)carbamate
Catalogue No.:PA 20 3361006
Molecular Formula : C26H26N8O3
Molecular Weight : 498.55
7-(2-Methyl-4-nitrophenoxy)-[1,2,4]triazolo[1,5-a]pyridine
Catalogue No.:PA 20 3361007
Molecular Formula : C13H10N4O3
Molecular Weight : 270.25
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