Tolvaptan Phosphate Disodium and its Impurities

Tolvaptan Phosphate Disodium, sold under the brand name Samsca among others, is an aquaretic drug. it is a drug used for the treatment of cardiac edema. Reference standards of Tolvaptan Phosphate Disodium API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.