A janus kinase (JAK) inhibitor class of drug used for the treatment of rheumatoid arthritis (RA)Reference standards of Tofacitinib Citrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Tofacitinib Citrate
Catalogue No.:PA 47 13000
CAS :
Molecular Formula : C22H28N6O8
Molecular Weight : 504.49
(3R,4S)-Tofacitinib
Catalogue No.:PA 47 13510
Molecular Formula : C16H20N6O
Molecular Weight : 312.37
(3S,4R)-Tofacitinib
Catalogue No.:PA 47 13520
N-((3S,4S)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13650
Molecular Formula : C20H25N5
Molecular Weight : 335.45
Tofacitinib N-Oxide
Catalogue No.:PA 47 13700
Molecular Formula : C16H20N6O2
Molecular Weight : 328.38
N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13730
Molecular Formula : C13H19N5
Molecular Weight : 245.33
3-(4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate
Catalogue No.:PA 47 13750
Molecular Weight : 504.5
3-((3R,4R)-4-Methyl-3-(methyl(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13820
(3S,4S)-Tofacitinib
Catalogue No.:PA 47 13530
N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Catalogue No.:PA 47 13540
Molecular Weight : 245.32
3-((3R,4R)-4-Methyl-3-(methylamino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13550
Molecular Formula : C11H18N2O
Molecular Weight : 194.27
2-Cyano-N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methylacetamide
Catalogue No.:PA 47 13560
Molecular Formula : C13H18N4O2
Molecular Weight : 262.31
N,4-Dimethyl-1-benzyl-3-piperidinamine
Catalogue No.:PA 47 13570
Molecular Formula : C14H22N2
Molecular Weight : 218.34
(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
Catalogue No.:PA 47 13580
Molecular Formula : C14H24Cl2N2
Molecular Weight : 291.26
(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
Catalogue No.:PA 47 13590
3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid
Catalogue No.:PA 47 13600
Molecular Formula : C16H21N5O3
Molecular Weight : 331.37
3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide
Catalogue No.:PA 47 13610
Molecular Formula : C16H22N6O2
Molecular Weight : 330.38
N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13630
Des-(N-oxopropanenitrile)-N-methylbenzyl
Catalogue No.:PA 47 13640
3-(4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13660
6-Chloro-7-deazapurine
Catalogue No.:PA 47 13670
Molecular Formula : C6H4ClN3
Molecular Weight : 153.57
4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 13680
Molecular Formula : C13H10ClN3O2S
Molecular Weight : 307.76
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13690
Molecular Formula : C21H27N5
Molecular Weight : 349.47
1-((3R,4R)-4-Methyl-3-(methyl(1H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one
Catalogue No.:PA 47 13710
Molecular Formula : C15H21N5O
Molecular Weight : 287.37
N-((3R,4R)-1,4-Dimethylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13720
Molecular Formula : C14H21N5
Molecular Weight : 259.36
3-((3R,4R)-3-((6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate
Catalogue No.:PA 47 13740
Molecular Formula : C22H30N6O8
Molecular Weight : 506.52
3-((3S,4S)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-Hydroxypropane-1,2,3-tricarboxylate
Catalogue No.:PA 47 13760
SR-Tofacitinib Citirate
Catalogue No.:PA 47 13770
3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13780
Molecular Formula : C16H22N6O3
Molecular Weight : 346.39
3-((3R,4R)-3-(((5R,6S)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13790
3-((3R,4R)-4-Methyl-3-(methyl((5R,6S)-2,5,6-trihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13800
Molecular Formula : C16H22N6O4
Molecular Weight : 362.39
3-((3R,4R)-4-Methyl-3-(methyl((5S,6R)-2,5,6-trihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13810
Ethyl 4-cyano-3-imino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentanoate
Catalogue No.:PA 47 13830
Molecular Formula : C21H27N7O3
Molecular Weight : 425.49
3-Imino-5-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)-5-oxopentanenitrile
Catalogue No.:PA 47 13840
Molecular Formula : C33H41N11O2
Molecular Weight : 623.77
3-((3R,4R)-3-((2-Chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13850
Molecular Formula : C16H19ClN6O
Molecular Weight : 346.82
(3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide
Catalogue No.:PA 47 13860
Molecular Formula : C13H19N5O
Molecular Weight : 261.33
2-Chloro-1H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 13870
2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 13880
Molecular Formula : C6H3Cl2N3
Molecular Weight : 188.01
(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
Catalogue No.:PA 47 13890
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 0131000
Molecular Formula : C27H31N5O2S
Molecular Weight : 489.64
N-((3R,4R)-1-Ethyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 0131001
Molecular Formula : C15H23N5
Molecular Weight : 273.38
Butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate
Catalogue No.:PA 47 0131002
Molecular Formula : C20H29N5O3
Molecular Weight : 387.48
3-(4-(((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 0131003
Molecular Formula : C19H21N7O2
Molecular Weight : 379.42
4'-Chloro-4,7'-bi-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 0131004
Molecular Formula : C12H7ClN6
Molecular Weight : 270.68
1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one
Catalogue No.:PA 47 0131005
Ethyl 4-cyano-5-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-imino-5-oxopentanoate
Catalogue No.:PAI 47 013001
Molecular Formula : C21H29N7O3
Molecular Weight : 427.51
Tofacitinib Citrate (IPRST025)
Catalogue No.:PA IPRST025
Molecular Formula : NA
Molecular Weight : NA
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methylnitrous amide
Catalogue No.:PA 47 0131006
Molecular Formula : C14H21N3O
Molecular Weight : 247.34
4-Cyano-2-hydroxy-5-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentane-1,2,3-tricarboxylic Acid
Catalogue No.:PA 47 0131007
Molecular Formula : C22H26N6O8
Molecular Weight : 502.48
(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine
Catalogue No.:PA 47 0131008
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