Tadalafil is used to treat male erectile dysfunction. It is marketed worldwide under the brand name Cialis. Tadalafil is an orally administered drug.Reference standards of Tadalafil API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Tadalafil
Catalogue No.:PA 20 02000
CAS :
Molecular Formula : C22H19N3O4
Molecular Weight : 389.40
(6R,12aS)-6-(1,3-Benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
Catalogue No.:PA 20 02010
(6S,12aS)-6-(1,3-Benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
Catalogue No.:PA 20 02020
(6S,12aR)-6-(1,3-Benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
Catalogue No.:PA 20 02030
Spiro-oxindole
Catalogue No.:PA 20 02090
Molecular Formula : C22H19N3O5
Molecular Weight : 405.40
N-Butyl Nortadalafil
Catalogue No.:PA 20 02540
Molecular Formula : C25H25N3O4
Molecular Weight : 431.48
(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 02550
Molecular Formula : C22H19ClN2O5
Molecular Weight : 426.85
Tadalafil N-Desmethyl N-Amino
Catalogue No.:PA 20 02730
Molecular Formula : C21H18N4O4
Molecular Weight : 390.4
(3R)-3-[[2-(1,3-Benzodioxol-5-ylcarbonyl)-1H-indol-3-yl]methyl]-1-methyl-2,5-piperazinedione
Catalogue No.:PA 20 0021000
Molecular Weight : 405.41
N-(1-(Benzo[d][1,3]dioxol-5-yl)-9H-pyrido[3,4-b]indole-3-carbonyl)-N-methylglycine
Catalogue No.:PA 20 0021001
Molecular Formula : C22H17N3O5
Molecular Weight : 403.39
Methyl (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-2-(dimethylglycyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 0021009
Molecular Formula : C24H25N3O5
Molecular Weight : 435.48
(6bR)-12-(1,3-Benzodioxol-5-yl)-12a-hydroxy-8-methyl-6a,6b,8,9,12,12a-hexahydropyrazino[1′,2′:1,2]pyrrolo[3,4-c]quinoline-6,7,10(5H)-trione
Catalogue No.:PA 20 02040
Molecular Formula : C22H19N3O6
Molecular Weight : 421.40
Aminohemiketal
Catalogue No.:PA 20 02050
(8a′R)-6′-(1,3-Benzodioxol-5-yl)-2′-methyl-2′,3′,8′,8a′-tetrahydro-6′H-spiro[3,1-benzoxazine-4,7′-pyrrolo[1,2-a]pyrazine]-1′,2,4′(1H)-trione
Catalogue No.:PA 20 02060
(12bR)-6-(1,3-Benzodioxol-5-yl)-12-hydroxy-2-methyl-2,3,6,12b-tetrahydropyrazino[1′,2′:1,5]pyrrolo[3,4-b]quinoline-1,4-dione
Catalogue No.:PA 20 02070
Tadalafil Ketolactam
Catalogue No.:PA 20 02080
2'-Oxo Tadalafil
Catalogue No.:PA 20 02520
Tadalafil Epoxide
Catalogue No.:PA 20 02530
Molecular Weight : 405.4
(1R,3S)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 02560
Molecular Formula : C20H18N2O4
Molecular Weight : 350.37
(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester
Catalogue No.:PA 20 02570
(1S,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 02580
(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester
Catalogue No.:PA 20 02590
(1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester
Catalogue No.:PA 20 02600
(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester
Catalogue No.:PA 20 02610
1,3-Benzodioxole
Catalogue No.:PA 20 02620
Molecular Formula : C7H6O2
Molecular Weight : 122.12
5-Methylbenzo[d][1,3]dioxole
Catalogue No.:PA 20 02630
Molecular Formula : C8H8O2
Molecular Weight : 136.15
Tadalafil and Lactose Mixture
Catalogue No.:PA 20 02640
Molecular Formula : C34H41N3O15
Molecular Weight : 731.7
5-(1,3-Benzodioxol-5-yl)-1-piperidin-1-ylpentan-1-one
Catalogue No.:PA 20 02650
Molecular Formula : C17H23NO3
Molecular Weight : 289.36
(6R)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-7-((3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
Catalogue No.:PA 20 02660
Molecular Formula : C28H29N3O9
Molecular Weight : 551.54
(6R)-6-(Benzo[d][1,3]dioxol-5-yl)-7-((3R,4S,6R)-3,4-bis(2-hydroxypropoxy)-6-((2-hydroxypropoxy)methyl)-5-(((3R,4S,5S,6R)-3,4,5-tris(2-hydroxypropoxy)-6-((2-hydroxypropoxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
Catalogue No.:PA 20 02670
Molecular Formula : C55H81N3O21
Molecular Weight : 1120.24
(6R)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-7-((3R,4S,5S,6R)-3,4,5-tris(2-hydroxypropoxy)-6-((2-hydroxypropoxy)methyl)tetrahydro-2H-pyran-2-yl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
Catalogue No.:PA 20 02680
Molecular Formula : C40H53N3O13
Molecular Weight : 783.86
(6R)-6-(benzo[d][1,3]dioxol-5-yl)-2,7-dimethyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
Catalogue No.:PA 20 02690
Molecular Formula : C23H21N3O4
Molecular Weight : 403.43
(6R)-6-(Benzo[d][1,3]dioxol-5-yl)-7-(hydroxymethyl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
Catalogue No.:PA 20 02700
Molecular Formula : C23H21N3O5
Molecular Weight : 419.43
(6R)-6-(Benzo[d][1,3]dioxol-5-yl)-7-(hydroxy(5-(hydroxymethyl)furan-2-yl)methyl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
Catalogue No.:PA 20 02710
Molecular Formula : C28H25N3O7
Molecular Weight : 515.51
N-Butyl Nortadalafil-d9
Catalogue No.:PA STI 016650
Molecular Formula : C25H16D9N3O4
Molecular Weight : 440.54
2-Hydroxypropyl-d6 Nortadalafil
Catalogue No.:PA STI 051350
Molecular Formula : C24H17D6N3O5
Molecular Weight : 439.49
N-Octyl Nortadalafil-d17
Catalogue No.:PA STI 069740
Molecular Formula : C29H16D17N3O4
Molecular Weight : 504.69
ent-Tadalafil-d3
Catalogue No.:PA STI 080740
Molecular Formula : C22H16D3N3O4
Molecular Weight : 392.42
Tadalafil-d3
Catalogue No.:PA STI 080750
cis-Tadalafil-d3
Catalogue No.:PA STI 080760
cis-ent-Tadalafil-d3
Catalogue No.:PA STI 080770
(1R,3R)-1-(Benzo[d][1,3]dioxol-5-yl)-2,9-bis(2-chloroacetyl)-N-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide
Catalogue No.:PA 20 02740
Molecular Formula : C24H21Cl2N3O5
Molecular Weight : 502.35
(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-7-(2-chloroacetyl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Catalogue No.:PA 20 02750
Molecular Formula : C24H20ClN3O5
Molecular Weight : 465.89
Tadalafil (Y0001417)
Catalogue No.:PA EPY0001417
Molecular Formula : NA
Molecular Weight : NA
Catalogue No.:PA USP1642879
Molecular Formula :
(1R,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 02760
(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide
Catalogue No.:PA 20 0021002
Molecular Formula : C22H20ClN3O4
Molecular Weight : 425.87
Desmethylene Tadalafil
Catalogue No.:PA 20 0021003
Molecular Formula : C21H19N3O4
Molecular Weight : 377.4
N-Octyl Nortadalafil
Catalogue No.:PA 20 0021004
Molecular Formula : C29H33N3O4
Molecular Weight : 487.6
(2R)-Methyl 2-amino-3-(3H-indol-3-yl)propanoate hydrochloride
Catalogue No.:PA 20 0021005
Molecular Formula : C12H15ClN2O2
Molecular Weight : 254.71
(6S,12aS)-6-(3,4-Dihydroxyphenyl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Catalogue No.:PA 20 0021006
(6R,12aS)-6-(3,4-Dihydroxyphenyl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Catalogue No.:PA 20 0021007
Nortadalafil
Catalogue No.:PA 20 0021008
Molecular Formula : C21H17N3O4
Molecular Weight : 375.38
Tadalafil (IPRS/113/15) - from IPC
Catalogue No.:PA IPRS 113 15
(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
Catalogue No.:PA 20 0021010
Molecular Formula : C20H19ClN2O4
Molecular Weight : 386.83
(2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(2-methoxy-4-((6R,12aR)-2-methyl-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-6-yl)phenoxy)tetrahydro-2H-pyran-2-carboxylic Acid
Catalogue No.:PA 20 0021011
Molecular Formula : C28H29N3O10
Molecular Weight : 567.55
(6R,12aR)-6-(4-Hydroxy-3-methoxyphenyl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Catalogue No.:PA 20 0021012
Molecular Formula : C22H21N3O4
Molecular Weight : 391.43
1,3-Benzodioxole-5-glycolic Acid
Catalogue No.:PA 20 0021013
Molecular Formula : C9H8O5
Molecular Weight : 196.16
N-Nitroso Tadalafil
Catalogue No.:PA 20 0021014
Molecular Formula : C22H18N4O5
Molecular Weight : 418.41
(1R,3R)-1-(Benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide
Catalogue No.:PA 20 0021015
Molecular Formula : C19H17N3O3
Molecular Weight : 335.36
N-Desmethyl ent-Tadalafil
Catalogue No.:PA 20 0021016
Methyl (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-9-nitroso-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 0021017
Molecular Formula : C20H17N3O5
Molecular Weight : 379.37
Methyl (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-2-nitroso-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 0021018
Methyl (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-2,9-dinitroso-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 0021019
Molecular Formula : C20H16N4O6
Molecular Weight : 408.37
Methyl (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-9-nitroso-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 0021020
Molecular Formula : C22H18ClN3O6
Molecular Weight : 455.85
(6bR,12R)-12-(Benzo[d][1,3]dioxol-5-yl)-12a-hydroxy-8-methyl-6a,6b,8,9,12,12a-hexahydropyrazino[1',2':1,2]pyrrolo[3,4-c]quinoline-6,7,10(5H)-trione
Catalogue No.:PA 20 0021021
Molecular Weight : 421.41
(6R,12bR)-6-(Benzo[d][1,3]dioxol-5-yl)-12-hydroxy-2-methyl-2,3,6,12b-tetrahydropyrazino[1',2':1,5]pyrrolo[3,4-b]quinoline-1,4-dione
Catalogue No.:PA 20 0021022
Tadalafil Hydroxypiperidone
Catalogue No.:PA 20 0021023
(1R,3R)-1-(Benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Hydrochloride
Catalogue No.:PA 20 0021024
Molecular Formula : C19H17ClN2O4
Molecular Weight : 372.81
(1R,3R)-1-(Benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid
Catalogue No.:PA 20 0021025
Molecular Formula : C21H17ClN2O5
Molecular Weight : 412.83
Tadalafil 13CD3
Catalogue No.:PA STI 089475
Molecular Formula : C2113CH16D3N3O4
Molecular Weight : 393.42
N-Desmethyl-N-cyclopentyl Tadalafil
Catalogue No.:PA 20 0021026
Molecular Formula : C26H25N3O4
Molecular Weight : 443.5
(1R,3R)-1-(Benzo[d][1,3]dioxol-5-yl)-N-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide
Catalogue No.:PA 20 0021027
Molecular Formula : C20H19N3O3
Molecular Weight : 349.39
(1S,3R)-1-(Benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-N-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide
Catalogue No.:PA 20 0021028
Tadalafil (IPRST029)
Catalogue No.:PA IPRST029
Methyl 1-(benzo[d][1,3]dioxol-5-yl)-9H-pyrido[3,4-b]indole-3-carboxylate
Catalogue No.:PA 20 0021029
Molecular Formula : C20H14N2O4
Molecular Weight : 346.34
(1R,3R)-1-(Benzo[d][1,3]dioxol-5-yl)-2-nitroso-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid
Catalogue No.:PA 20 0021031
Molecular Formula : C19H15N3O5
Molecular Weight : 365.35
(1R,3R)-1-(Benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid
Catalogue No.:PA 20 0021032
Molecular Formula : C19H16N2O4
Molecular Weight : 336.35
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