Tacrolimus Monohydrate-impurities | Pharmaffiliates

tacrolimus monohydrate and its Impurities

A monohydrate salt of Tacrolimus, which is a macrolide lactone, used as an immunosupressant drug. Tacrolimus is a macrolide calcineurin inhibitor used mainly after allogeneic organ transplant to lower the risk of organ rejection. Topical ointment is used to treat severe cases of atopic dermatitis (eczema)Reference standards of Tacrolimus Monohydrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 8 results for tacrolimus monohydrate Impurities
PA 20 01000

Tacrolimus Monohydrate - API Standards

Tacrolimus Monohydrate


  • Catalogue No.:PA 20 01000

  • CAS :

    109581-93-3

  • Molecular Formula : C44H71NO13

  • Molecular Weight : 822.03

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PA 20 01040

Tacrolimus - Impurity D

(1R,9S,12S,13R,14S,17S,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone


  • Catalogue No.:PA 20 01040

  • CAS :

    129212-35-7

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.02

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PA 20 01540

Tacrolimus - Impurity A

Ascomycin


  • Catalogue No.:PA 20 01540

  • CAS :

    104987-12-4

  • Molecular Formula : C43H69NO12

  • Molecular Weight : 792.01

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PA 20 01510

Tacrolimus Monohydrate - Impurity E

(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R, 3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27- tetramethyl-17-propyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone


  • Catalogue No.:PA 20 01510

  • CAS :

    104987-30-6

  • Molecular Formula : C44H71NO12

  • Molecular Weight : 806.03

PA 20 01700

Tacrolimus Monohydrate - Impurity H

(1E,3S,4R,5S,8R,9E,12S,14S)-5-Hydroxy-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-14-methoxy-14-[(2R,3S,5R)-3-methoxy-5-methyl-6-oxooxan-2-yl]-2,4,10,12-tetramethyl-7-oxo-8-(prop-2-en-1-yl)tetradeca-1,9-dien-3-yl(2S)-1-formylpiperidine-2-carboxylate


  • Catalogue No.:PA 20 01700

  • CAS :

    143210-33-7

  • Molecular Formula : C43H69NO11

  • Molecular Weight : 776.02

PA 20 0010020

Tacrolimus monohydrate - Impurity B

(1S,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-17-Ethyl-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone,


  • Catalogue No.:PA 20 0010020

  • CAS :

    NA

  • Molecular Formula : C43H69NO12

  • Molecular Weight : 792.02

PA 20 0010060

Tacrolimus Monohydrate - Impurity F

(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,15-Dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,11,12,13,14,15,16,17,18,24,25,26,26a- hexadecahydro-7H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,19,20,21(8H,23H)-pentone


  • Catalogue No.:PA 20 0010060

  • CAS :

    1393890-33-9

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

PA 20 0010030

Tacrolimus Monohydrate - Impurity C

(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,21,27-trimethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone


  • Catalogue No.:PA 20 0010030

  • CAS :

    NA

  • Molecular Formula : C43H67NO12

  • Molecular Weight : 790