Spironolactone-Impurities | Pharmaffiliates

spironolactone and its Impurities

Spironolactone is used for the treatment of heart failures and kidney diseases. It is metabolised in liver and major metabolites of spironolactone are 7α-TMS,6β-OH-7α-TMS and canrenone,. Reference standards of Spironolactone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 43 results for spironolactone Impurities
PA 19 18000

Spironolactone

Spironolactone


  • Catalogue No.:PA 19 18000

  • CAS :

    52-01-7

  • Molecular Formula : C24H32O4S

  • Molecular Weight : 416.57

PA 19 18010

Spironolactone - Impurity A

Δ20-Spironolactone


  • Catalogue No.:PA 19 18010

  • CAS :

    132458-33-4

  • Molecular Formula : C24H30O4S

  • Molecular Weight : 414.56

PA 19 18030

Spironolactone - Impurity C

Aldone


  • Catalogue No.:PA 19 18030

  • CAS :

    976-70-5

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.47

PA 19 18040

Spironolactone - Impurity D

Disulfanyl Spironolactone


  • Catalogue No.:PA 19 18040

  • CAS :

    NA

  • Molecular Formula : C24H32O4S2

  • Molecular Weight : 448.64

PA 19 18050

Spironolactone - Impurity E

7β-Spironolactone


  • Catalogue No.:PA 19 18050

  • CAS :

    33784-05-3

  • Molecular Formula : C24H32O4S

  • Molecular Weight : 416.57

PA 19 18060

Spironolactone - Impurity F

Canrenone


  • Catalogue No.:PA 19 18060

  • CAS :

    976-71-6

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

PA 19 18090

Spironolactone - Impurity I

S-[17α-(Ethoxymethyl)-17-hydroxy-3-oxoandrost-4-en-7α-yl] Ethanethioate


  • Catalogue No.:PA 19 18090

  • CAS :

    NA

  • Molecular Formula : C24H36O4S

  • Molecular Weight : 420.61

PA 19 18510

(2'R,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'(4'H)-one

(2'R,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'(4'H)-one


  • Catalogue No.:PA 19 18510

  • CAS :

    NA

  • Molecular Formula : C23H32O3

  • Molecular Weight : 356.5

PA 19 18520

(2'S,8R,9S,10R,13S,14S)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione

(2'S,8R,9S,10R,13S,14S)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione


  • Catalogue No.:PA 19 18520

  • CAS :

    NA

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

PA STI 004940

Althiazide-d5

Althiazide-d5


  • Catalogue No.:PA STI 004940

  • CAS :

    1329837-71-9

  • Molecular Formula : C11H9D5ClN3O4S3

  • Molecular Weight : 388.93

PA STI 079750

Spironolactone-d6 (Major)

Spironolactone-d6 (Major)


  • Catalogue No.:PA STI 079750

  • CAS :

    NA

  • Molecular Formula : C24H26D6O4S

  • Molecular Weight : 422.61

PA STI 079760

Spironolactone-d3

Spironolactone-d3


  • Catalogue No.:PA STI 079760

  • CAS :

    NA

  • Molecular Formula : C24H29D3O4S

  • Molecular Weight : 419.59

PA STI 082790

7α-Thiomethyl Spironolactone-d7 (Major)

7α-Thiomethyl Spironolactone-d7 (Major)


  • Catalogue No.:PA STI 082790

  • CAS :

    NA

  • Molecular Formula : C23H25D7O3S

  • Molecular Weight : 395.61

PA 19 18020

Spironolactone - Impurity B

4-Bromospironolactone


  • Catalogue No.:PA 19 18020

  • CAS :

    NA

  • Molecular Formula : C24H31BrO4S

  • Molecular Weight : 495.47

PA 19 18070

Spironolactone - Impurity G

6β-Hydroxy-spironolactone


  • Catalogue No.:PA 19 18070

  • CAS :

    880106-10-5

  • Molecular Formula : C24H32O5S

  • Molecular Weight : 432.58

PA 19 18080

Spironolactone - Impurity H

(2'S)-Spiro[androst-4,6-diene-17,2'-oxiran]-3-one


  • Catalogue No.:PA 19 18080

  • CAS :

    53866-24-3

  • Molecular Formula : C20H26O2

  • Molecular Weight : 298.43

PA ICRS49241

Spironolactone (ICRS49241)


  • Catalogue No.:PA ICRS49241

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA JP0217

Spironolactone (JP 0217)

Spironolactone (JP 0217)


  • Catalogue No.:PA JP0217

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPS1200000

Spironolactone (S1200000)

Spironolactone (S1200000)


  • Catalogue No.:PA EPS1200000

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPY0001295

Spironolactone for system suitability (Y0001295)

Spironolactone for system suitability (Y0001295)


  • Catalogue No.:PA EPY0001295

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1619006

Spironolactone (1619006)

Spironolactone (1619006)


  • Catalogue No.:PA USP1619006

  • CAS :

    52-01-7

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1619017

Spironolactone Related Compound A (Canrenone (3-Oxo-17-alpha-pregna-4,6-diene-21, 17-carbolactone)) (1619017)

Spironolactone Related Compound A (Canrenone (3-Oxo-17-alpha-pregna-4,6-diene-21, 17-carbolactone)) (1619017)


  • Catalogue No.:PA USP1619017

  • CAS :

    976-71-6

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1619028

Spironolactone Related Compound B ((2'R)-7alpha-(Acetylthio)-5'H-spiro[androst-4-ene-17,2'-furan]-3 (1619028)

Spironolactone Related Compound B ((2'R)-7alpha-(Acetylthio)-5'H-spiro[androst-4-ene-17,2'-furan]-3 (1619028)


  • Catalogue No.:PA USP1619028

  • CAS :

    132458-33-4

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1619039

Spironolactone Related Compound C ((2'R)-3',4'-Dihydro-5'H-spiro[androst-4-ene-17,2'-furan]-3,5'-di (1619039)

Spironolactone Related Compound C ((2'R)-3',4'-Dihydro-5'H-spiro[androst-4-ene-17,2'-furan]-3,5'-di (1619039)


  • Catalogue No.:PA USP1619039

  • CAS :

    976-70-5

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1619040

Spironolactone Related Compound D ((2'R)-7alpha-(Acetyldisulfanyl)-3',4'-dihydro-5'H-spiro[androst- (1619040)

Spironolactone Related Compound D ((2'R)-7alpha-(Acetyldisulfanyl)-3',4'-dihydro-5'H-spiro[androst- (1619040)


  • Catalogue No.:PA USP1619040

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1619051

Spironolactone Epimer Mixture (7-Epispironolactone approximately 56% and Spironolactone approximate (1619051)

Spironolactone Epimer Mixture (7-Epispironolactone approximately 56% and Spironolactone approximate (1619051)


  • Catalogue No.:PA USP1619051

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1619094

Spironolactone Related Compound I (S-[17alpha-(Ethoxymethyl)-17-hydroxy-3-oxoandrost-4-en-7alpha-yl (1619094)

Spironolactone Related Compound I (S-[17alpha-(Ethoxymethyl)-17-hydroxy-3-oxoandrost-4-en-7alpha-yl (1619094)


  • Catalogue No.:PA USP1619094

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA BP306RB

spironolactone (306RB)

spironolactone (306RB)


  • Catalogue No.:PA BP306RB

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 19 18530

Spironolactone Epimer Mixture

Spironolactone Epimer Mixture


  • Catalogue No.:PA 19 18530

  • CAS :

    NA

  • Molecular Formula : C24H32O4S

  • Molecular Weight : 416.58

PAI 19 018001

(8R,9S,10R,13S,14S,17S)-17-Hydroxy-17-(3-hydroxyprop-1-yn-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

(8R,9S,10R,13S,14S,17S)-17-Hydroxy-17-(3-hydroxyprop-1-yn-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one


  • Catalogue No.:PAI 19 018001

  • CAS :

    55542-26-2

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.48

PAI 19 018002

(8R,9S,10R,13S,14S,17R)-17-Hydroxy-17-(3-hydroxyprop-1-en-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

(8R,9S,10R,13S,14S,17R)-17-Hydroxy-17-(3-hydroxyprop-1-en-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one


  • Catalogue No.:PAI 19 018002

  • CAS :

    NA

  • Molecular Formula : C22H32O3

  • Molecular Weight : 344.5

PAI 19 018003

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione


  • Catalogue No.:PAI 19 018003

  • CAS :

    52845-59-7

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

PAI 19 018004

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione


  • Catalogue No.:PAI 19 018004

  • CAS :

    NA

  • Molecular Formula : C22H26O3

  • Molecular Weight : 338.45

PAI 19 018005

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate


  • Catalogue No.:PAI 19 018005

  • CAS :

    NA

  • Molecular Formula : C24H34O4

  • Molecular Weight : 386.53

PAI 19 018006

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate


  • Catalogue No.:PAI 19 018006

  • CAS :

    NA

  • Molecular Formula : C24H36O4

  • Molecular Weight : 388.55

PAI 19 018007

(3S,8R,9S,10R,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one

(3S,8R,9S,10R,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one


  • Catalogue No.:PAI 19 018007

  • CAS :

    NA

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.48

PAI 19 018008

(3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]androst-5-en-17-one

(3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]androst-5-en-17-one


  • Catalogue No.:PAI 19 018008

  • CAS :

    42151-23-5

  • Molecular Formula : C25H42O2Si

  • Molecular Weight : 402.69

PAI 19 018009

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate


  • Catalogue No.:PAI 19 018009

  • CAS :

    NA

  • Molecular Formula : C30H48O4Si

  • Molecular Weight : 500.8

PAI 19 018010

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate


  • Catalogue No.:PAI 19 018010

  • CAS :

    NA

  • Molecular Formula : C30H50O4Si

  • Molecular Weight : 502.81

PAI 19 018011

(3S,8R,9S,10R,13S,14S,17R)-3-((tert-Butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one

(3S,8R,9S,10R,13S,14S,17R)-3-((tert-Butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one


  • Catalogue No.:PAI 19 018011

  • CAS :

    NA

  • Molecular Formula : C28H44O3Si

  • Molecular Weight : 456.74

PA 19 0181000

7α-Thiomethyl spironolactone

7α-Thiomethyl spironolactone


  • Catalogue No.:PA 19 0181000

  • CAS :

    38753-77-4

  • Molecular Formula : C23H32O3S

  • Molecular Weight : 388.57

PA 19 0181001

7α-Thio spironolactone

7α-Thio spironolactone


  • Catalogue No.:PA 19 0181001

  • CAS :

    38753-76-3

  • Molecular Formula : C22H30O3S

  • Molecular Weight : 374.54

PA IPRS 36 18

Spironolactone (IPRS/36/18)-from IPC

Spironolactone (IPRS/36/18)-from IPC


  • Catalogue No.:PA IPRS 36 18

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA