A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
4-Chloro-3-(trifluoromethyl)phenyl Isocyanate
Catalogue No.:PA 46 17580
CAS :
Molecular Formula : C8H3ClF3NO
Molecular Weight : 221.56
Flucofuron
Catalogue No.:PA 46 17610
Molecular Formula : C15H8Cl2F6N2O
Molecular Weight : 417.13
Sorafenib
Catalogue No.:PA 46 17000
Molecular Formula : C21H16ClF3N4O3
Molecular Weight : 464.82
2-(4-(4-(3-(2-Chloro-3-(Trifluoromethyl)phenyl)ureido)Phenoxy)-6-Methylpicolinamido)-4-Methylbenzenesulfonic Acid
Catalogue No.:PA 46 17510
Molecular Formula : C28H22ClF3N4O6S
Molecular Weight : 635.01
Sorafenib N-Oxide
Catalogue No.:PA 19 69510
Molecular Formula : C21H16ClF3N4O4
Molecular Weight : 480.82
4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride
Catalogue No.:PA 19 69520
Molecular Formula : C7H8Cl2N2O
Molecular Weight : 207.06
Sorafenib β-D-Glucuronide
Catalogue No.:PA 19 69540
Molecular Formula : C27H24ClF3N4O9
Molecular Weight : 640.95
Sorafenib Hemi-Tosylate
Catalogue No.:PA 19 69550
Molecular Formula : C21H16ClF3N4O3 .1/2 C7H8O3S
Molecular Weight : 464.83
Sorafenib-d3
Catalogue No.:PA STI 079660
Molecular Formula : C21H13D3ClF3N4O3
Molecular Weight : 467.84
N-Methyl-4-(4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)picolinamide
Catalogue No.:PA 46 17590
Molecular Formula : C20H19N5O3
Molecular Weight : 377.4
Ethyl (4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate
Catalogue No.:PA 46 17600
Molecular Formula : C16H17N3O4
Molecular Weight : 315.33
4-Chloro-N-methylpyridine-2-carboxamide
Catalogue No.:PA 46 17620
Molecular Formula : C7H7ClN2O
Molecular Weight : 170.6
Catalogue No.:PA IPIPRS 109 14
Molecular Formula :
Molecular Weight : NA
N-Desmethyl Sorafenib
Catalogue No.:PA 46 17630
Molecular Formula : C20H14ClF3N4O3
Molecular Weight : 450.8
1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea
Catalogue No.:PA 46 17640
Molecular Formula : C25H14Cl2F4N2O
Molecular Weight : 505.29
Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib
Catalogue No.:PA 46 17660
Molecular Formula : C27H23N5O6
Molecular Weight : 513.51
4-(Trifluoromethoxy)phenyl Isothiocyanate
Catalogue No.:PA 46 17650
Molecular Formula : C8H4F3NOS
Molecular Weight : 219.18
Sorafenib-13C,d3
Catalogue No.:PA STI 079661
Molecular Formula : C2013CH13D3ClF3N4O3
Molecular Weight : 468.84
4-(4-Aminophenoxy)-N-ethylpicolinamide
Catalogue No.:PA 46 17670
Molecular Formula : C14H15N3O2
Molecular Weight : 257.29
4-(Hydroxyamino)phenol
Catalogue No.:PA 46 0171000
Molecular Formula : C6H7NO2
Molecular Weight : 125.13
Sorafenib Hydroxydemethylamine
Catalogue No.:PA 46 0171001
Molecular Formula : C20H13ClF3N3O4
Molecular Weight : 451.79
4-(4-Aminophenoxy)picolinic acid
Catalogue No.:PA 46 0171002
Molecular Formula : C12H10N2O3
Molecular Weight : 230.22
4-(3-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide
Catalogue No.:PA 19 0691000
N-Desmethyl Sorafenib (Pyridine)-N-oxide
Catalogue No.:PA 19 0691001
Molecular Formula : C20H14ClF3N4O4
Molecular Weight : 466.8
1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea
Catalogue No.:PA 19 0691002
Molecular Formula : C14H10ClF3N2O2
Molecular Weight : 330.69
2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene
Catalogue No.:PA 46 0171003
N-Methyl-4-phenoxypicolinamide
Catalogue No.:PA 46 0171004
Molecular Formula : C13H12N2O2
Molecular Weight : 228.25
Phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate
Catalogue No.:PA 46 0171005
Molecular Formula : C14H9ClF3NO2
Molecular Weight : 315.68
1-(4-Chloro-3-(trifluoromethyl)phenyl)urea
Catalogue No.:PA 46 0171006
Molecular Formula : C8H6ClF3N2O
Molecular Weight : 238.59
6-Chloro-N-methyl-2-pyridinecarboxamide
Catalogue No.:PA 46 0171007
N-Methylpicolinamide hydrochloride
Catalogue No.:PA 46 0171008
Molecular Formula : C7H9ClN2O
Molecular Weight : 172.61
Phenyl (2-chloro-3-(trifluoromethyl)phenyl)carbamate
Catalogue No.:PAI 19 069001
N-(2-Chloro-3-(trifluoromethyl)phenyl)-O-pivaloylhydroxylamine
Catalogue No.:PAI 19 069002
Molecular Formula : C12H13ClF3NO2
Molecular Weight : 295.69
Phenyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate
Catalogue No.:PAI 46 017001
Molecular Formula : C20H17N3O4
Molecular Weight : 363.37
4-(4-(3-(4-Chloro-3(trifluoromethyl)phenyl)ureido)phenox yl)-n-ethylpicolinamide
Catalogue No.:PA 46 0171010
Molecular Formula : C22H18ClF3N4O3
Molecular Weight : 478.86
N-Methyl-4-(4-ureidophenoxy)picolinamide
Catalogue No.:PA 46 0171009
Molecular Formula : C14H14N4O3
Molecular Weight : 286.29
4-Chloro-N-methyl-N-(2-(methylcarbamoyl)pyridin-4-yl)picolinamide
Catalogue No.:PA 46 0171011
Molecular Formula : C14H13ClN4O2
Molecular Weight : 304.73
Methyl 4-(4-aminophenoxy)picolinate
Catalogue No.:PA 46 0171012
Molecular Formula : C13H12N2O3
Molecular Weight : 244.25
Sorafenib Carboxylic Acid Methyl Ester
Catalogue No.:PA 46 0171013
Molecular Formula : C21H15ClF3N3O4
Molecular Weight : 465.81
4,4'-((((Azanediylbis(carbonyl))bis(azanediyl))bis(4,1-phenylene))bis(oxy))bis(N-methylpicolinamide)
Catalogue No.:PA 46 0171014
Molecular Formula : C28H25N7O6
Molecular Weight : 555.55
1-(4-Ethoxy-3-(trifluoromethyl)phenyl)-3-(2-(3-(hydroxymethyl)piperidin-1-yl)ethyl)urea
Catalogue No.:PA 46 0171015
Molecular Formula : C18H26F3N3O3
Molecular Weight : 389.42
N-Methyl-4-(methylamino)picolinamide
Catalogue No.:PA 46 0171016
Molecular Formula : C8H11N3O
Molecular Weight : 165.2
4,6-Dichloro-N-methylpicolinamide
Catalogue No.:PA 46 0171017
Molecular Formula : C7H6Cl2N2O
Molecular Weight : 205.04
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