sorafenib and its Impurities

A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 45 results for sorafenib Impurities
PA 46 17000

Sorafenib

Sorafenib

  • Catalogue No.:PA 46 17000

  • CAS :

    284461-73-0

  • Molecular Formula : C21H16ClF3N4O3

  • Molecular Weight : 464.82

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PA 46 17510

2-(4-(4-(3-(2-Chloro-3-(Trifluoromethyl)phenyl)ureido)Phenoxy)-6-Methylpicolinamido)-4-Methylbenzenesulfonic Acid

2-(4-(4-(3-(2-Chloro-3-(Trifluoromethyl)phenyl)ureido)Phenoxy)-6-Methylpicolinamido)-4-Methylbenzenesulfonic Acid

  • Catalogue No.:PA 46 17510

  • CAS :

    NA

  • Molecular Formula : C28H22ClF3N4O6S

  • Molecular Weight : 635.01

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PA 19 69510

Sorafenib N-Oxide

Sorafenib N-Oxide

  • Catalogue No.:PA 19 69510

  • CAS :

    583840-03-3

  • Molecular Formula : C21H16ClF3N4O4

  • Molecular Weight : 480.82

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PA 19 69520

4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride

4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride

  • Catalogue No.:PA 19 69520

  • CAS :

    882167-77-3

  • Molecular Formula : C7H8Cl2N2O

  • Molecular Weight : 207.06

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PA 19 69540

Sorafenib β-D-Glucuronide

Sorafenib β-D-Glucuronide

  • Catalogue No.:PA 19 69540

  • CAS :

    1130164-93-0

  • Molecular Formula : C27H24ClF3N4O9

  • Molecular Weight : 640.95

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PA 19 69550

Sorafenib Hemi-Tosylate

Sorafenib Hemi-Tosylate

  • Catalogue No.:PA 19 69550

  • CAS :

    2056030-06-7

  • Molecular Formula : C21H16ClF3N4O3 .1/2 C7H8O3S

  • Molecular Weight : 464.83

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PA STI 079660

Sorafenib-d3

Sorafenib-d3

  • Catalogue No.:PA STI 079660

  • CAS :

    1130115-44-4

  • Molecular Formula : C21H13D3ClF3N4O3

  • Molecular Weight : 467.84

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PA 46 17580

4-Chloro-3-(trifluoromethyl)phenyl Isocyanate

4-Chloro-3-(trifluoromethyl)phenyl Isocyanate

  • Catalogue No.:PA 46 17580

  • CAS :

    327-78-6

  • Molecular Formula : C8H3ClF3NO

  • Molecular Weight : 221.56

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PA 46 17590

N-Methyl-4-(4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)picolinamide

N-Methyl-4-(4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)picolinamide

  • Catalogue No.:PA 46 17590

  • CAS :

    2004659-83-8

  • Molecular Formula : C20H19N5O3

  • Molecular Weight : 377.4

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PA 46 17600

Ethyl (4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

Ethyl (4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

  • Catalogue No.:PA 46 17600

  • CAS :

    2206827-12-3

  • Molecular Formula : C16H17N3O4

  • Molecular Weight : 315.33

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PA 46 17610

Flucofuron

Flucofuron

  • Catalogue No.:PA 46 17610

  • CAS :

    370-50-3

  • Molecular Formula : C15H8Cl2F6N2O

  • Molecular Weight : 417.13

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PA 46 17620

4-Chloro-N-methylpyridine-2-carboxamide

4-Chloro-N-methylpyridine-2-carboxamide

  • Catalogue No.:PA 46 17620

  • CAS :

    220000-87-3

  • Molecular Formula : C7H7ClN2O

  • Molecular Weight : 170.6

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PA IPIPRS 109 14

Sorafenib Tosylate (IPRS/109/14)-from IPC

  • Catalogue No.:PA IPIPRS 109 14

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

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PA 46 17630

N-Desmethyl Sorafenib

N-Desmethyl Sorafenib

  • Catalogue No.:PA 46 17630

  • CAS :

    284461-74-1

  • Molecular Formula : C20H14ClF3N4O3

  • Molecular Weight : 450.8

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PA 46 17640

1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea

1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea

  • Catalogue No.:PA 46 17640

  • CAS :

    2514724-45-7

  • Molecular Formula : C25H14Cl2F4N2O

  • Molecular Weight : 505.29

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PA 46 17660

Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib

Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib

  • Catalogue No.:PA 46 17660

  • CAS :

    2204442-52-2

  • Molecular Formula : C27H23N5O6

  • Molecular Weight : 513.51

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PA 46 17650

4-(Trifluoromethoxy)phenyl Isothiocyanate

4-(Trifluoromethoxy)phenyl Isothiocyanate

  • Catalogue No.:PA 46 17650

  • CAS :

    64285-95-6

  • Molecular Formula : C8H4F3NOS

  • Molecular Weight : 219.18

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PA STI 079661

Sorafenib-13C,d3

Sorafenib-13C,d3

  • Catalogue No.:PA STI 079661

  • CAS :

    1210608-86-8

  • Molecular Formula : C2013CH13D3ClF3N4O3

  • Molecular Weight : 468.84

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PA 46 17670

4-(4-Aminophenoxy)-N-ethylpicolinamide

4-(4-Aminophenoxy)-N-ethylpicolinamide

  • Catalogue No.:PA 46 17670

  • CAS :

    284462-82-4

  • Molecular Formula : C14H15N3O2

  • Molecular Weight : 257.29

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PA 46 0171000

4-(Hydroxyamino)phenol

4-(Hydroxyamino)phenol

  • Catalogue No.:PA 46 0171000

  • CAS :

    3505-87-1

  • Molecular Formula : C6H7NO2

  • Molecular Weight : 125.13

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PA 46 0171001

Sorafenib Hydroxydemethylamine

Sorafenib Hydroxydemethylamine

  • Catalogue No.:PA 46 0171001

  • CAS :

    1012058-78-4

  • Molecular Formula : C20H13ClF3N3O4

  • Molecular Weight : 451.79

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PA 46 0171002

4-(4-Aminophenoxy)picolinic acid

4-(4-Aminophenoxy)picolinic acid

  • Catalogue No.:PA 46 0171002

  • CAS :

    1012058-77-3

  • Molecular Formula : C12H10N2O3

  • Molecular Weight : 230.22

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PA 19 0691000

4-(3-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

4-(3-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

  • Catalogue No.:PA 19 0691000

  • CAS :

    284461-76-3

  • Molecular Formula : C21H16ClF3N4O3

  • Molecular Weight : 464.83

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PA 19 0691001

N-Desmethyl Sorafenib (Pyridine)-N-oxide

N-Desmethyl Sorafenib (Pyridine)-N-oxide

  • Catalogue No.:PA 19 0691001

  • CAS :

    583840-04-4

  • Molecular Formula : C20H14ClF3N4O4

  • Molecular Weight : 466.8

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PA 19 0691002

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea

  • Catalogue No.:PA 19 0691002

  • CAS :

    1129683-83-5

  • Molecular Formula : C14H10ClF3N2O2

  • Molecular Weight : 330.69

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PA 46 0171003

2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene

2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene

  • Catalogue No.:PA 46 0171003

  • CAS :

    88330-63-6

  • Molecular Formula : C8H3ClF3NO

  • Molecular Weight : 221.56

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PA 46 0171004

N-Methyl-4-phenoxypicolinamide

N-Methyl-4-phenoxypicolinamide

  • Catalogue No.:PA 46 0171004

  • CAS :

    2004659-85-0

  • Molecular Formula : C13H12N2O2

  • Molecular Weight : 228.25

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PA 46 0171005

Phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate

Phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate

  • Catalogue No.:PA 46 0171005

  • CAS :

    871555-75-8

  • Molecular Formula : C14H9ClF3NO2

  • Molecular Weight : 315.68

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PA 46 0171006

1-(4-Chloro-3-(trifluoromethyl)phenyl)urea

1-(4-Chloro-3-(trifluoromethyl)phenyl)urea

  • Catalogue No.:PA 46 0171006

  • CAS :

    343247-69-8

  • Molecular Formula : C8H6ClF3N2O

  • Molecular Weight : 238.59

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PA 46 0171007

6-Chloro-N-methyl-2-pyridinecarboxamide

6-Chloro-N-methyl-2-pyridinecarboxamide

  • Catalogue No.:PA 46 0171007

  • CAS :

    845306-04-9

  • Molecular Formula : C7H7ClN2O

  • Molecular Weight : 170.6

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PA 46 0171008

N-Methylpicolinamide hydrochloride

N-Methylpicolinamide hydrochloride

  • Catalogue No.:PA 46 0171008

  • CAS :

    NA

  • Molecular Formula : C7H9ClN2O

  • Molecular Weight : 172.61

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PAI 19 069001

Phenyl (2-chloro-3-(trifluoromethyl)phenyl)carbamate

Phenyl (2-chloro-3-(trifluoromethyl)phenyl)carbamate

  • Catalogue No.:PAI 19 069001

  • CAS :

    2518227-67-1

  • Molecular Formula : C14H9ClF3NO2

  • Molecular Weight : 315.68

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PAI 19 069002

N-(2-Chloro-3-(trifluoromethyl)phenyl)-O-pivaloylhydroxylamine

N-(2-Chloro-3-(trifluoromethyl)phenyl)-O-pivaloylhydroxylamine

  • Catalogue No.:PAI 19 069002

  • CAS :

    NA

  • Molecular Formula : C12H13ClF3NO2

  • Molecular Weight : 295.69

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PAI 46 017001

Phenyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

Phenyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

  • Catalogue No.:PAI 46 017001

  • CAS :

    1129683-92-6

  • Molecular Formula : C20H17N3O4

  • Molecular Weight : 363.37

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PA 46 0171010

4-(4-(3-(4-Chloro-3(trifluoromethyl)phenyl)ureido)phenox yl)-n-ethylpicolinamide

4-(4-(3-(4-Chloro-3(trifluoromethyl)phenyl)ureido)phenox yl)-n-ethylpicolinamide

  • Catalogue No.:PA 46 0171010

  • CAS :

    284461-82-1

  • Molecular Formula : C22H18ClF3N4O3

  • Molecular Weight : 478.86

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PA 46 0171009

N-Methyl-4-(4-ureidophenoxy)picolinamide

N-Methyl-4-(4-ureidophenoxy)picolinamide

  • Catalogue No.:PA 46 0171009

  • CAS :

    1129683-88-0

  • Molecular Formula : C14H14N4O3

  • Molecular Weight : 286.29

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PA 46 0171011

4-Chloro-N-methyl-N-(2-(methylcarbamoyl)pyridin-4-yl)picolinamide

4-Chloro-N-methyl-N-(2-(methylcarbamoyl)pyridin-4-yl)picolinamide

  • Catalogue No.:PA 46 0171011

  • CAS :

    NA

  • Molecular Formula : C14H13ClN4O2

  • Molecular Weight : 304.73

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PA 46 0171012

Methyl 4-(4-aminophenoxy)picolinate

Methyl 4-(4-aminophenoxy)picolinate

  • Catalogue No.:PA 46 0171012

  • CAS :

    757251-59-5

  • Molecular Formula : C13H12N2O3

  • Molecular Weight : 244.25

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PA 46 0171013

Sorafenib Carboxylic Acid Methyl Ester

Sorafenib Carboxylic Acid Methyl Ester

  • Catalogue No.:PA 46 0171013

  • CAS :

    573673-43-5

  • Molecular Formula : C21H15ClF3N3O4

  • Molecular Weight : 465.81

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PA 46 0171014

4,4'-((((Azanediylbis(carbonyl))bis(azanediyl))bis(4,1-phenylene))bis(oxy))bis(N-methylpicolinamide)

4,4'-((((Azanediylbis(carbonyl))bis(azanediyl))bis(4,1-phenylene))bis(oxy))bis(N-methylpicolinamide)

  • Catalogue No.:PA 46 0171014

  • CAS :

    2206827-18-9

  • Molecular Formula : C28H25N7O6

  • Molecular Weight : 555.55

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PA 46 0171015

1-(4-Ethoxy-3-(trifluoromethyl)phenyl)-3-(2-(3-(hydroxymethyl)piperidin-1-yl)ethyl)urea

1-(4-Ethoxy-3-(trifluoromethyl)phenyl)-3-(2-(3-(hydroxymethyl)piperidin-1-yl)ethyl)urea

  • Catalogue No.:PA 46 0171015

  • CAS :

    1567296-47-2

  • Molecular Formula : C18H26F3N3O3

  • Molecular Weight : 389.42

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PA 46 0171016

N-Methyl-4-(methylamino)picolinamide

N-Methyl-4-(methylamino)picolinamide

  • Catalogue No.:PA 46 0171016

  • CAS :

    1065074-98-7

  • Molecular Formula : C8H11N3O

  • Molecular Weight : 165.2

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PA 46 0171017

4,6-Dichloro-N-methylpicolinamide

4,6-Dichloro-N-methylpicolinamide

  • Catalogue No.:PA 46 0171017

  • CAS :

    1379324-09-0

  • Molecular Formula : C7H6Cl2N2O

  • Molecular Weight : 205.04

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PA STI 089851

Sorafenib-D4

Sorafenib-D4

  • Catalogue No.:PA STI 089851

  • CAS :

    1207560-07-3

  • Molecular Formula : C21H12D4ClF3N4O3

  • Molecular Weight : 468.85

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PA EP Y0002233

Sorafenib Impurity H (Y0002233)

Sorafenib Impurity H (Y0002233)

  • Catalogue No.:PA EP Y0002233

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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