A recently approved nucleotide analog used in the treatment of hepatitis. Sofosbuvir works by inhibiting the hepatitis C NS5B protein. It is a a prodrug of its active antiviral agent GS-461203 Reference standards of Sofosbuvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Sofosbuvir
Catalogue No.:PA 19 51000
CAS :
Molecular Formula : C22H29FN3O9P
Molecular Weight : 529.45
Sofosbuvir Nucleoside Derivative
Catalogue No.:PA 19 51510
Molecular Formula : C10H13FN2O5
Molecular Weight : 260.22
Sofosbuvir Metabolite GS-566500
Catalogue No.:PA 19 51520
Molecular Formula : C13H19FN3O9P
Molecular Weight : 411.28
((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl dihydrogen Phosphate
Catalogue No.:PA 19 51530
Molecular Formula : C10H14FN2O8P
Molecular Weight : 340.2
Pentafluorophenol
Catalogue No.:PA 19 51540
Molecular Formula : C6HF5O
Molecular Weight : 184.06
N-(2-((Trimethylsilyl)oxy)pyrimidin-4-yl)benzamide
Catalogue No.:PA 19 51550
Molecular Formula : C14H17N3O2Si
Molecular Weight : 287.39
(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one
Catalogue No.:PA 19 51560
Molecular Formula : C6H9FO4
Molecular Weight : 164.13
((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl Benzoate
Catalogue No.:PA 19 51570
Molecular Formula : C20H17FO6
Molecular Weight : 372.34
[(2R,3R,4R,5R)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl]methyl Benzoate
Catalogue No.:PA 19 51580
Molecular Formula : C20H19FO6
Molecular Weight : 374.36
[(2R,3R,4R,5S)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl]methyl Benzoate
Catalogue No.:PA 19 51590
[(2R,3R,4R,5R)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl]methyl Benzoate
Catalogue No.:PA 19 51600
Molecular Formula : C20H18ClFO5
Molecular Weight : 392.81
[(2R,3R,4R,5S)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl]methyl Benzoate
Catalogue No.:PA 19 51610
(2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate
Catalogue No.:PA 19 51620
Molecular Formula : C31H26FN3O7
Molecular Weight : 571.55
((2R,3R,4R,5R)-3-(Benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl Benzoate
Catalogue No.:PA 19 51630
Molecular Formula : C24H21FN2O7
Molecular Weight : 468.43
1-((2S,3S,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 19 51640
1-((2S,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 19 51650
1-((2R,3R,4R,5R)-3-Chloro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 19 51660
Molecular Formula : C10H13ClN2O5
Molecular Weight : 276.67
(1R,2S)-1-((R)-2,2-Dimethyl-1,3-dioxolan-4-yl)-3-ethoxy-2-fluoro-2-methyl-3-oxopropyl Sulfate
Catalogue No.:PA 19 51670
Molecular Formula : C11H19FO8S
Molecular Weight : 330.33
(4S,5R)-Ethyl 5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-methyl-1,3,2-dioxathiolane-4-carboxylate 2,2-dioxide
Catalogue No.:PA 19 51680
Molecular Formula : C11H18O8S
Molecular Weight : 310.32
(2S,3R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate
Catalogue No.:PA 19 51690
Molecular Formula : C11H20O6
Molecular Weight : 248.27
(S,E)-Ethyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylacrylate
Catalogue No.:PA 19 51700
Molecular Formula : C11H18O4
Molecular Weight : 214.26
(R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde
Catalogue No.:PA 19 51710
Molecular Formula : C6H10O3
Molecular Weight : 130.14
Mixture of (Pentafluorophenol, Sofosbuvir-14-ethyl impurity, Sofosbuvir-14, And n-Propyl Sofosbuvir-14)
Catalogue No.:PA 19 51720
Molecular Formula : C59H50F20N3O16P3
Molecular Weight : 1529.93
Mixture of (Sofosbuvir-14 And L-Rp-Sofosbuvir-14)
Catalogue No.:PA 19 51730
Molecular Formula : C36H34F10N2O10P2
Molecular Weight : 906.59
Mixture of (Pentafluorophenol, Sofosbuvir, Rp-Sofosbuvir, n-Propyl Sofosbuvir)
Catalogue No.:PA 19 51740
Molecular Formula : C72H88F8N9O28P3
Molecular Weight : 1772.42
Sofosbuvir-12 And Sofosbuvir-12 Anomer
Catalogue No.:PA 19 51750
Molecular Formula : C62H52F2N6O14
Molecular Weight : 1143.1
Mixture of (Sofosbuvir-7 Sofosbuvir-7 Anomer)
Catalogue No.:PA 19 51760
Molecular Formula : C20H26F2N4O10
Molecular Weight : 520.44
Sofosbuvir (R)-Phosphate
Catalogue No.:PA 19 51770
D-Alanine Sofosbuvir
Catalogue No.:PA 19 51780
Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-Dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 51790
(R)-Isopropyl 2-(((R)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Catalogue No.:PA 19 51800
(S)-Sofosbuvir Pentafluorophenoxy Analogue
Catalogue No.:PA 19 51810
Molecular Formula : C18H17F5NO5P
Molecular Weight : 453.3
Chloro Sofosbuvir
Catalogue No.:PA 19 51820
Molecular Formula : C22H29ClN3O9P
Molecular Weight : 545.91
Sofosbuvir 3',5'-Bis-(S)-phosphate
Catalogue No.:PA 19 51830
Molecular Formula : C34H45FN4O13P2
Molecular Weight : 798.69
Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]
Catalogue No.:PA 19 51840
((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl Phenyl Hydrogen Phosphate
Catalogue No.:PA 19 51850
Molecular Formula : C16H18FN2O8P
Molecular Weight : 416.29
Sofosbuvir α-Isomer
Catalogue No.:PA 19 51860
(2R,3S,4S,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
Catalogue No.:PA 19 51870
(S)-Isopropyl 2-(((S)-(((2S,3S,4S,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Catalogue No.:PA 19 51880
(R)-Isopropyl 2-(((R)-(((2S,3S,4S,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Catalogue No.:PA 19 51890
Sofosbuvir-13CD3
Catalogue No.:PA STI 079621
Molecular Formula : C2113CH26D3FN3O9P
Molecular Weight : 533.46
Sofosbuvir-d6
Catalogue No.:PA STI 079622
Molecular Formula : C22H23D6FN3O9P
Molecular Weight : 535.49
(S)-Ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;
Catalogue No.:PA 19 51900
Molecular Formula : C21H27FN3O9P
Molecular Weight : 515.43
1-((3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 19 51910
(2S,2'S)-Isopropyl 2,2'-phenoxyphosphoryl-bis-azanediyl dipropanoate
Catalogue No.:PA 19 51920
Molecular Formula : C18H29N2O6P
Molecular Weight : 400.41
Isopropyl ((((2R,3R,4R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 51930
2'-Alkene Sofosbuvir
Catalogue No.:PA 19 51940
Molecular Formula : C22H28N3O9P
Molecular Weight : 509.45
Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
Catalogue No.:PA 19 0511000
Molecular Weight : 529.46
O-Desphenyl Sofosbuvir
Catalogue No.:PA 19 0511001
Molecular Formula : C16H25FN3O9P
Molecular Weight : 453.36
Methyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 0511002
Molecular Formula : C20H25FN3O9P
Molecular Weight : 501.4
Sofosbuvir o-desisopropyl o-methyl ester
Catalogue No.:PA 19 0511007
(3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
Catalogue No.:PA 19 0511003
(3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
Catalogue No.:PA 19 0511004
(3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
Catalogue No.:PA 19 0511005
(3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
Catalogue No.:PA 19 0511006
Molecular Formula : C6H10O5
Molecular Weight : 162.14
Isopropyl ((S)-(((2R,3R,4S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 0511009
Molecular Formula : C22H30N3O10P
Molecular Weight : 527.47
((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl)methyl benzoate
Catalogue No.:PA 19 0511010
(2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-chloro-4-methyltetrahydrofuran-3-yl benzoate
Catalogue No.:PA 19 0511011
Molecular Formula : C31H26ClN3O7
Molecular Weight : 588.01
((2R,3R,4S)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
Catalogue No.:PA 19 0511013
Molecular Weight : 372.35
Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
Catalogue No.:PA 19 0511008
9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-1H-purine-2,6-dithione
Catalogue No.:PA 19 0511014
Molecular Formula : C10H12N4O4S2
Molecular Weight : 316.35
L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester
Catalogue No.:PA 19 0511015
Methyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 0511016
((2R,3R,4R)-3-(Benzoyloxy)-5-chloro-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate
Catalogue No.:PA 19 0511017
Isopropyl ((((3S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
Catalogue No.:PA 19 0511018
Isopropyl ((S)-(((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 0511019
Molecular Formula : C22H30FN4O8P
Molecular Weight : 528.47
Isopropyl ((S)-((S)-1-((2S,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)ethoxy)(phenoxy)phosphoryl)-L-alaninate
Catalogue No.:PA 19 0511020
Molecular Formula : C23H32N3O10P
Molecular Weight : 541.49
(2'S)-2'-Deoxy-2'-fluoro-2'-methyluridine
Catalogue No.:PA 19 0511021
Ethyl 2-(triphenylphosphoranylidene)propanoate
Catalogue No.:PA 19 0511022
Molecular Formula : C23H23O2P
Molecular Weight : 362.41
Chloro (R)-Phosphoryl Sofosbuvir
Catalogue No.:PA 19 0511023
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