sinomenine and its Impurities

Sinomenine is used in herbal medicine in these countries for rheumatism and arthritis. Sinomenine or cocculine is an alkaloid found in the root of the climbing plant Sinomenium acutum which is native to Japan and China. Reference standards of Sinomenine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.