Simeticone is used to relieve the symptoms of excessive gas in the gastrointestinal tract, namely bloating, burping and flatulence. It is an orally administered antifoaming agent. Reference standards of Simeticone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Simeticone
Catalogue No.:PA 46 30000
CAS :
Molecular Formula : (CH3)3Si–[–O-Si(CH3)2–]n –CH3 + SiO2
Molecular Weight : NA
Octamethylcyclotetrasiloxane
Catalogue No.:PA 46 0301000
Molecular Formula : C8H24O4Si4
Molecular Weight : 296.62
1,1-Dimethylsilanediol
Catalogue No.:PA 46 30510
Molecular Formula : C2H8O2Si
Molecular Weight : 92.17
Eicosamethylcyclodecasiloxane
Catalogue No.:PA 46 30520
Molecular Formula : C20H60O10Si10
Molecular Weight : 741.54
Trimethylsilyl 5-((trimethylsilyl)amino)-2-((trimethylsilyl)oxy)benzoate
Catalogue No.:PA 46 30530
Molecular Formula : C16H31NO3Si3
Molecular Weight : 369.68
Tetracosamethyl-cyclododecasiloxane
Catalogue No.:PA 46 30540
Molecular Formula : C24H72O12Si12
Molecular Weight : 889.85
1,1,1,5,7,7,7-Heptamethyl-3,3,5-tris(trimethylsiloxy)tetrasiloxane
Catalogue No.:PA 46 30550
Molecular Formula : C16H48O6Si7
Molecular Weight : 533.15
1,1,3,3-Tetramethyldisiloxane-1,3-diol
Catalogue No.:PA 46 30560
Molecular Formula : C4H14O3Si2
Molecular Weight : 166.32
1,1,3,3,5,5-Hexamethyltrisiloxane-1,5-diol
Catalogue No.:PA 46 30570
Molecular Formula : C6H20O4Si3
Molecular Weight : 240.48
1,1,3,3,5,5,7,7-octamethyltetrasiloxane-1,7-diol
Catalogue No.:PA 46 30580
Molecular Formula : C8H26O5Si4
Molecular Weight : 314.63
1,3,3,3-Tetramethyldisiloxanyl tris(trimethylsilyl) Silicate
Catalogue No.:PA 46 30590
Molecular Formula : C13H40O5Si6
Molecular Weight : 444.97
Heptamethyltrisiloxane
Catalogue No.:PA 46 0301001
Molecular Formula : C7H22O2Si3
Molecular Weight : 222.51
Hexadecamethylheptasiloxane
Catalogue No.:PA 46 0301002
Hydroxy-dimethyl-trimethylsilyloxysilane
Catalogue No.:PA 46 0301003
Molecular Formula : C5H16O2Si2
Molecular Weight : 164.35
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