rosiglitazone maleate and its Impurities

An oral antidiabetic agent that belongs to thiazolidinedione class of drug, used in the treatment of type 2 diabetes mellitus. Rosiglitazone is an insulin sensitizer and works by binding to the PPAR in fat cells, making the cells more responsive to insulin. Also shows anti-inflammatory effect.Reference standards of Rosiglitazone Maleate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.