Ripasudil Dihydrochloride and its Impurities

Ripasudil Dihydrochloride sold under the brand name Glanatec. it is a rho kinase inhibitor indicated to treat ocular hypertension and open-angle glaucoma. Reference standards of Ripasudil Dihydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.