Riociguat-impurities | Pharmaffiliates

riociguat and its Impurities

Riociguat belongs to the class of soluble guanylate cyclase (sGC) medication, and is used to treat pulmonary hypertension . Reference standards of Riociguat API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 46 results for riociguat Impurities
PA 18 43000

Riociguat

Riociguat

  • Catalogue No.:PA 18 43000

  • CAS :

    625115-55-1

  • Molecular Formula : C20H19FN8O2

  • Molecular Weight : 422.42

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PA 18 43510

Riociguat - Impurity B

Methyl [4,6-diamino-2-[1-benzyl-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]methylcarbamate

  • Catalogue No.:PA 18 43510

  • CAS :

    3052969-92-0

  • Molecular Formula : C20H20N8O2

  • Molecular Weight : 404.43

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PA 18 43520

2-Desfluoro-3-fluoro-riociguat

2-Desfluoro-3-fluoro-riociguat

  • Catalogue No.:PA 18 43520

  • CAS :

    NA

  • Molecular Formula : C20H19FN8O2

  • Molecular Weight : 422.16

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PA 18 43530

2-Desfluoro-4-fluoro-riociguat

2-Desfluoro-4-fluoro-riociguat

  • Catalogue No.:PA 18 43530

  • CAS :

    NA

  • Molecular Formula : C20H19FN8O2

  • Molecular Weight : 422.42

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PA 18 43540

6-Amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one

6-Amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one

  • Catalogue No.:PA 18 43540

  • CAS :

    1361569-10-9

  • Molecular Formula : C18H13FN8O

  • Molecular Weight : 376.35

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PA 18 43550

1-(4-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride

1-(4-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride

  • Catalogue No.:PA 18 43550

  • CAS :

    2512205-26-2

  • Molecular Formula : C14H13ClFN5

  • Molecular Weight : 305.74

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PA 18 43560

1-(3-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-Carboximidamide Hydrochloride

1-(3-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-Carboximidamide Hydrochloride

  • Catalogue No.:PA 18 43560

  • CAS :

    NA

  • Molecular Formula : C14H13ClFN5

  • Molecular Weight : 305.74

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PA 18 43570

Ethyl 5-Amino-1-(2-fluorobenzyl)-1H-pyrazole-3-carboxylate

Ethyl 5-Amino-1-(2-fluorobenzyl)-1H-pyrazole-3-carboxylate

  • Catalogue No.:PA 18 43570

  • CAS :

    256504-39-9

  • Molecular Formula : C13H14FN3O2

  • Molecular Weight : 263.27

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PA 18 43580

Methyl 1-[(2-Fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carboximidate

Methyl 1-[(2-Fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carboximidate

  • Catalogue No.:PA 18 43580

  • CAS :

    304874-06-4

  • Molecular Formula : C15H13FN4O

  • Molecular Weight : 284.29

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PA 18 43590

1,1'-bis(3-Fluorobenzyl)-1H,1'H-[5,6'-Bipyrazolo[3,4-b]pyridine]-3,3'-Bis(carboximidamide) Dihydrochloride

1,1'-bis(3-Fluorobenzyl)-1H,1'H-[5,6'-Bipyrazolo[3,4-b]pyridine]-3,3'-Bis(carboximidamide) Dihydrochloride

  • Catalogue No.:PA 18 43590

  • CAS :

    NA

  • Molecular Formula : C28H24Cl2F2N10

  • Molecular Weight : 609.46

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PA 18 43600

6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7-methyl-7H-purin-8(9H)-one

6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7-methyl-7H-purin-8(9H)-one

  • Catalogue No.:PA 18 43600

  • CAS :

    1361569-18-7

  • Molecular Formula : C19H15FN8O

  • Molecular Weight : 390.37

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PA 18 43610

1-[(3-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

1-[(3-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

  • Catalogue No.:PA 18 43610

  • CAS :

    2101651-50-5

  • Molecular Formula : C14H12FN5

  • Molecular Weight : 269.28

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PA 18 43620

1-(4-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

1-(4-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

  • Catalogue No.:PA 18 43620

  • CAS :

    2512205-25-1

  • Molecular Formula : C14H12FN5

  • Molecular Weight : 269.28

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PA 18 43630

1-Benzyl-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

1-Benzyl-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

  • Catalogue No.:PA 18 43630

  • CAS :

    NA

  • Molecular Formula : C14H13N5

  • Molecular Weight : 251.29

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PA 18 43640

2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine

2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine

  • Catalogue No.:PA 18 43640

  • CAS :

    428854-24-4

  • Molecular Formula : C17H15FN8

  • Molecular Weight : 350.35

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PA 18 43010

Riociguat - Impurity A

Methyl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate

  • Catalogue No.:PA 18 43010

  • CAS :

    625115-52-8

  • Molecular Formula : C19H17FN8O2

  • Molecular Weight : 408.4

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PA 18 43030

Riociguat - Impurity C

Methyl [4-amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-6-(methylamino)pyrimidin-5-yl]methylcarbamate

  • Catalogue No.:PA 18 43030

  • CAS :

    2920299-23-4

  • Molecular Formula : C21H21FN8O2

  • Molecular Weight : 436.45

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PA 18 43650

6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dimethyl-7,9-dihydro-8H-purin-8-one

6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dimethyl-7,9-dihydro-8H-purin-8-one

  • Catalogue No.:PA 18 43650

  • CAS :

    1361569-23-4

  • Molecular Formula : C20H17FN8O

  • Molecular Weight : 404.41

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PA 18 0431000

2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(phenyldiazenyl)pyrimidine-4,6-diamine

2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(phenyldiazenyl)pyrimidine-4,6-diamine

  • Catalogue No.:PA 18 0431000

  • CAS :

    428854-23-3

  • Molecular Formula : C23H18FN9

  • Molecular Weight : 439.46

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PA 18 0430040

Riociguat - Impurity D

Propan-2-yl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]methylcarbamate

  • Catalogue No.:PA 18 0430040

  • CAS :

    625115-54-0

  • Molecular Formula : C22H23FN8O2

  • Molecular Weight : 450.48

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PA STI 088842

Riociguat-d6

Riociguat-d6

  • Catalogue No.:PA STI 088842

  • CAS :

    1304478-43-0

  • Molecular Formula : C20H13D6FN8O2

  • Molecular Weight : 428.46

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PA 18 0431001

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

  • Catalogue No.:PA 18 0431001

  • CAS :

    256376-65-5

  • Molecular Formula : C14H9FN4

  • Molecular Weight : 252.25

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PA 18 0431002

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

  • Catalogue No.:PA 18 0431002

  • CAS :

    256376-68-8

  • Molecular Formula : C14H12FN5

  • Molecular Weight : 269.28

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PA 18 0431003

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride

  • Catalogue No.:PA 18 0431003

  • CAS :

    256499-19-1

  • Molecular Formula : C14H13ClFN5

  • Molecular Weight : 305.74

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PA 18 0431004

Dimethyl (6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5-diyl)dicarbamate

Dimethyl (6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5-diyl)dicarbamate

  • Catalogue No.:PA 18 0431004

  • CAS :

    2708578-77-0

  • Molecular Formula : C21H19FN8O4

  • Molecular Weight : 466.43

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PA 18 0431005

Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)carbamate

Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)carbamate

  • Catalogue No.:PA 18 0431005

  • CAS :

    2514697-53-9

  • Molecular Formula : C20H19FN8O2

  • Molecular Weight : 422.42

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PA 18 0431006

2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-N5-methylpyrimidine-4,5,6-triamine

2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-N5-methylpyrimidine-4,5,6-triamine

  • Catalogue No.:PA 18 0431006

  • CAS :

    1702271-98-4

  • Molecular Formula : C18H17FN8

  • Molecular Weight : 364.39

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PA 18 0431007

Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-((methoxycarbonyl)amino)pyrimidin-5-yl)(methyl)carbamate

Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-((methoxycarbonyl)amino)pyrimidin-5-yl)(methyl)carbamate

  • Catalogue No.:PA 18 0431007

  • CAS :

    2518331-19-4

  • Molecular Formula : C22H21FN8O4

  • Molecular Weight : 480.46

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PA 18 0431008

Lithium 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7-methyl-8-oxo-7,8-dihydropurin-9-ide

Lithium 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7-methyl-8-oxo-7,8-dihydropurin-9-ide

  • Catalogue No.:PA 18 0431008

  • CAS :

    NA

  • Molecular Formula : C19H14FLiN8O

  • Molecular Weight : 396.31

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PA STI 089135

Riociguat-13C-D3

Riociguat-13C-D3

  • Catalogue No.:PA STI 089135

  • CAS :

    2749393-44-8

  • Molecular Formula : C1913CH16D3FN8O2

  • Molecular Weight : 426.44

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PA 18 0431009

2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(2-phenylhydrazinyl)pyrimidine-4,6-diamine

2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(2-phenylhydrazinyl)pyrimidine-4,6-diamine

  • Catalogue No.:PA 18 0431009

  • CAS :

    NA

  • Molecular Formula : C23H20FN9

  • Molecular Weight : 441.47

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PA 18 0431010

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid

  • Catalogue No.:PA 18 0431010

  • CAS :

    956011-26-0

  • Molecular Formula : C14H10FN3O2

  • Molecular Weight : 271.25

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PA 18 0431011

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester

  • Catalogue No.:PA 18 0431011

  • CAS :

    256376-59-7

  • Molecular Formula : C16H14FN3O2

  • Molecular Weight : 299.31

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PA 18 0431012

1-(2-Fluorobenzyl)-N-((1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)(imino)methyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

1-(2-Fluorobenzyl)-N-((1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)(imino)methyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

  • Catalogue No.:PA 18 0431012

  • CAS :

    NA

  • Molecular Formula : C28H21F2N9

  • Molecular Weight : 521.54

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PA 18 0431013

(E)-N-(Amino(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)methylene)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

(E)-N-(Amino(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)methylene)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide

  • Catalogue No.:PA 18 0431013

  • CAS :

    NA

  • Molecular Formula : C28H21F2N9

  • Molecular Weight : 521.54

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PA 18 0431014

3-(4,6-Diamino-5-((methoxycarbonyl)(methyl)amino)pyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine 7-oxide

3-(4,6-Diamino-5-((methoxycarbonyl)(methyl)amino)pyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine 7-oxide

  • Catalogue No.:PA 18 0431014

  • CAS :

    NA

  • Molecular Formula : C20H19FN8O3

  • Molecular Weight : 438.42

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PA 18 0431015

N'-(4,6-Diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)-N,N-dimethylformimidamide

N'-(4,6-Diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)-N,N-dimethylformimidamide

  • Catalogue No.:PA 18 0431015

  • CAS :

    NA

  • Molecular Formula : C20H20FN9

  • Molecular Weight : 405.44

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PA 18 0431016

N-(4,6-Diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)-N-methylnitrous Amide

N-(4,6-Diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)-N-methylnitrous Amide

  • Catalogue No.:PA 18 0431016

  • CAS :

    NA

  • Molecular Formula : C18H16FN9O

  • Molecular Weight : 393.39

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PA 18 0431017

Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methyl(nitroso)amino)pyrimidin-5-yl)(methyl)carbamate

Methyl (4-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methyl(nitroso)amino)pyrimidin-5-yl)(methyl)carbamate

  • Catalogue No.:PA 18 0431017

  • CAS :

    NA

  • Molecular Formula : C21H20FN9O3

  • Molecular Weight : 465.45

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PA 18 0431018

Ethyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate

Ethyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate

  • Catalogue No.:PA 18 0431018

  • CAS :

    625115-49-3

  • Molecular Formula : C20H19FN8O2

  • Molecular Weight : 422.42

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PA 18 0431019

Methyl (4,6-diamino-2-(1-benzyl-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate

Methyl (4,6-diamino-2-(1-benzyl-5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate

  • Catalogue No.:PA 18 0431019

  • CAS :

    3052969-91-9

  • Molecular Formula : C19H17FN8O2

  • Molecular Weight : 408.4

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PA 18 0431020

Methyl (4,6-diamino-2-(1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate

Methyl (4,6-diamino-2-(1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate

  • Catalogue No.:PA 18 0431020

  • CAS :

    2298383-24-9

  • Molecular Formula : C13H14N8O2

  • Molecular Weight : 314.31

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PA 18 0431021

Methyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(ethyl)carbamate

Methyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(ethyl)carbamate

  • Catalogue No.:PA 18 0431021

  • CAS :

    1361570-27-5

  • Molecular Formula : C21H21FN8O2

  • Molecular Weight : 436.45

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PA 18 0431022

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

  • Catalogue No.:PA 18 0431022

  • CAS :

    256376-62-2

  • Molecular Formula : C14H11FN4O

  • Molecular Weight : 270.27

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PA 18 0431023

N-Nitroso N-Desmethyl Riociguat

N-Nitroso N-Desmethyl Riociguat

  • Catalogue No.:PA 18 0431023

  • CAS :

    NA

  • Molecular Formula : C19H16FN9O3

  • Molecular Weight : 437.4

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PA STI 089759

Riociguat-13C,D6

Riociguat-13C,D6

  • Catalogue No.:PA STI 089759

  • CAS :

    NA

  • Molecular Formula : C1913CH13D6FN8O2

  • Molecular Weight : 429.45

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