Rigosertib Sodium and its Impurities

Rigosertib Sodium (ON-01910 sodium salt, with Estybon as trade name) is a synthetic benzyl styryl sulfone in development by Onconova Therapeutics. it has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others. Reference standards of Rigosertib Sodium API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.