Rapamycin is also known as Sirolimus which is a naturally occurring triene macrolide antibiotic , used to prevent organ transplant rejection and for the treatment of lymphangioleiomyomatosis (LAM). Rapamycin was also initially used as anti fungal agent. It works by inhibiting the activation of T cells and B cells by reducing the production of interleukin-2.Reference standards of Rapamycin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Rapamycin
Catalogue No.:PA 18 26000
CAS :
Molecular Formula : C51H79NO13
Molecular Weight : 914.17
Rapamycin Dialdehyde
Catalogue No.:PA 18 26510
Molecular Formula : C51H79NO15
Molecular Weight : 946.17
27-O-Desmethyl Rapamycin
Catalogue No.:PA 18 26530
Molecular Formula : C50H77NO13
Molecular Weight : 900.17
41-O-Demethylrapamycin
Catalogue No.:PA 18 26540
Molecular Weight : 900.15
Seco Rapamycin
Catalogue No.:PA 18 26550
Prolyl-rapamycin
Catalogue No.:PA 18 26560
12-Desmethyl Rapamycin
Catalogue No.:PA 18 26570
29-Desmethyl-rapamycin
Catalogue No.:PA 18 26580
44-Ene-rapamycin
Catalogue No.:PA 18 26590
Molecular Formula : C51H77NO13
Molecular Weight : 912.16
28-epi-Rapamycin
Catalogue No.:PA 18 26600
29-Desmethoxy-rapamycin
Catalogue No.:PA 18 26610
Molecular Formula : C50H77NO12
Molecular Weight : 884.15
12-Ethyl Rapamycin
Catalogue No.:PA 18 26620
Molecular Formula : C52H81NO13
Molecular Weight : 928.2
33-Ethyl Rapamycin
Catalogue No.:PA 18 26630
42-O-tert-Butyldimethylsilyloxyethyl-d4 Rapamycin
Catalogue No.:PA STI 016250
Molecular Formula : C59H93D4NO14Si
Molecular Weight : 1076.51
(19E/Z)-seco-[4-O-[2-Hydroxy(ethyl)-d4]] Rapamycin Sodium Salt
Catalogue No.:PA STI 047640
Molecular Formula : C53H78D4NNaO14
Molecular Weight : 984.23
Demethoxy Rapamycin
Catalogue No.:PA 18 26640
Molecular Weight : 914.19
7-O-Demethyl Rapamycin
Catalogue No.:PA 18 26650
Molecular Weight : 900.16
Sirolimus Isomer A
Catalogue No.:PA 18 26660
Secorapamycin
Catalogue No.:PA 18 0261000
Molecular Formula : C51H78NNaO13
Molecular Weight : 936.17
7-O-Demethyl-7-O-ethyl-Rapamycin
Catalogue No.:PA 18 0261001
Molecular Weight : 928.21
42-O-[2-[[Hydroxy[2-(trimethylammonio)ethoxy]phosphinyl]oxy]ethyl] Rapamycin Inner Salt
Catalogue No.:PA 18 0261002
Molecular Formula : C58H95N2O17P
Molecular Weight : 1123.37
Sirolimus Isomer C
Catalogue No.:PA 18 0261003
32-O-Demethyl-rapamycin
Catalogue No.:PA 18 0261004
GSK 2126458
Catalogue No.:PA 18 0261005
Molecular Formula : C25H17F2N5O3S
Molecular Weight : 505.5
Torin 2
Catalogue No.:PA 18 0261006
Molecular Formula : C24H15F3N4O
Molecular Weight : 432.41
3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Catalogue No.:PA 18 0261007
Molecular Formula : C15H15N7O
Molecular Weight : 309.33
21-Norrapamycin
Catalogue No.:PA 18 0261008
Sirolimus 13C D3
Catalogue No.:PA STI 089156
Molecular Formula : C5013CH76D3NO13
Molecular Weight : 918.2
Rapamycin, 36-demethyl-36-ethyl
Catalogue No.:PA 18 0261010
42-Oxorapamycin
Catalogue No.:PA 18 0261009
Molecular Weight : 912.17
Secorapamycin B
Catalogue No.:PA 18 0261011
Molecular Formula : C51H81NO14
Molecular Weight : 932.2
(9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13S,14R,15E)-14-hydroxy-2,13-dimethoxy-3,9,11,15-tetramethyl-12,17-dioxooctadeca-3,5,7,15-tetraen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione
Catalogue No.:PA 18 0261012
Molecular Formula : C38H57NO11
Molecular Weight : 703.87
Sirolimus-31,42-Diester Impurity
Catalogue No.:PA 18 0261013
Molecular Formula : C61H95NO19
Molecular Weight : 1146.42
(7R)-Rapamycin
Catalogue No.:PA 18 0261014
(3R,9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione
Catalogue No.:PA 18 0261015
(9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E)-14-hydroxy-2,13-dimethoxy-3,9,11,15-tetramethyl-12,17-dioxooctadeca-3,5,7,15-tetraen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione
Catalogue No.:PA 18 0261016
Catalogue No.:PA BSC 02618591
23-Propyl Sirolimus
Catalogue No.:PA 18 0261017
Molecular Formula : C53H83NO13
Molecular Weight : 942.24
11-Propyl Sirolimus
Catalogue No.:PA 18 0261018
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