protamine sulfate and its Impurities

Protamine Sulfate is specifically used in heparin overdose, in low molecular weight heparin overdose, and to reverse the effects of heparin during delivery and heart surgery. It is now mainly made using recombinant biotechnology. Reference standards of Protamine Sulfate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.