Proguanil is used in combination with chloroquine. Proguanil is a rodrug of its active metabolite cycloguanil, which is an inhibitor of dihydrofolate reductase (DHFR). It is also known as chlorguanide and chloroguanide.Reference standards of Proguanil API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Proguanil
Catalogue No.:PA 43 84000
CAS :
Molecular Formula : C11H16ClN5
Molecular Weight : 253.73
4-Chlorophenylbiguanide
Catalogue No.:PA 43 28510
Molecular Formula : C8H10ClN5
Molecular Weight : 211.65
Catalogue No.:PA IPIPRS 12 10
Molecular Formula :
Molecular Weight : NA
Proguanil hydrochloride - reference spectrum (Y0000179)
Catalogue No.:PA EPY0000179
Molecular Formula : NA
Proguanil impurity C (Y0000181)
Catalogue No.:PA EPY0000181
Proguanil impurity D (Y0000182)
Catalogue No.:PA EPY0000182
Proguanil for system suitability (Y0001885)
Catalogue No.:PA EPY0001885
Proguanil Related Compound A (1-cyano-3-isopropylguanidine) (1568028)
Catalogue No.:PA USP1568028
Proguanil Hydrochloride (1568040)
Catalogue No.:PA USP1568040
Proguanil Related Compound C (1,5-bis(4-chlorophenyl)biguanide hydrochloride) (1568051)
Catalogue No.:PA USP1568051
Proguanil Related Compound D (1,5-bis(1-methylethyl)biguanide hydrochloride) (1568062)
Catalogue No.:PA USP1568062
Proguanil Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine) (1568073)
Catalogue No.:PA USP1568073
Proguanil Related Compound F (1-(3,4-dichlorophenyl)-5-isopropylbiguanide hydrochloride) (1568084)
Catalogue No.:PA USP1568084
Proguanil Related Compound G (1-(3-chlorophenyl)-5-isopropylbiguanide hydrochloride) (1568095)
Catalogue No.:PA USP1568095
proguanil hydrochloride (297RB)
Catalogue No.:PA BP297RB
Proguanil Nitroso Impurity 2
Catalogue No.:PA 43 0841000
Molecular Formula : C11H15ClN6O
Molecular Weight : 282.73
Proguanil Nitroso Impurity 3
Catalogue No.:PA 43 0841001
Proguanil Nitroso Impurity 1
Catalogue No.:PA 43 0841002
Molecular Formula : C11H14ClN7O2
Molecular Weight : 311.73
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