Pexidartinib and its Impurities

Pexidartinib, sold under the brand name Turalio. It is an antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. Reference standards of Pexidartinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.