Pemetrexed is used to treat certain types of cancer. Pemetrexed is a chemotherapy drug manufactured and marketed by Eli Lilly and Company.Reference standards of Pemetrexed API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(2S)-2-[[4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]amino]pentanedioic Acid
Catalogue No.:PA 16 09010
CAS :
Molecular Formula : C21H23N5O6
Molecular Weight : 441.44
(2S,2′S)-2,2′-[[(5R)-2,2′-Diamino-4,4′,6-trioxo-1,4,4′,6,7,7′-hexahydro-1′H,5H-5,6′-bipyrrolo[2,3-d]pyrimidine-5,5′-diyl]bis(ethylenebenzene-4,1-diylcarbonylimino)]dipentanedioic Acid
Catalogue No.:PA 16 09020
Molecular Formula : C40H40N10O13
Molecular Weight : 868.82
(2S,2'S)-2,2'-[[(5S)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethylenebenzene-4,1-diylcarbonylimino)]dipentanedioic Acid
Catalogue No.:PA 16 09030
Molecular Weight : 868.8
(2R)-2-[[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]amino]pentanedioic Acid Disodium Salt
Catalogue No.:PA 16 09050
Molecular Formula : C20H19N5Na2O6
Molecular Weight : 471.37
4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid
Catalogue No.:PA 16 09510
Molecular Formula : C15H14N4O3
Molecular Weight : 298.3
Pemetrexed 6-Oxo Diacid Impurity
Catalogue No.:PA 16 09590
Molecular Formula : C20H21N5O7
Molecular Weight : 443.41
Mixture of Pemetrexed Acid Impurity B and Impurity C
Catalogue No.:PA 16 0091005
(4-{2-[(RS)-2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-3H -pyrrolo[2,3-d]pyrimidin-5-yl]ethyl}benzoyl)-l-glutamic acid
Catalogue No.:PA 16 0091013
Molecular Weight : 443.42
Pemetrexed
Catalogue No.:PA 16 09000
Molecular Formula : C20H21N5O6
Molecular Weight : 427.41
(2S)-2-[[4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]amino]pentanedioic Acid Disodium Salt
Catalogue No.:PA 16 09011
Molecular Formula : C21H21N5Na2O6
Molecular Weight : 485.4
(2S)-2-[[(4S)-4-[[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-4-carboxybutanoyl]amino]pentanedioic Acid
Catalogue No.:PA 16 09040
Molecular Formula : C25H28N6O9
Molecular Weight : 556.52
(2S)-2-[[(4S)-4-[[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]amino]-4-carboxybutanoyl]amino]pentanedioic Acid Trisodium Salt
Catalogue No.:PA 16 09041
Molecular Formula : C25H25N6Na3O9
Molecular Weight : 622.47
(2R)-2-[[4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]amino]pentanedioic Acid
Catalogue No.:PA 16 09051
Pemetrexed Dimethyl Ester
Catalogue No.:PA 16 09520
Molecular Formula : C22H25N5O6
Molecular Weight : 455.46
Pemetrexed Dipotassium Acid
Catalogue No.:PA 16 09530
Molecular Formula : C20H19K2N5O6
Molecular Weight : 503.59
{4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-4-L-glutamyl-L-glutamic Acid
Catalogue No.:PA 16 09540
Molecular Formula : C26H30N6O9
Molecular Weight : 570.55
Pemetrexed-1-methyl Ester Sodium
Catalogue No.:PA 16 09550
Molecular Formula : C21H22N5NaO6
Molecular Weight : 463.42
Pemetrexed-1-methyl Ester
Catalogue No.:PA 16 09560
Sodium (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoate
Catalogue No.:PA 16 09570
4-(4-Oxobutyl)benzoic Acid Methyl Ester
Catalogue No.:PA 16 09580
Molecular Formula : C12H14O3
Molecular Weight : 206.24
Sodium (4R)-4-{[4-(2-{2-Amino-4-oxo-1H,4H,7H- pyrrolo[2,3-d]pyrimidin-5- yl}ethyl)phenyl]formamido}-5-methoxy-5- oxopentanoate
Catalogue No.:PA 16 09600
N-Methyl Pemetrexed-d3
Catalogue No.:PA STI 088075
Molecular Formula : C21H20D3N5O6
Molecular Weight : 444.46
Pemetrexed-d5 Disodium Salt
Catalogue No.:PA STI 088076
Molecular Formula : C20H14D5N5Na2O6
Molecular Weight : 476.41
Pemetrexed-d5 Diethyl Ester
Catalogue No.:PA STI 088077
Molecular Formula : C24H24D5N5O6
Molecular Weight : 488.55
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Diethyl Ester 4-Methylbenzenesulfonate
Catalogue No.:PAI 16 014010
Molecular Formula : C31H37N5O9S
Molecular Weight : 655.72
(S)-Diethyl 2-(4-(2-(2-amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate
Catalogue No.:PAI 16 014020
Molecular Formula : C25H31N5O6
Molecular Weight : 497.54
(S)-2-(4-(2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-(((S)-1,5-diethoxy-1,5-dioxopentan-2-yl)amino)-5-oxopentanoic Acid
Catalogue No.:PAI 16 014030
Molecular Formula : C30H38N6O9
Molecular Weight : 626.66
(S)-2-((S)-4-(4-(2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-4-carboxybutanamido)pentanedioic Acid
Catalogue No.:PAI 16 014040
(S)-Diethyl 2-((S)-4-(((benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanamido)pentanedioate
Catalogue No.:PAI 16 014050
Molecular Formula : C23H32N2O9
Molecular Weight : 480.51
(S)-Diethyl 2-((S)-4-amino-5-methoxy-5-oxopentanamido)pentanedioate
Catalogue No.:PAI 16 014060
Molecular Formula : C15H26N2O7
Molecular Weight : 346.38
(S)-4-(((Benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanoic Acid
Catalogue No.:PAI 16 014070
Molecular Formula : C14H17NO6
Molecular Weight : 295.29
5-Methyl N-Carbobenzoxy-L-glutaMate
Catalogue No.:PAI 16 014080
(S)-Diethyl 2-((S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanamido)pentanedioate
Catalogue No.:PAI 16 014090
(S)-Diethyl 2-((S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanamido)pentanedioate 4-methylbenzenesulfonate
Catalogue No.:PAI 16 014100
Molecular Formula : C37H46N6O12S
Molecular Weight : 798.86
(S)-Diethyl 2-((S)-4-(4-(2-(2-amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanamido)pentanedioate
Catalogue No.:PAI 16 014110
Molecular Formula : C31H40N6O9
Molecular Weight : 640.68
Di lithium (4-(2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate
Catalogue No.:PA 16 09610
Molecular Formula : C20H19Li2N5O7
Molecular Weight : 455.28
(4-(2-(2-Amino-6-hydroxy-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic Acid
Catalogue No.:PA 16 09620
(4-(2-(2,2'-Diamino-5-(4-((1-carboxy-4-(2-carboxyethoxy)-4-oxobutyl)carbamoyl)phenethyl)-6-hydroxy-4,4'-dioxo-4,4',5,6,7,7'-hexahydro-3H,3'H-[5,6'-bipyrrolo[2,3-d]pyrimidin]-5'-yl)ethyl)benzoyl)glutamic Acid
Catalogue No.:PA 16 09630
Molecular Formula : C43H46N10O15
Molecular Weight : 942.9
Pemetrexed impurity mixture (Y0001535)
Catalogue No.:PA EPY0001535
Molecular Formula : NA
Molecular Weight : NA
Pemetrexed for system suitability (Y0001538)
Catalogue No.:PA EPY0001538
Pemetrexed disodium heptahydrate (Y0001539)
Catalogue No.:PA EPY0001539
Catalogue No.:PAI 16 014120
Molecular Formula : C20H20N5NaO6
Molecular Weight : 449.40
4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Methyl Ester
Catalogue No.:PA 16 09640
Molecular Formula : C16H16N4O3
Molecular Weight : 312.32
Pemetrexed-d5
Catalogue No.:PA STI 088078
Molecular Formula : C20H16D5N5O6
Molecular Weight : 432.45
4-(3-Bromo-4-oxobutyl)benzoic Acid Methyl Ester
Catalogue No.:PA 16 09680
Molecular Formula : C12H13BrO3
Molecular Weight : 285.14
Pemetrexed Hydroxy lactam
Catalogue No.:PA 16 0091000
Molecular Formula : C20H21N5O8
Molecular Weight : 459.42
Mixture of Pemetrexed Impurity A and Impurity D
Catalogue No.:PA 16 0091001
N-2-[(Dimethylamino)methylene]amino Pemetrexed
Catalogue No.:PA 16 0091002
Molecular Formula : C23H26N6O6
Molecular Weight : 482.5
Pemetrexed L-Glutamyl-L-glutamic Acid
Catalogue No.:PA 16 0091003
Molecular Weight : 556.53
Methyl 4-(2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate
Catalogue No.:PA 16 0091004
Molecular Formula : C16H16N4O4
Molecular Weight : 328.33
4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid
Catalogue No.:PA 16 0091007
Molecular Formula : C15H14N4O4
Molecular Weight : 314.3
(S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid
Catalogue No.:PA 16 0091008
(4-(3-(2,6-Diamino-4-oxo-1,4-dihydropyrimidin-5-yl)-3-oxopropyl)benzoyl)-L-glutamic acid
Catalogue No.:PA 16 0091009
Molecular Formula : C19H21N5O7
Molecular Weight : 431.41
4-[2'-(7"-Deazaguanine)ethyl]benzoic Acid N-hydroxysuccinimide ester
Catalogue No.:PA 16 0091010
Molecular Formula : C19H17N5O5
Molecular Weight : 395.38
N2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-N5-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-L-glutamine
Catalogue No.:PA 16 0091011
Molecular Formula : C24H30N6O8
Molecular Weight : 530.54
4-(4-Hydroxybutyl)benzoic Acid
Catalogue No.:PA 16 0091014
Molecular Formula : C11H14O3
Molecular Weight : 194.23
Diethyl (4-(2-(2-(((dimethylamino)methylene)amino)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate
Catalogue No.:PA 16 0091015
Molecular Formula : C27H34N6O6
Molecular Weight : 538.61
Methyl 4-(4-hydroxybut-1-en-1-yl)benzoate
Catalogue No.:PA 16 0091016
(4-(3-(2-Amino-4-formamido-6-oxo-1,6-dihydropyrimidin-5-yl)-3-oxopropyl)benzoyl)-L-glutamic Acid
Catalogue No.:PA 16 0091017
4-(4-Oxobutyl)benzoic Acid
Catalogue No.:PA 16 0091018
Molecular Formula : C11H12O3
Molecular Weight : 192.21
Dimethyl (4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate 4-methylbenzenesulfonate
Catalogue No.:PA 16 0091019
Molecular Formula : C29H33N5O9S
Molecular Weight : 627.67
4,6-Dimethoxy-1,3,5-triazin-2-yl 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate
Catalogue No.:PA 16 0091020
Molecular Formula : C20H19N7O5
Molecular Weight : 437.42
Methyl (E)-4-(4-hydroxybut-1-en-1-yl)benzoate
Catalogue No.:PA 16 0091021
Methyl 4-(4-oxobut-1-en-1-yl)benzoate
Catalogue No.:PA 16 0091022
Molecular Formula : C12H12O3
Molecular Weight : 204.23
Methyl 4-(3-bromo-4-oxobut-1-en-1-yl)benzoate
Catalogue No.:PA 16 0091023
Molecular Formula : C12H11BrO3
Molecular Weight : 283.12
Methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)vinyl)benzoate
Catalogue No.:PA 16 0091024
Molecular Formula : C16H14N4O3
Molecular Weight : 310.31
4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)vinyl)benzoic Acid
Catalogue No.:PA 16 0091025
Molecular Formula : C15H12N4O3
Molecular Weight : 296.29
Methyl (S)-1-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-5-oxopyrrolidine-2-carboxylate
Catalogue No.:PA 16 0091026
Molecular Formula : C21H21N5O5
Molecular Weight : 423.43
(S)-1-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-5-oxopyrrolidine-2-carboxylic acid
Catalogue No.:PA 16 0091027
Molecular Formula : C20H19N5O5
Molecular Weight : 409.4
Methyl 4-(4-hydroxybutyl)benzoate
Catalogue No.:PA 16 0091028
Molecular Formula : C12H16O3
Molecular Weight : 208.26
Methyl 4-(4-oxobutan-2-yl)benzoate
Catalogue No.:PA 16 0091029
Dimethyl ((S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoyl)-L-glutamate
Catalogue No.:PA 16 0091030
Molecular Formula : C28H34N6O9
Molecular Weight : 598.61
Dimethyl ((S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoyl)-L-glutamate
Catalogue No.:PA 16 0091031
4-(2-(2-Hydroxy-4-oxo-4,4a,7,7a-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic Acid
Catalogue No.:PA 16 0091032
Molecular Formula : C15H15N3O4
Molecular Weight : 301.3
(4-(2-(2-Hydroxy-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic Acid
Catalogue No.:PA 16 0091033
Molecular Formula : C20H20N4O7
Molecular Weight : 428.4
(4-(2-(2-Amino-5-hydroxy-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-D-glutamic Acid
Catalogue No.:PA 16 0091034
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