Olaparib is used to treat ovarian cancer in people with a specific gene who have not improved or who have worsened after treatment with at least three other therapies.Reference standards of Olaparib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Olaparib
Catalogue No.:PA 15 70000
CAS :
Molecular Formula : C24H23FN4O3
Molecular Weight : 434.47
Tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carboxylate
Catalogue No.:PA 15 0701006
Molecular Formula : C25H27FN4O4
Molecular Weight : 466.51
4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701007
Molecular Formula : C20H19FN4O2
Molecular Weight : 366.4
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
Catalogue No.:PA 15 0701019
Molecular Formula : C16H11FN2O3
Molecular Weight : 298.27
3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic Acid
Catalogue No.:PA 15 70510
Molecular Formula : C16H12N2O3
Molecular Weight : 280.28
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 70520
Molecular Formula : C24H24N4O3
Molecular Weight : 416.48
Olaparib-D4
Catalogue No.:PA STI 089003
Molecular Formula : C24H19D4FN4O3
Molecular Weight : 438.5
4-(4-Fluoro-3-(4-(4-hydroxybutanoyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701000
Molecular Formula : C24H25FN4O4
Molecular Weight : 452.49
6-Chloro-4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701001
Molecular Formula : C24H22ClFN4O3
Molecular Weight : 468.91
Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
Catalogue No.:PA 15 0701002
Molecular Formula : C10H11O5P
Molecular Weight : 242.17
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile
Catalogue No.:PA 15 0701003
Molecular Formula : C16H10FN3O
Molecular Weight : 279.27
4-Cyclopropanoylpiperazine-1-carboxylic Acid tert-Butyl Ester
Catalogue No.:PA 15 0701004
Molecular Formula : C13H22N2O3
Molecular Weight : 254.33
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzamide
Catalogue No.:PA 15 0701005
Molecular Formula : C16H12FN3O2
Molecular Weight : 297.29
4,4'-(((Piperazine-1,4-dicarbonyl)bis(4-fluoro-3,1-phenylene))bis(methylene))bis(phthalazin-1(2H)-one)
Catalogue No.:PA 15 0701008
Molecular Formula : C36H28F2N6O4
Molecular Weight : 646.65
4-(3-(4-Butyrylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701009
Molecular Formula : C24H25FN4O3
Molecular Weight : 436.49
1H-benzo[d][1,2,3]triazol-1-yl 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoate
Catalogue No.:PA 15 0701010
Molecular Formula : C22H14FN5O3
Molecular Weight : 415.38
2-Fluoro-N,N-dimethyl-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzamide
Catalogue No.:PA 15 0701011
Molecular Formula : C18H16FN3O2
Molecular Weight : 325.34
(Z)-2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzoic acid
Catalogue No.:PA 15 0701012
Molecular Formula : C16H9FO4
Molecular Weight : 284.24
(Z)-3-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzylidene)isobenzofuran-1(3H)-one
Catalogue No.:PA 15 0701013
Molecular Formula : C24H21FN2O4
Molecular Weight : 420.44
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)-1,2-dihydrophthalazin-1-yl cyclopropanecarboxylate
Catalogue No.:PA 15 0701014
Molecular Formula : C28H29FN4O4
Molecular Weight : 504.56
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzoyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701015
Molecular Formula : C24H21FN4O4
Molecular Weight : 448.45
Piperazine-1,4-diylbis(cyclopropylmethanone)
Catalogue No.:PA 15 0701016
Molecular Formula : C12H18N2O2
Molecular Weight : 222.29
2-((Dimethoxyphosphoryl)((methoxy(3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphoryl)oxy)methyl)benzoic acid
Catalogue No.:PA 15 0701017
Molecular Formula : C19H20O10P2
Molecular Weight : 470.31
Cyclopropanecarbonyl Chloride
Catalogue No.:PA 15 0701018
Molecular Formula : C4H5ClO
Molecular Weight : 104.53
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-N-(5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-1H-indazol-3-yl)benzamide
Catalogue No.:PA 15 0701020
Molecular Formula : C32H22FN7O3
Molecular Weight : 571.57
4-((3-Hydroxy-1H-indazol-5-yl)methyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701021
Molecular Formula : C16H12N4O2
Molecular Weight : 292.3
Olaparib D5
Catalogue No.:PA STI 089147
Molecular Formula : C24H18D5FN4O3
Molecular Weight : 439.5
1,2-bis(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)ethane-1,2-dione
Catalogue No.:PA 15 0701022
Molecular Formula : C42H36F2N8O6
Molecular Weight : 786.8
4-(4-Fluoro-3-(4-nitrosopiperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701023
Molecular Formula : C20H18FN5O3
Molecular Weight : 395.39
4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carbaldehyde
Catalogue No.:PA 15 0701024
Molecular Formula : C21H19FN4O3
Molecular Weight : 394.41
4-(3-(4-Acetylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701025
Molecular Formula : C22H21FN4O3
Molecular Weight : 408.43
Methyl 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoate
Catalogue No.:PA 15 0701026
Molecular Formula : C17H13FN2O3
Molecular Weight : 312.3
4-((3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorophenyl)(2-oxopyrrolidin-1-yl)methyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701027
Molecular Formula : C28H28FN5O4
Molecular Weight : 517.56
4-(5-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-2-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701028
4-(2-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701029
4-(4-Fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701030
Molecular Formula : C15H11FN2O
Molecular Weight : 254.26
4-(3-Bromo-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701031
Molecular Formula : C15H10BrFN2O
Molecular Weight : 333.16
(4-Fluoro-1,3-phenylene)bis((4-(cyclopropanecarbonyl)piperazin-1-yl)methanone)
Catalogue No.:PA 15 0701032
Molecular Formula : C24H29FN4O4
Molecular Weight : 456.52
(Z)-2-(2-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorophenyl)-1-hydrazineylvinyl)benzoic Acid
Catalogue No.:PA 15 0701033
1-(Cyclopropylmethyl)-4-nitrosopiperazine
Catalogue No.:PA 15 0701034
Molecular Formula : C8H15N3O
Molecular Weight : 169.23
1-Methanesulfonyloxy-1,2,3-benzotriazole
Catalogue No.:PA 15 0701035
Molecular Formula : C7H7N3O3S
Molecular Weight : 213.21
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-hydroxybenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701036
Molecular Formula : C24H24N4O4
Molecular Weight : 432.48
4-(3-(4-Nitrosopiperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701037
Molecular Formula : C20H19N5O3
Molecular Weight : 377.4
Phthalidyl Bromide
Catalogue No.:PA 15 0701038
Molecular Formula : C8H5BrO2
Molecular Weight : 213.03
3,3-Dibromoisobenzofuran-1(3H)-one
Catalogue No.:PA 15 0701039
Molecular Formula : C8H4Br2O2
Molecular Weight : 291.93
3,6-Dibromophthalide
Catalogue No.:PA 15 0701040
3,4,6-Tribromoisobenzofuran-1(3H)-one
Catalogue No.:PA 15 0701041
Molecular Formula : C8H3Br3O2
Molecular Weight : 370.82
3,3,6-Tribromoisobenzofuran-1(3H)-one
Catalogue No.:PA 15 0701042
3,3,4,6-Tetrabromoisobenzofuran-1(3H)-one
Catalogue No.:PA 15 0701043
Molecular Formula : C8H2Br4O2
Molecular Weight : 449.72
5,5'-(1-Hydroxy-2-oxoethane-1,2-diyl)bis(2-fluorobenzonitrile)
Catalogue No.:PA 15 0701044
Molecular Formula : C16H8F2N2O2
Molecular Weight : 298.25
6,6'-Oxybis(3-formylbenzonitrile)
Catalogue No.:PA 15 0701045
Molecular Formula : C16H8N2O3
Molecular Weight : 276.25
3,5-Dibromo-4-fluorobenzaldehyde
Catalogue No.:PA 15 0701046
Molecular Formula : C7H3Br2FO
Molecular Weight : 281.91
2-Fluoro-5-formylisophthalonitrile
Catalogue No.:PA 15 0701047
Molecular Formula : C9H3FN2O
Molecular Weight : 174.13
3-Bromo-2-fluoro-5-formylbenzonitrile
Catalogue No.:PA 15 0701048
Molecular Formula : C8H3BrFNO
Molecular Weight : 228.02
4-Formylphthalonitrile
Catalogue No.:PA 15 0701049
Molecular Formula : C9H4N2O
Molecular Weight : 156.14
2-Methylcyclopropane-1-carboxylic Acid
Catalogue No.:PA 15 0701050
Molecular Formula : C5H8O2
Molecular Weight : 100.12
4-(4-Fluoro-3-(4-isobutyrylpiperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701051
2-Fluoro-5-formylbenzonitrile
Catalogue No.:PA 15 0701052
Molecular Formula : C8H4FNO
Molecular Weight : 149.12
Dimethyl (5-bromo-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
Catalogue No.:PA 15 0701053
Molecular Formula : C10H10BrO5P
Molecular Weight : 321.06
3-Chlorophthalide
Catalogue No.:PA 15 0701054
Molecular Formula : C8H5ClO2
Molecular Weight : 168.58
Dimethyl (5-chloro-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
Catalogue No.:PA 15 0701055
Molecular Formula : C10H10ClO5P
Molecular Weight : 276.61
Cyclopropyl(4-ethylpiperazin-1-yl)methanone
Catalogue No.:PA 15 0701056
Molecular Formula : C10H18N2O
Molecular Weight : 182.27
Ethyl cyclopropanecarboxylate
Catalogue No.:PA 15 0701057
Molecular Formula : C6H10O2
Molecular Weight : 114.14
(4-(5-((4-Chlorophthalazin-1-yl)methyl)-2-fluorobenzoyl)piperazin-1-yl)(cyclopropyl)methanone
Catalogue No.:PA 15 0701058
Molecular Formula : C24H22ClFN4O2
Molecular Weight : 452.91
(4-(5-((1H-Indol-3-yl)methyl)-2-fluorobenzoyl)piperazin-1-yl)(cyclopropyl)methanone
Catalogue No.:PA 15 0701059
Molecular Formula : C24H24FN3O2
Molecular Weight : 405.47
2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzoic Acid
Catalogue No.:PA 15 0701060
4-((3-Amino-1H-indazol-5-yl)methyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701061
Molecular Formula : C16H13N5O
Molecular Weight : 291.31
(Z)-3-(3-Bromo-4-fluorobenzylidene)isobenzofuran-1(3H)-one
Catalogue No.:PA 15 0701062
Molecular Formula : C15H8BrFO2
Molecular Weight : 319.13
Dimethyl (5,7-dichloro-3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
Catalogue No.:PA 15 0701063
Molecular Formula : C10H9Cl2O5P
Molecular Weight : 311.05
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