Nirmatrelvir and its Impurities

Nirmatrelvir is an antiviral medication developed by Pfizer which acts as an orally active 3C-like protease inhibitor. It is part of the nirmatrelvir/ritonavir combination sold under the brand name Paxlovid. Reference standards of Nirmatrelvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 27 results for Nirmatrelvir Impurities
PA 14 1360000

Nirmatrelvir

Nirmatrelvir

  • Catalogue No.:PA 14 1360000

  • CAS :

    2628280-40-8

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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PA 14 1361000

(S)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

(S)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

  • Catalogue No.:PA 14 1361000

  • CAS :

    2628280-48-6

  • Molecular Formula : C7H14ClN3O2

  • Molecular Weight : 207.66

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PA 14 1361001

(1R,2S,5S)-N-((S)-1-Amino-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-N-((S)-1-Amino-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361001

  • CAS :

    2755812-81-6

  • Molecular Formula : C23H34F3N5O5

  • Molecular Weight : 517.55

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PA 14 1361002

(1R,2S,5S)-N-((R)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-N-((R)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361002

  • CAS :

    2755812-41-8

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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PA 14 1361003

(S)-2-((1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoic Acid

(S)-2-((1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoic Acid

  • Catalogue No.:PA 14 1361003

  • CAS :

    3057189-15-5

  • Molecular Formula : C23H33F3N4O6

  • Molecular Weight : 518.53

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PA 14 1361004

Methyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

Methyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

  • Catalogue No.:PA 14 1361004

  • CAS :

    2879641-46-8

  • Molecular Formula : C24H35F3N4O6

  • Molecular Weight : 532.56

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PA 14 1361005

N-((S)-1-((1R,2S,5S)-2-Cyano-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2,2,2-trifluoroacetamide

N-((S)-1-((1R,2S,5S)-2-Cyano-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2,2,2-trifluoroacetamide

  • Catalogue No.:PA 14 1361005

  • CAS :

    2801608-29-5

  • Molecular Formula : C16H22F3N3O2

  • Molecular Weight : 345.37

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PA 14 1361006

 (2S)-3-(2-chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide

(2S)-3-(2-chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide

  • Catalogue No.:PA 14 1361006

  • CAS :

    NA

  • Molecular Formula : C23H33ClF3N5O4

  • Molecular Weight : 535.99

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PA 14 1361007

Isopropyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

Isopropyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

  • Catalogue No.:PA 14 1361007

  • CAS :

    NA

  • Molecular Formula : C26H39F3N4O6

  • Molecular Weight : 560.62

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PA 14 1361008

(2S,3S)-3-(2-Chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide

(2S,3S)-3-(2-Chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide

  • Catalogue No.:PA 14 1361008

  • CAS :

    NA

  • Molecular Formula : C23H33ClF3N5O4

  • Molecular Weight : 535.99

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PA STI 089311

Nirmatrelvir-D9

Nirmatrelvir-D9

  • Catalogue No.:PA STI 089311

  • CAS :

    2861202-76-6

  • Molecular Formula : C23H23D9F3N5O4

  • Molecular Weight : 508.59

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PA 14 1361009

(R)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

(R)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

  • Catalogue No.:PA 14 1361009

  • CAS :

    2889532-79-8

  • Molecular Formula : C7H14ClN3O2

  • Molecular Weight : 207.66

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PA 14 1361010

Methyl (1R,2R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Methyl (1R,2R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

  • Catalogue No.:PA 14 1361010

  • CAS :

    1932411-98-7

  • Molecular Formula : C9H15NO2

  • Molecular Weight : 169.22

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PA 14 1361011

(1R,2S,5S)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-N-(2,2,2-trifluoroacetyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-N-(2,2,2-trifluoroacetyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361011

  • CAS :

    NA

  • Molecular Formula : C25H31F6N5O5

  • Molecular Weight : 595.54

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PA 14 1361012

(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361012

  • CAS :

    NA

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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PA 14 1361013

(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361013

  • CAS :

    NA

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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PA 14 1361014

(1R,2S,5S)-3-((S)-2-Amino-3,3-dimethylbutanoyl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-3-((S)-2-Amino-3,3-dimethylbutanoyl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361014

  • CAS :

    2883654-28-0

  • Molecular Formula : C21H33N5O3

  • Molecular Weight : 403.53

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PA 14 1361015

(1R,2S,5S)-3-((S)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

(1R,2S,5S)-3-((S)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

  • Catalogue No.:PA 14 1361015

  • CAS :

    394735-37-6

  • Molecular Formula : C19H32N2O5

  • Molecular Weight : 368.47

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PA 14 1361016

(1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

(1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

  • Catalogue No.:PA 14 1361016

  • CAS :

    2755812-45-2

  • Molecular Formula : C16H23F3N2O4

  • Molecular Weight : 364.37

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PA 14 1361017

(1R,2S,5S)-3-((R)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

(1R,2S,5S)-3-((R)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

  • Catalogue No.:PA 14 1361017

  • CAS :

    NA

  • Molecular Formula : C16H23F3N2O4

  • Molecular Weight : 364.37

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PA 14 1361018

Methyl (S)-2-amino-3-((S)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride

Methyl (S)-2-amino-3-((S)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride

  • Catalogue No.:PA 14 1361018

  • CAS :

    1429218-41-6

  • Molecular Formula : C8H15ClN2O3

  • Molecular Weight : 222.67

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PA 14 1361019

Methyl (R)-2-amino-3-((R)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride

Methyl (R)-2-amino-3-((R)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride

  • Catalogue No.:PA 14 1361019

  • CAS :

    2738028-87-8

  • Molecular Formula : C8H15ClN2O3

  • Molecular Weight : 222.67

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PA 14 1361020

(S)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

(S)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

  • Catalogue No.:PA 14 1361020

  • CAS :

    NA

  • Molecular Formula : C7H14ClN3O2

  • Molecular Weight : 207.66

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PA 14 1361021

(R)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

(R)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

  • Catalogue No.:PA 14 1361021

  • CAS :

    NA

  • Molecular Formula : C7H14ClN3O2

  • Molecular Weight : 207.66

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PA 14 1361022

(1R,2S,5S)-N-((R)-1-Cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-N-((R)-1-Cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361022

  • CAS :

    NA

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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PA 14 1361023

(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile

(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile

  • Catalogue No.:PA 14 1361023

  • CAS :

    1037559-82-2

  • Molecular Formula : C8H12N2

  • Molecular Weight : 136.2

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PA BSC 13614947

(aS,3S)-a-[(tert-Butyloxycarbonyl)amino]-2-oxo-3-pyrrolidinepropanoic Acid Methyl Ester (BSC)

(aS,3S)-a-[(tert-Butyloxycarbonyl)amino]-2-oxo-3-pyrrolidinepropanoic Acid Methyl Ester

  • Catalogue No.:PA BSC 13614947

  • CAS :

    328086-60-8

  • Molecular Formula : C13H22N2O5

  • Molecular Weight : 286.33

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