Nirmatrelvir is an antiviral medication developed by Pfizer which acts as an orally active 3C-like protease inhibitor. It is part of the nirmatrelvir/ritonavir combination sold under the brand name Paxlovid. Reference standards of Nirmatrelvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Nirmatrelvir
Catalogue No.:PA 14 1360000
CAS :
Molecular Formula : C23H32F3N5O4
Molecular Weight : 499.54
(S)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride
Catalogue No.:PA 14 1361000
Molecular Formula : C7H14ClN3O2
Molecular Weight : 207.66
(1R,2S,5S)-N-((S)-1-Amino-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
Catalogue No.:PA 14 1361001
Molecular Formula : C23H34F3N5O5
Molecular Weight : 517.55
(1R,2S,5S)-N-((R)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
Catalogue No.:PA 14 1361002
(S)-2-((1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoic Acid
Catalogue No.:PA 14 1361003
Molecular Formula : C23H33F3N4O6
Molecular Weight : 518.53
Methyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate
Catalogue No.:PA 14 1361004
Molecular Formula : C24H35F3N4O6
Molecular Weight : 532.56
N-((S)-1-((1R,2S,5S)-2-Cyano-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2,2,2-trifluoroacetamide
Catalogue No.:PA 14 1361005
Molecular Formula : C16H22F3N3O2
Molecular Weight : 345.37
(2S)-3-(2-chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide
Catalogue No.:PA 14 1361006
Molecular Formula : C23H33ClF3N5O4
Molecular Weight : 535.99
Isopropyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate
Catalogue No.:PA 14 1361007
Molecular Formula : C26H39F3N4O6
Molecular Weight : 560.62
(2S,3S)-3-(2-Chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide
Catalogue No.:PA 14 1361008
Nirmatrelvir-D9
Catalogue No.:PA STI 089311
Molecular Formula : C23H23D9F3N5O4
Molecular Weight : 508.59
(R)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride
Catalogue No.:PA 14 1361009
Methyl (1R,2R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate
Catalogue No.:PA 14 1361010
Molecular Formula : C9H15NO2
Molecular Weight : 169.22
(1R,2S,5S)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-N-(2,2,2-trifluoroacetyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide
Catalogue No.:PA 14 1361011
Molecular Formula : C25H31F6N5O5
Molecular Weight : 595.54
(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
Catalogue No.:PA 14 1361012
(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
Catalogue No.:PA 14 1361013
(1R,2S,5S)-3-((S)-2-Amino-3,3-dimethylbutanoyl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
Catalogue No.:PA 14 1361014
Molecular Formula : C21H33N5O3
Molecular Weight : 403.53
(1R,2S,5S)-3-((S)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid
Catalogue No.:PA 14 1361015
Molecular Formula : C19H32N2O5
Molecular Weight : 368.47
(1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid
Catalogue No.:PA 14 1361016
Molecular Formula : C16H23F3N2O4
Molecular Weight : 364.37
(1R,2S,5S)-3-((R)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid
Catalogue No.:PA 14 1361017
Methyl (S)-2-amino-3-((S)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride
Catalogue No.:PA 14 1361018
Molecular Formula : C8H15ClN2O3
Molecular Weight : 222.67
Methyl (R)-2-amino-3-((R)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride
Catalogue No.:PA 14 1361019
(S)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride
Catalogue No.:PA 14 1361020
(R)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride
Catalogue No.:PA 14 1361021
(1R,2S,5S)-N-((R)-1-Cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
Catalogue No.:PA 14 1361022
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile
Catalogue No.:PA 14 1361023
Molecular Formula : C8H12N2
Molecular Weight : 136.2
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