Nilotinib is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Nilotinib
Catalogue No.:PA 14 64000
CAS :
Molecular Formula : C28H22F3N7O
Molecular Weight : 529.52
3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline
Catalogue No.:PA 14 64510
Molecular Formula : C11H10F3N3
Molecular Weight : 241.21
3-Amino-4-methylbenzoic Acid
Catalogue No.:PA 14 64520
Molecular Formula : C8H9NO2
Molecular Weight : 151.16
4-Methyl-N-(3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
Catalogue No.:PA 14 64570
Nilotinib N-Oxide
Catalogue No.:PA 14 64600
Molecular Formula : C28H22F3N7O2
Molecular Weight : 545.53
4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
Catalogue No.:PA 14 64610
Molecular Formula : C17H15N5O
Molecular Weight : 305.34
Nilotinib 3-Pyridinyl Impurity
Catalogue No.:PA 14 0641005
Molecular Formula : C9H8N4
Molecular Weight : 172.19
(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
Catalogue No.:PA 14 0641012
Molecular Formula : C10H12N2O
Molecular Weight : 176.22
4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic Acid
Catalogue No.:PA 14 0641026
Molecular Formula : C17H13N5O3
Molecular Weight : 335.32
3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
Catalogue No.:PA 14 64530
4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole
Catalogue No.:PA 14 64540
Molecular Formula : C11H8F3N3O2
Molecular Weight : 271.2
4-Methyl-N-(3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide Hydrochloride
Catalogue No.:PA 14 64550
Molecular Formula : C28H23ClF3N7O
Molecular Weight : 565.98
3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Catalogue No.:PA 14 64560
Molecular Formula : C28H21ClF3N7O
Molecular Weight : 563.96
3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride
Catalogue No.:PA 14 64580
Molecular Formula : C12H13ClF3N3
Molecular Weight : 291.7
3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
Catalogue No.:PA 14 64590
Molecular Formula : C10H8F3N3
Molecular Weight : 227.19
3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3
Catalogue No.:PA STI 062190
Molecular Formula : C11H7D3F3N3
Molecular Weight : 244.23
3-Iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide-d3
Catalogue No.:PA STI 053340
Molecular Formula : C19H12D3F3IN3O
Molecular Weight : 488.26
Nilotinib-d3
Catalogue No.:PA STI 067760
Molecular Formula : C28H19D3F3N7O
Molecular Weight : 532.53
Nilotinib-d6
Catalogue No.:PA STI 067770
Molecular Formula : C28H16D6F3N7O
Molecular Weight : 535.55
1-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)ethan-1-one
Catalogue No.:PA 14 64630
Molecular Formula : C18H16N4O
Molecular Weight : 304.35
3-((5-Chloro-4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Catalogue No.:PA 14 64640
Molecular Weight : 563.97
3-Acetylpyridine N-Oxide
Catalogue No.:PA 14 64650
Molecular Formula : C7H7NO2
Molecular Weight : 137.14
3-[(Aminoiminomethyl)amino]-4-methylbenzoic Acid Ethyl Ester Mononitrate
Catalogue No.:PA 14 64660
Molecular Formula : C11H16N4O5
Molecular Weight : 284.27
3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Catalogue No.:PA 14 0641000
Molecular Formula : C12H12F3N3
Molecular Weight : 255.24
Nilotinib System Suitability Mixture
Catalogue No.:PA 14 0641001
Molecular Formula : NA
Molecular Weight : NA
3-Amino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Catalogue No.:PA 14 0641002
Molecular Formula : C19H17F3N4O
Molecular Weight : 374.37
3-Iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Catalogue No.:PA 14 0641003
Molecular Formula : C19H15F3IN3O
Molecular Weight : 485.25
4-(Pyridin-2-yl)pyrimidin-2-amine
Catalogue No.:PA 14 0641004
4-Methyl-N-(3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
Catalogue No.:PA 14 0641006
Molecular Weight : 529.53
Tert-butyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
Catalogue No.:PA 14 0641007
Molecular Formula : C21H22N4O2
Molecular Weight : 362.43
N-(3-(2,4-Dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
Catalogue No.:PA 14 0641008
Molecular Formula : C29H24F3N7O
Molecular Weight : 543.55
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile
Catalogue No.:PA 14 0641009
Molecular Formula : C12H8F3N3
Molecular Weight : 251.21
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide
Catalogue No.:PA 14 0641010
Molecular Formula : C12H10F3N3O
Molecular Weight : 269.23
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic acid
Catalogue No.:PA 14 0641011
Molecular Formula : C12H9F3N2O2
Molecular Weight : 270.21
3-Bromo-5-nitrobenzotrifluoride
Catalogue No.:PA 14 0641013
Molecular Formula : C7H3BrF3NO2
Molecular Weight : 270.01
4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-nitrobenzamide
Catalogue No.:PA 14 0641014
Molecular Formula : C19H15F3N4O3
Molecular Weight : 404.35
2,3-Dihydroxy-4-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)(4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-oxobutanoic acid
Catalogue No.:PA 14 0641015
Molecular Formula : C32H26F3N7O6
Molecular Weight : 661.6
3-Guanidino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Catalogue No.:PA 14 0641016
Molecular Formula : C20H19F3N6O
Molecular Weight : 416.41
tert-Butyl (3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamate
Catalogue No.:PA 14 0641018
Molecular Formula : C16H18F3N3O2
Molecular Weight : 341.33
3,5-Dinitrobenzotrifluoride
Catalogue No.:PA 14 0641017
Molecular Formula : C7H3F3N2O4
Molecular Weight : 236.11
Sodium 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
Catalogue No.:PA 14 0641019
Molecular Formula : C17H13N4NaO2
Molecular Weight : 328.31
4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
Catalogue No.:PA 14 0641020
Molecular Formula : C28H21F3N8O2
Molecular Weight : 558.53
4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3,5-bis((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide Hydrochloride
Catalogue No.:PA 14 0641021
Molecular Formula : C37H29ClF3N11O
Molecular Weight : 736.16
3-Amino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide Hydrochloride
Catalogue No.:PA 14 0641022
Molecular Formula : C19H18ClF3N4O
Molecular Weight : 410.83
3-(2-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Catalogue No.:PA 14 0641023
Molecular Weight : 241.22
3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile
Catalogue No.:PAI 14 064001
3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid
Catalogue No.:PAI 14 064002
tert-Butyl (3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamate
Catalogue No.:PAI 14 064003
Nilotinib Di N-Oxide
Catalogue No.:PA 14 0641024
Molecular Formula : C28H22F3N7O3
Molecular Weight : 561.53
Nilotinib Imidazolyl N-oxide
Catalogue No.:PA 14 0641025
Nilotinib Impurity A (Y0002103)
Catalogue No.:PA Y0002103
Nilotinib Impurity B (Y0002111)
Catalogue No.:PA Y0002111
Nilotinib Impurity C (Y0002108)
Catalogue No.:PA Y0002108
Nilotinib For System Suitability (Y0002100)
Catalogue No.:PA Y0002100
N-(3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide Hydrochloride
Catalogue No.:PA 14 0641027
Molecular Formula : C27H20ClF3N8O2
Molecular Weight : 580.96
3-(2,4-Dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Catalogue No.:PA 14 0641028
1,3-Bis(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)urea
Catalogue No.:PA 14 0641029
Molecular Formula : C23H18F6N6O
Molecular Weight : 508.43
3-(2-((2-Methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)(nitroso)amino)pyrimidin-4-yl)pyridine 1-oxide
Catalogue No.:PA 14 0641030
Molecular Formula : C28H21F3N8O3
Molecular Weight : 574.52
(E)-3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one
Catalogue No.:PA 14 0641031
3-Guanidino-4-methylbenzoic Acid
Catalogue No.:PA 14 0641032
Molecular Formula : C9H11N3O2
Molecular Weight : 193.21
Ethyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
Catalogue No.:PA 14 0641033
Molecular Formula : C19H18N4O2
Molecular Weight : 334.38
Nilotinib N-Oxide (Pyrimidine N3-Oxide)
Catalogue No.:PA 14 0641034
Nilotinib N-Oxide (Pyrimidine N1-Oxide)
Catalogue No.:PA 14 0641035
5-Amino-2-methylbenzoic Acid
Catalogue No.:PA 14 0641036
Molecular Weight : 151.17
3-Amino-2-methylbenzoic Acid
Catalogue No.:PA 14 0641037
3-Amino-5-methylbenzoic Acid
Catalogue No.:PA 14 0641038
3-(2-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Catalogue No.:PA 14 0641039
Ethyl 3-(3-(diaminomethylene)guanidino)-4-methylbenzoate
Catalogue No.:PA 14 0641040
Molecular Formula : C12H17N5O2
Molecular Weight : 263.3
3-(3-(3-((1E,2E)-3-Amino-1-(pyridin-3-yl)allylidene)guanidino)-4-methylbenzamido)-4-methylbenzoic Acid
Catalogue No.:PA 14 0641041
Molecular Formula : C25H24N6O3
Molecular Weight : 456.51
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