nilotinib hydrochloride and its Impurities

Nilotinib Hydrochloride is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib Hydrochloride API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.