Nalfurafine (INN, USAN) (brand name Remitch, former developmental code names TRK-820, AC-820, MT-9938) is an antipruritic (anti-itch drug) that is marketed in Japan for the treatment of uremic pruritus in individuals with chronic kidney disease undergoing hemodialysis. Reference standards of Nalfurafine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Nalfurafine
Catalogue No.:PA 14 1230000
CAS :
Molecular Formula : C28H32N2O5
Molecular Weight : 476.57
Nalfurafine hydrochloride
Catalogue No.:PA 14 1231000
Molecular Formula : C28H33ClN2O5
Molecular Weight : 513.03
10α-Hydroxy-nalfurafine
Catalogue No.:PA 14 1231001
Molecular Formula : C28H32N2O6
Molecular Weight : 492.57
2Z-Nalfurafine
Catalogue No.:PA 14 1231002
Descyclopropylmethyl Nalfurafine
Catalogue No.:PA 14 1231003
Molecular Formula : C24H26N2O5
Molecular Weight : 422.48
(4R,4aS,7S,7aR,12bS)-7-(Benzyl(methyl)amino)-3-(cyclopropylmethyl)-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
Catalogue No.:PA 14 1231004
Molecular Formula : C28H34N2O3
Molecular Weight : 446.59
(E)-N-((4R,4aS,7R,7aR,12bS,13S)-3-(Cyclopropylmethyl)-4a,9,13-trihydroxy-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl)-3-(furan-2-yl)-N-methylacrylamide
Catalogue No.:PA 14 1231005
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