Methotrexate Hydrate and its Impurities
Methotrexate (MTX), formerly known as amethopterin, it is an antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis. Reference standards of Methotrexate Hydrate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.