Methotrexate Disodium Salt and its Impurities

Methotrexate Disodium Salt, formerly known as amethopterin, is a chemotherapy agent and immune-system suppressant. It is used to treat cancer, autoimmune diseases, and ectopic pregnancies. Reference standards of Methotrexate Disodium Salt API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.