Melarsomine and its Impurities

Melarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide. It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection. Reference standards of Melarsomine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.