manidipine dihydrochloride and its Impurities

A potent calcium channel blocker, Manidipine is used as an antihypertensive drug. It suppresses proliferation and stimulates glycosaminoglycan synthesis in vitro. Reference standards of Manidipine Dihydrochloride API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.