Macitentan is used to treat high blood pressure in the lungs. It is sold under the brand name Opsumit. Reference standards of Macitentan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Macitentan
Catalogue No.:PA 13 79000
CAS :
Molecular Formula : C19H20Br2N6O4S
Molecular Weight : 588.27
tert-Butyl (N-propylsulfamoyl)carbamate
Catalogue No.:PA 13 79510
Molecular Formula : C8H18N2O4S
Molecular Weight : 238.30
5-(3-Bromophenyl)-4,6-dichloropyrimidine
Catalogue No.:PA 13 79520
Molecular Formula : C10H5BrCl2N2
Molecular Weight : 303.97
5-(2-Bromophenyl)-4,6-dichloropyrimidine
Catalogue No.:PA 13 79530
5-(4-Bromophenyl)-6-(vinyloxy)pyrimidin-4-amine
Catalogue No.:PA 13 79540
Molecular Formula : C12H10BrN3O
Molecular Weight : 292.13
2-((6-Amino-5-(4-bromophenyl)pyrimidin-4-yl)oxy)ethanol
Catalogue No.:PA 13 79550
Molecular Formula : C12H12BrN3O2
Molecular Weight : 310.15
5-(4-bromophenyl)-4-((N-propylsulfamoyl) amino)-6-(vinyloxy)pyrimidine
Catalogue No.:PA 13 79560
Molecular Formula : C15H17BrN4O3S
Molecular Weight : 413.29
6-Amino-5-(4-bromophenyl)pyrimidin-4-ol
Catalogue No.:PA 13 79570
Molecular Formula : C10H8BrN3O
Molecular Weight : 266.09
5-(4-Bromophenyl)-4-chloro-6-methoxypyrimidine
Catalogue No.:PA 13 79580
Molecular Formula : C11H8BrClN2O
Molecular Weight : 299.55
5-(4-Bromophenyl)-6-chloro-N-propylpyrimidin-4-amine
Catalogue No.:PA 13 79590
Molecular Formula : C13H13BrClN3
Molecular Weight : 326.62
2-((5-(4-bromophenyl)-6-chloropyrimidin-4-yl)oxy)ethanol
Catalogue No.:PA 13 79600
Molecular Formula : C12H10BrClN2O2
Molecular Weight : 329.58
Macitentan-d4
Catalogue No.:PA STI 057471
Molecular Formula : C19H16D4Br2N6O4S
Molecular Weight : 592.30
ACT 373898
Catalogue No.:PA 13 79610
Molecular Formula : C15H17BrN4O5S
Molecular Weight : 445.29
Despropylaminosulfonyl Macitentan
Catalogue No.:PA 13 79620
Molecular Formula : C16H13Br2N5O2
Molecular Weight : 467.12
Macitentan Dimer
Catalogue No.:PA 13 79630
Molecular Formula : C28H32Br2N8O6S2
Molecular Weight : 800.54
Macitentan Pyrimidine N-Propyl
Catalogue No.:PA 13 79640
Molecular Formula : C19H19Br2N5O2
Molecular Weight : 509.2
N-Despropyl Macitentan
Catalogue No.:PA 13 79650
Molecular Formula : C16H14Br2N6O4S
Molecular Weight : 546.19
2-((5-(4-Bromophenyl)-6-(propylamino)pyrimidin-4-yl)oxy)ethan-1-ol
Catalogue No.:PA 13 0791000
Molecular Formula : C15H18BrN3O2
Molecular Weight : 352.23
N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide
Catalogue No.:PA 13 0791001
Molecular Formula : C15H19BrN4O4S
Molecular Weight : 431.31
N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide
Catalogue No.:PA 13 0791002
Molecular Formula : C13H14BrClN4O2S
Molecular Weight : 405.7
Dimethyl 2-(4-bromophenyl)malonate
Catalogue No.:PA 13 0791003
Molecular Formula : C11H11BrO4
Molecular Weight : 287.11
5-(4-Bromophenyl)pyrimidine-4,6-diol
Catalogue No.:PA 13 0791004
Molecular Formula : C10H7BrN2O2
Molecular Weight : 267.08
5-Bromo-2-hydroxypyrimidine
Catalogue No.:PA 13 0791005
Molecular Formula : C4H3BrN2O
Molecular Weight : 174.99
5-Bromo-2-(2-chloroethoxy)pyrimidine
Catalogue No.:PA 13 0791006
Molecular Formula : C6H6BrClN2O
Molecular Weight : 237.48
5-(4-Bromophenyl)-6-methoxy-N-propylpyrimidin-4-amine
Catalogue No.:PA 13 0791007
Molecular Formula : C14H16BrN3O
Molecular Weight : 322.21
N-[5-(4-Hydroxyphenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsulfamide
Catalogue No.:PA 13 0791008
Molecular Formula : C13H16N4O4S
Molecular Weight : 324.36
5-(4-Bromophenyl)-6-(2-chloroethoxy)pyrimidin-4-amine
Catalogue No.:PA 13 0791009
Molecular Formula : C12H11BrClN3O
Molecular Weight : 328.59
O,O'-bis(5-Bromopyrimidin-2-yl)glycol
Catalogue No.:PA 13 0791010
Molecular Formula : C10H8Br2N4O2
Molecular Weight : 376.01
N-[5-(4-Bromophenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsulfamide
Catalogue No.:PA 13 0791011
Molecular Formula : C13H15BrN4O3S
Molecular Weight : 387.25
N-[5-(4-Bromophenyl)-6-vinyloxy-4-pyrimidinyl]-N'-propylsulfamide
Catalogue No.:PA 13 0791012
N-[5-(4-Bromophenyl)-6-[2-chloroethoxy]-4-pyrimidinyl]-N'-propylsulfamide
Catalogue No.:PA 13 0791013
Molecular Formula : C15H18BrClN4O3S
Molecular Weight : 449.75
5-des-Bromo-macitentan
Catalogue No.:PA 13 0791014
Molecular Formula : C19H21BrN6O4S
Molecular Weight : 509.38
5-desbromo-5-Chloro Macitentan
Catalogue No.:PA 13 0791015
Molecular Formula : C19H20BrClN6O4S
Molecular Weight : 543.82
S-Despropylamino S-Methyl Macitentan
Catalogue No.:PA 13 0791016
Molecular Formula : C17H15Br2N5O4S
Molecular Weight : 545.21
N-Despropyl-N-methyl Macitentan
Catalogue No.:PA 13 0791017
Molecular Formula : C17H16Br2N6O4S
Molecular Weight : 560.22
N-Despropyl-N-ethyl Macitentan
Catalogue No.:PA 13 0791018
Molecular Formula : C18H18Br2N6O4S
Molecular Weight : 574.25
Macitentan n-butyl analogue
Catalogue No.:PA 13 0791019
Molecular Formula : C20H21Br2N5O4S
Molecular Weight : 587.29
5-Bromo-2-chloropyrimidine
Catalogue No.:PA 13 0791020
Molecular Formula : C4H2BrClN2
Molecular Weight : 193.43
Macitentan 4-Chloro Analog
Catalogue No.:PA 13 0791021
N-[6-[2-[(5-Chloro -2-pyrimidinyl)oxy]ethoxy]-5-(4-chlorophenyl)-4-pyrimidinyl]-N’-propyl-sulfamide
Catalogue No.:PA 13 0791022
Molecular Formula : C19H20Cl2N6O4S
Molecular Weight : 499.37
4,6-Dichloro-5-(4-chlorophenyl)pyrimidine
Catalogue No.:PA 13 0791023
Molecular Formula : C10H5Cl3N2
Molecular Weight : 259.51
N-Nitroso Macitentan
Catalogue No.:PA 13 0791024
Molecular Formula : C19H19Br2N7O5S
Molecular Weight : 617.27
N-Nitroso Macitentan Dimer Impurity
Catalogue No.:PA 13 0791025
Molecular Formula : C28H30Br2N10O8S2
Molecular Weight : 858.54
N-Nitroso Pyrimidine Amine Impurity
Catalogue No.:PA 13 0791026
Molecular Formula : C13H13BrClN5O3S
Molecular Weight : 434.69
N-Nitroso Ethylene hydroxy Impurity
Catalogue No.:PA 13 0791027
Molecular Formula : C15H18BrN5O5S
Molecular Weight : 460.3
5-(4-bromophenyl)-4,6-dichloropyrimidine
Catalogue No.:PA 13 0791028
Macitentan Isopropyl Impurity
Catalogue No.:PA 13 0791029
Molecular Weight : 588.28
N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide
Catalogue No.:PA 13 0791031
N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide
Catalogue No.:PA 13 0791030
Molecular Formula : C12H12BrClN4O2S
Molecular Weight : 391.67
2-((5-Bromopyrimidin-2-yl)oxy)ethan-1-ol
Catalogue No.:PAI 13 079001
Molecular Formula : C6H7BrN2O2
Molecular Weight : 219.04
5-(4-Bromophenyl)-4-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)-6-chloropyrimidine
Catalogue No.:PAI 13 079002
Molecular Formula : C16H11Br2ClN4O2
Molecular Weight : 486.55
5-Bromo-2-Chloropyrimidine
Catalogue No.:PA BSC 07913684
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