Macitentan-impurities | Pharmaffiliates

macitentan and its Impurities

Macitentan is used to treat high blood pressure in the lungs. It is sold under the brand name Opsumit. Reference standards of Macitentan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 52 results for macitentan Impurities
PA 13 0791001

N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide

N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide


  • Catalogue No.:PA 13 0791001

  • CAS :

    1393813-43-8

  • Molecular Formula : C15H19BrN4O4S

  • Molecular Weight : 431.31

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PA 13 79000

Macitentan - API Standards

Macitentan


  • Catalogue No.:PA 13 79000

  • CAS :

    441798-33-0

  • Molecular Formula : C19H20Br2N6O4S

  • Molecular Weight : 588.27

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PA 13 79620

Despropylaminosulfonyl Macitentan

Despropylaminosulfonyl Macitentan


  • Catalogue No.:PA 13 79620

  • CAS :

    1433875-21-8

  • Molecular Formula : C16H13Br2N5O2

  • Molecular Weight : 467.12

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PA 13 79640

Macitentan Pyrimidine N-Propyl

Macitentan Pyrimidine N-Propyl


  • Catalogue No.:PA 13 79640

  • CAS :

    NA

  • Molecular Formula : C19H19Br2N5O2

  • Molecular Weight : 509.2

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PA 13 79510

tert-Butyl (N-propylsulfamoyl)carbamate

tert-Butyl (N-propylsulfamoyl)carbamate


  • Catalogue No.:PA 13 79510

  • CAS :

    1393813-40-5

  • Molecular Formula : C8H18N2O4S

  • Molecular Weight : 238.30

PA 13 79520

5-(3-Bromophenyl)-4,6-dichloropyrimidine

5-(3-Bromophenyl)-4,6-dichloropyrimidine


  • Catalogue No.:PA 13 79520

  • CAS :

    1532412-37-5

  • Molecular Formula : C10H5BrCl2N2

  • Molecular Weight : 303.97

PA 13 79530

5-(2-Bromophenyl)-4,6-dichloropyrimidine

5-(2-Bromophenyl)-4,6-dichloropyrimidine


  • Catalogue No.:PA 13 79530

  • CAS :

    1516860-25-5

  • Molecular Formula : C10H5BrCl2N2

  • Molecular Weight : 303.97

PA 13 79540

5-(4-Bromophenyl)-6-(vinyloxy)pyrimidin-4-amine

5-(4-Bromophenyl)-6-(vinyloxy)pyrimidin-4-amine


  • Catalogue No.:PA 13 79540

  • CAS :

    2211054-17-8

  • Molecular Formula : C12H10BrN3O

  • Molecular Weight : 292.13

PA 13 79550

2-((6-Amino-5-(4-bromophenyl)pyrimidin-4-yl)oxy)ethanol

2-((6-Amino-5-(4-bromophenyl)pyrimidin-4-yl)oxy)ethanol


  • Catalogue No.:PA 13 79550

  • CAS :

    2211059-05-9

  • Molecular Formula : C12H12BrN3O2

  • Molecular Weight : 310.15

PA 13 79560

5-(4-bromophenyl)-4-((N-propylsulfamoyl) amino)-6-(vinyloxy)pyrimidine

5-(4-bromophenyl)-4-((N-propylsulfamoyl) amino)-6-(vinyloxy)pyrimidine


  • Catalogue No.:PA 13 79560

  • CAS :

    NA

  • Molecular Formula : C15H17BrN4O3S

  • Molecular Weight : 413.29

PA 13 79570

6-Amino-5-(4-bromophenyl)pyrimidin-4-ol

6-Amino-5-(4-bromophenyl)pyrimidin-4-ol


  • Catalogue No.:PA 13 79570

  • CAS :

    2211054-46-3

  • Molecular Formula : C10H8BrN3O

  • Molecular Weight : 266.09

PA 13 79580

5-(4-Bromophenyl)-4-chloro-6-methoxypyrimidine

5-(4-Bromophenyl)-4-chloro-6-methoxypyrimidine


  • Catalogue No.:PA 13 79580

  • CAS :

    2518002-08-7

  • Molecular Formula : C11H8BrClN2O

  • Molecular Weight : 299.55

PA 13 79590

5-(4-Bromophenyl)-6-chloro-N-propylpyrimidin-4-amine

5-(4-Bromophenyl)-6-chloro-N-propylpyrimidin-4-amine


  • Catalogue No.:PA 13 79590

  • CAS :

    2514735-21-6

  • Molecular Formula : C13H13BrClN3

  • Molecular Weight : 326.62

PA 13 79600

2-((5-(4-bromophenyl)-6-chloropyrimidin-4-yl)oxy)ethanol

2-((5-(4-bromophenyl)-6-chloropyrimidin-4-yl)oxy)ethanol


  • Catalogue No.:PA 13 79600

  • CAS :

    1642873-04-8

  • Molecular Formula : C12H10BrClN2O2

  • Molecular Weight : 329.58

PA STI 057471

Macitentan-d4

Macitentan-d4


  • Catalogue No.:PA STI 057471

  • CAS :

    1258428-05-5

  • Molecular Formula : C19H16D4Br2N6O4S

  • Molecular Weight : 592.30

PA 13 79610

ACT 373898

ACT 373898


  • Catalogue No.:PA 13 79610

  • CAS :

    1433875-14-9

  • Molecular Formula : C15H17BrN4O5S

  • Molecular Weight : 445.29

PA 13 79630

Macitentan Dimer

Macitentan Dimer


  • Catalogue No.:PA 13 79630

  • CAS :

    2089065-77-8

  • Molecular Formula : C28H32Br2N8O6S2

  • Molecular Weight : 800.54

PA 13 79650

Aprocitentan - API Standards

Aprocitentan


  • Catalogue No.:PA 13 79650

  • CAS :

    1103522-45-7

  • Molecular Formula : C16H14Br2N6O4S

  • Molecular Weight : 546.19

PA 13 0791000

2-((5-(4-Bromophenyl)-6-(propylamino)pyrimidin-4-yl)oxy)ethan-1-ol

2-((5-(4-Bromophenyl)-6-(propylamino)pyrimidin-4-yl)oxy)ethan-1-ol


  • Catalogue No.:PA 13 0791000

  • CAS :

    NA

  • Molecular Formula : C15H18BrN3O2

  • Molecular Weight : 352.23

PA 13 0791002

N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide

N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide


  • Catalogue No.:PA 13 0791002

  • CAS :

    1393813-42-7

  • Molecular Formula : C13H14BrClN4O2S

  • Molecular Weight : 405.7

PA 13 0791003

Dimethyl 2-(4-bromophenyl)malonate

Dimethyl 2-(4-bromophenyl)malonate


  • Catalogue No.:PA 13 0791003

  • CAS :

    149506-35-4

  • Molecular Formula : C11H11BrO4

  • Molecular Weight : 287.11

PA 13 0791004

5-(4-Bromophenyl)pyrimidine-4,6-diol

5-(4-Bromophenyl)pyrimidine-4,6-diol


  • Catalogue No.:PA 13 0791004

  • CAS :

    706811-25-8

  • Molecular Formula : C10H7BrN2O2

  • Molecular Weight : 267.08

PA 13 0791005

5-Bromo-2-hydroxypyrimidine

5-Bromo-2-hydroxypyrimidine


  • Catalogue No.:PA 13 0791005

  • CAS :

    38353-06-9

  • Molecular Formula : C4H3BrN2O

  • Molecular Weight : 174.99

PA 13 0791006

5-Bromo-2-(2-chloroethoxy)pyrimidine

5-Bromo-2-(2-chloroethoxy)pyrimidine


  • Catalogue No.:PA 13 0791006

  • CAS :

    2365406-84-2

  • Molecular Formula : C6H6BrClN2O

  • Molecular Weight : 237.48

PA 13 0791007

5-(4-Bromophenyl)-6-methoxy-N-propylpyrimidin-4-amine

5-(4-Bromophenyl)-6-methoxy-N-propylpyrimidin-4-amine


  • Catalogue No.:PA 13 0791007

  • CAS :

    NA

  • Molecular Formula : C14H16BrN3O

  • Molecular Weight : 322.21

PA 13 0791008

N-[5-(4-Hydroxyphenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsulfamide

N-[5-(4-Hydroxyphenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsulfamide


  • Catalogue No.:PA 13 0791008

  • CAS :

    NA

  • Molecular Formula : C13H16N4O4S

  • Molecular Weight : 324.36

PA 13 0791009

5-(4-Bromophenyl)-6-(2-chloroethoxy)pyrimidin-4-amine

5-(4-Bromophenyl)-6-(2-chloroethoxy)pyrimidin-4-amine


  • Catalogue No.:PA 13 0791009

  • CAS :

    2365406-86-4

  • Molecular Formula : C12H11BrClN3O

  • Molecular Weight : 328.59

PA 13 0791010

O,O'-bis(5-Bromopyrimidin-2-yl)glycol

O,O'-bis(5-Bromopyrimidin-2-yl)glycol


  • Catalogue No.:PA 13 0791010

  • CAS :

    2211054-90-7

  • Molecular Formula : C10H8Br2N4O2

  • Molecular Weight : 376.01

PA 13 0791011

N-[5-(4-Bromophenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsulfamide

N-[5-(4-Bromophenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsulfamide


  • Catalogue No.:PA 13 0791011

  • CAS :

    2365406-85-3

  • Molecular Formula : C13H15BrN4O3S

  • Molecular Weight : 387.25

PA 13 0791012

N-[5-(4-Bromophenyl)-6-vinyloxy-4-pyrimidinyl]-N'-propylsulfamide

N-[5-(4-Bromophenyl)-6-vinyloxy-4-pyrimidinyl]-N'-propylsulfamide


  • Catalogue No.:PA 13 0791012

  • CAS :

    NA

  • Molecular Formula : C15H17BrN4O3S

  • Molecular Weight : 413.29

PA 13 0791013

N-[5-(4-Bromophenyl)-6-[2-chloroethoxy]-4-pyrimidinyl]-N'-propylsulfamide

N-[5-(4-Bromophenyl)-6-[2-chloroethoxy]-4-pyrimidinyl]-N'-propylsulfamide


  • Catalogue No.:PA 13 0791013

  • CAS :

    2365406-87-5

  • Molecular Formula : C15H18BrClN4O3S

  • Molecular Weight : 449.75

PA 13 0791014

5-des-Bromo-macitentan

5-des-Bromo-macitentan


  • Catalogue No.:PA 13 0791014

  • CAS :

    2211059-00-4

  • Molecular Formula : C19H21BrN6O4S

  • Molecular Weight : 509.38

PA 13 0791015

5-desbromo-5-Chloro Macitentan

5-desbromo-5-Chloro Macitentan


  • Catalogue No.:PA 13 0791015

  • CAS :

    2443747-63-3

  • Molecular Formula : C19H20BrClN6O4S

  • Molecular Weight : 543.82

PA 13 0791016

S-Despropylamino S-Methyl Macitentan

S-Despropylamino S-Methyl Macitentan


  • Catalogue No.:PA 13 0791016

  • CAS :

    556796-88-4

  • Molecular Formula : C17H15Br2N5O4S

  • Molecular Weight : 545.21

PA 13 0791017

N-Despropyl-N-methyl Macitentan

N-Despropyl-N-methyl Macitentan


  • Catalogue No.:PA 13 0791017

  • CAS :

    441798-25-0

  • Molecular Formula : C17H16Br2N6O4S

  • Molecular Weight : 560.22

PA 13 0791018

N-Despropyl-N-ethyl Macitentan

N-Despropyl-N-ethyl Macitentan


  • Catalogue No.:PA 13 0791018

  • CAS :

    441796-13-0

  • Molecular Formula : C18H18Br2N6O4S

  • Molecular Weight : 574.25

PA 13 0791019

Macitentan n-butyl analogue

Macitentan n-butyl analogue


  • Catalogue No.:PA 13 0791019

  • CAS :

    556797-16-1

  • Molecular Formula : C20H21Br2N5O4S

  • Molecular Weight : 587.29

PA 13 0791020

5-Bromo-2-chloropyrimidine

5-Bromo-2-chloropyrimidine


  • Catalogue No.:PA 13 0791020

  • CAS :

    32779-36-5

  • Molecular Formula : C4H2BrClN2

  • Molecular Weight : 193.43

PA 13 0791021

Macitentan 4-Chloro Analog

Macitentan 4-Chloro Analog


  • Catalogue No.:PA 13 0791021

  • CAS :

    441798-36-3

  • Molecular Formula : C19H20BrClN6O4S

  • Molecular Weight : 543.82

PA 13 0791022

N-[6-[2-[(5-Chloro -2-pyrimidinyl)oxy]ethoxy]-5-(4-chlorophenyl)-4-pyrimidinyl]-N’-propyl-sulfamide

N-[6-[2-[(5-Chloro -2-pyrimidinyl)oxy]ethoxy]-5-(4-chlorophenyl)-4-pyrimidinyl]-N’-propyl-sulfamide


  • Catalogue No.:PA 13 0791022

  • CAS :

    NA

  • Molecular Formula : C19H20Cl2N6O4S

  • Molecular Weight : 499.37

PA 13 0791023

4,6-Dichloro-5-(4-chlorophenyl)pyrimidine

4,6-Dichloro-5-(4-chlorophenyl)pyrimidine


  • Catalogue No.:PA 13 0791023

  • CAS :

    3974-18-3

  • Molecular Formula : C10H5Cl3N2

  • Molecular Weight : 259.51

PA 13 0791024

N-Nitroso Macitentan

N-Nitroso Macitentan


  • Catalogue No.:PA 13 0791024

  • CAS :

    NA

  • Molecular Formula : C19H19Br2N7O5S

  • Molecular Weight : 617.27

PA 13 0791025

N-Nitroso Macitentan Dimer Impurity

N-Nitroso Macitentan Dimer Impurity


  • Catalogue No.:PA 13 0791025

  • CAS :

    NA

  • Molecular Formula : C28H30Br2N10O8S2

  • Molecular Weight : 858.54

PA 13 0791026

N-Nitroso Pyrimidine Amine Impurity

N-Nitroso Pyrimidine Amine Impurity


  • Catalogue No.:PA 13 0791026

  • CAS :

    NA

  • Molecular Formula : C13H13BrClN5O3S

  • Molecular Weight : 434.69

PA 13 0791027

N-Nitroso Ethylene hydroxy Impurity

N-Nitroso Ethylene hydroxy Impurity


  • Catalogue No.:PA 13 0791027

  • CAS :

    NA

  • Molecular Formula : C15H18BrN5O5S

  • Molecular Weight : 460.3

PA 13 0791028

5-(4-bromophenyl)-4,6-dichloropyrimidine

5-(4-bromophenyl)-4,6-dichloropyrimidine


  • Catalogue No.:PA 13 0791028

  • CAS :

    146533-41-7

  • Molecular Formula : C10H5BrCl2N2

  • Molecular Weight : 303.97

PA 13 0791029

Macitentan Isopropyl Impurity

Macitentan Isopropyl Impurity


  • Catalogue No.:PA 13 0791029

  • CAS :

    NA

  • Molecular Formula : C19H20Br2N6O4S

  • Molecular Weight : 588.28

PA 13 0791031

N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide

N-[6-[2-[(5-Bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N′-propylsulfamide


  • Catalogue No.:PA 13 0791031

  • CAS :

    2300968-87-8

  • Molecular Formula : C19H21BrN6O4S

  • Molecular Weight : 509.38

PA 13 0791030

N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide

N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide


  • Catalogue No.:PA 13 0791030

  • CAS :

    441797-83-7

  • Molecular Formula : C12H12BrClN4O2S

  • Molecular Weight : 391.67

PAI 13 079001

2-((5-Bromopyrimidin-2-yl)oxy)ethan-1-ol

2-((5-Bromopyrimidin-2-yl)oxy)ethan-1-ol


  • Catalogue No.:PAI 13 079001

  • CAS :

    1246922-88-2

  • Molecular Formula : C6H7BrN2O2

  • Molecular Weight : 219.04

PAI 13 079002

5-(4-Bromophenyl)-4-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)-6-chloropyrimidine

5-(4-Bromophenyl)-4-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)-6-chloropyrimidine


  • Catalogue No.:PAI 13 079002

  • CAS :

    1642873-05-9

  • Molecular Formula : C16H11Br2ClN4O2

  • Molecular Weight : 486.55

PA BSC 07913684

5-Bromo-2-Chloropyrimidine (BSC)

5-Bromo-2-Chloropyrimidine


  • Catalogue No.:PA BSC 07913684

  • CAS :

    32779-36-5

  • Molecular Formula : C4H2BrClN2

  • Molecular Weight : 193.43