Lubiprostone used in the management of idiopathic chronic constipation. It is sold under the trade name Amitiza. Reference standards of Lubiprostone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Lubiprostone
Catalogue No.:PA 12 87000
CAS :
Molecular Formula : C20H32F2O5
Molecular Weight : 390.46
7-((2S,4aS,5S,7aS)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic Acid
Catalogue No.:PA 12 87510
Lubiprostone (Mixture of Tautomeric Isomers)
Catalogue No.:PA 12 87520
Molecular Formula : C40H64F4O10
Molecular Weight : 780.94
7-((1S,2R,5R,8S)-2-(1,1-Difluoropentyl)-2,8-dihydroxy-7-oxobicyclo[3.2.1]octan-6-yl)heptanoic Acid
Catalogue No.:PA 12 87540
15-Hydroxy Lubiprostone Dicyclohexylammonium Salt-d7
Catalogue No.:PA STI 049600
Molecular Formula : C32H50D7F2NO5
Molecular Weight : 580.84
15-Hydroxy Lubiprostone Phenylmethyl Ester-d7 (Mixture of Diastereomers)
Catalogue No.:PA STI 049610
Molecular Formula : C27H33D7F2O5
Molecular Weight : 489.64
Lubiprostone-d9
Catalogue No.:PA STI 057250
Molecular Formula : C20H23D9F2O5
Molecular Weight : 399.52
Lubiprostone-d7
Catalogue No.:PA STI 057260
Molecular Formula : C20H25D7F2O5
Molecular Weight : 397.51
11-O-Tetrahydropyranyl-15-O-tert-butyldimethylsilyl-lubiprostone-d7 Phenylmethyl Ester
Catalogue No.:PA STI 082200
Molecular Formula : C38H55D7F2O6Si
Molecular Weight : 688.02
O-Tetrahydropyranyl Lubiprostone-d7
Catalogue No.:PA STI 082230
Molecular Formula : C25H33D7F2O6
Molecular Weight : 481.62
(7α,11)-Dihydroxy-5-keto-12,12-difluorotetranorprosta-1,16-dioic Acid
Catalogue No.:PA 12 87550
Molecular Formula : C16H24F2O7
Molecular Weight : 366.36
15-Hydroxy Lubiprostone
Catalogue No.:PA 12 87560
Molecular Formula : C20H34F2O5
Molecular Weight : 392.48
7-((1R,2R,3R)-3-(Benzyloxy)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl)heptanoic Acid
Catalogue No.:PA 12 0871000
Molecular Formula : C27H38F2O5
Molecular Weight : 480.58
7-((1R,2S)-2-(4,4-Difluoro-3-oxooctyl)-5-oxocyclopent-3-en-1-yl)heptanoic Acid
Catalogue No.:PA 12 0871001
Molecular Formula : C20H30F2O4
Molecular Weight : 372.45
7-((2R,4aR,5S,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic Acid
Catalogue No.:PA 12 0871002
Molecular Weight : 390.47
7-(3-(1,1-difluoropentyl)-3-hydroxy-4-oxo-1,2,3,3a,4,6a-hexahydropentalen-3a-yl)heptanoic acid
Catalogue No.:PA 12 0871003
7-(2-(1,1-Difluoropentyl)-2,8-dihydroxy-7-oxobicyclo[3.2.1]octan-6-yl)heptanoic acid
Catalogue No.:PA 12 0871004
(3aR,4R,5R,6aS)-2-oxo-5-((Tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-4-carbaldehyde
Catalogue No.:PA 12 0871005
Molecular Formula : C13H18O5
Molecular Weight : 254.28
(3AR,4S,5R,6aS)-4-(Hydroxymethyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one
Catalogue No.:PA 12 0871006
Molecular Formula : C13H20O5
Molecular Weight : 256.3
rel-(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one
Catalogue No.:PA 12 0871009
Molecular Formula : C8H12O4
Molecular Weight : 172.18
7-((1R,2R,3S)-2-(4,4-difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid
Catalogue No.:PA 12 0871007
7-((1R,2R,3R)-2-(4,4-difluoro-3-hydroxyoctyl-6,6,7,7,8,8,8-d7)-3-hydroxy-5-oxocyclopentyl)heptanoic acid
Catalogue No.:PA STI 088979
Molecular Formula : C20H27D7F2O5
Molecular Weight : 399.53
7-((1R,2R,3R)-2-(4,4-Difluoro-3-hydroxyoctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic-3,3,4,4-d4 acid
Catalogue No.:PA STI 088977
Molecular Formula : C20H30D4F2O5
Molecular Weight : 396.51
7-((1S,2R,3R)-2-(4,4-Difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid
Catalogue No.:PA 12 0871008
Lubiprostone hemiketal
Catalogue No.:PA 12 0871010
O-Tetrahydropyranyl Lubiprostone
Catalogue No.:PA 12 0871011
Molecular Formula : C25H40F2O6
Molecular Weight : 474.59
Cyclohexylmethyl 7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoate
Catalogue No.:PA 12 0871012
Molecular Formula : C27H44F2O5
Molecular Weight : 486.64
Benzyl (Z)-7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)hept-5-enoate
Catalogue No.:PA 12 0871013
Molecular Formula : C27H36F2O5
Molecular Weight : 478.58
7-((1R,2R)-2-(4,4-Difluoro-3-oxooctyl)-5-oxocyclopent-3-en-1-yl)heptanamide
Catalogue No.:PA 12 0871014
Molecular Formula : C20H31F2NO3
Molecular Weight : 371.47
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