Levosimendan is marketed under the trade name Simdax. It is a calcium sensitiser used in the management of acutely decompensated congestive heart failure. Reference standards of Levosimendan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Levosimendan
Catalogue No.:PA 12 42000
CAS :
Molecular Formula : C14H12N6O
Molecular Weight : 280.28
Levosimendan Cyanoacetate Hydrazone Impurity
Catalogue No.:PA 12 42520
Molecular Formula : C16H17N5O3
Molecular Weight : 327.34
Levosimendan Triazene Impurity
Catalogue No.:PA 12 42530
Molecular Formula : C22H23N7O2
Molecular Weight : 417.46
6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one
Catalogue No.:PA 12 42570
Molecular Formula : C11H13N3O
Molecular Weight : 203.25
2-[2-[4-(2-Azidotetrahydro-3-methyl-5-oxo-2-furanyl)phenyl]hydrazinylidene]propanedinitrile
Catalogue No.:PA 12 42510
Molecular Formula : C14H11N7O2
Molecular Weight : 309.28
(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide
Catalogue No.:PA 12 42540
Levosimendan Cyanoacetamide Hydrazone Impurity
Catalogue No.:PA 12 42550
Molecular Formula : C14H14N6O2
Molecular Weight : 298.31
4-Amino-6-ethoxy-N-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-5-((4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)pyrimidine-2-carbohydrazonoyl cyanide
Catalogue No.:PA 12 42560
Molecular Formula : C30H30N12O3
Molecular Weight : 606.65
2-Amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl Cyanide
Catalogue No.:PA 12 42580
Dextrosimendan
Catalogue No.:PA 12 42590
Molecular Weight : 280.29
(R)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone
Catalogue No.:PA 12 0421000
(S)-5-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one
Catalogue No.:PA 12 0421001
Molecular Formula : C11H12N2O
Molecular Weight : 188.23
(E)-2-(4-((E)-Isocyano(2-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)methyl)-2H-1,3-oxazet-2-ylidene)-2-((E)-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)acetonitrile
Catalogue No.:PA 12 0421002
Molecular Formula : C28H23N11O3
Molecular Weight : 561.57
(R,Z)-2-Amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide
Catalogue No.:PA 12 0421003
4-(4-(2-(Dicyanomethylene)hydrazinyl)phenyl)-3-methyl-4-oxobutanoic Acid
Catalogue No.:PA 12 0421004
Molecular Formula : C14H12N4O3
Molecular Weight : 284.28
(R)-N-Acetyl-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone
Catalogue No.:PA 12 0421005
Molecular Formula : C13H15N3O2
Molecular Weight : 245.28
Methyl (R,E)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)acetate
Catalogue No.:PA 12 0421006
Molecular Formula : C15H15N5O3
Molecular Weight : 313.32
(R)-N'-(Dicyanomethylene)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)nitrous Hydrazide
Catalogue No.:PA 12 0421007
Molecular Weight : 309.29
(R,E)-2-Amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl Cyanide
Catalogue No.:PA 12 0421008
N-(4-(2-Chloropropanoyl)phenyl)acetamide
Catalogue No.:PA 12 0421009
Molecular Formula : C11H12ClNO2
Molecular Weight : 225.67
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