Lapatinib Ditosylate Hydrate is used in combination therapy for HER2-positive breast cancer. It is used for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2. Reference standards of Lapatinib Ditosylate Hydrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Lapatinib Ditosylate Hydrate
Catalogue No.:PA 39 05000
CAS :
Molecular Formula : C43H44ClFN4O11S3
Molecular Weight : 943.48
Deschloro Lapatinib
Catalogue No.:PA 39 0051004
Molecular Formula : C29H27FN4O4S
Molecular Weight : 546.62
N-(4-((3-Fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate)
Catalogue No.:PA 39 0051006
Molecular Formula : C43H43FN4O10S3
Molecular Weight : 891.01
O-De(3-fluorobenzyl) Lapatinib
Catalogue No.:PA 39 05510
Molecular Formula : C22H21ClN4O4S
Molecular Weight : 472.94
N-De[2-(methylsulfonyl)ethyl] Lapatinib
Catalogue No.:PA 39 05520
Molecular Formula : C26H20ClFN4O2
Molecular Weight : 474.91
5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carboxylic Acid
Catalogue No.:PA 39 05530
Molecular Formula : C26H17ClFN3O4
Molecular Weight : 489.88
Des(sulfonylethyl)amino Hydroxy Lapatinib
Catalogue No.:PA 39 05540
Molecular Formula : C26H19ClFN3O3
Molecular Weight : 475.9
5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde
Catalogue No.:PA 39 05550
Molecular Formula : C26H17ClFN3O3
Molecular Weight : 473.89
N-(3-Chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
Catalogue No.:PA 39 0051000
Molecular Formula : C29H26ClFN4O4S
Molecular Weight : 581.06
N-(4-(4-Fluorobenzyloxy)-3-chlorophenyl)-6-(5-((2-(methylsulfonyl)ethylamino) methyl)furan-2-yl)quinazolin-4-amine
Catalogue No.:PA 39 0051001
3-Chloro-4-(3-fluorobenzyloxy)aniline
Catalogue No.:PA 39 0051002
Molecular Formula : C13H11ClFNO
Molecular Weight : 251.69
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine
Catalogue No.:PA 39 0051005
Molecular Formula : C21H14ClFIN3O
Molecular Weight : 505.72
4-((3-Fluorobenzyl)oxy)aniline
Catalogue No.:PAI 39 005001
Molecular Formula : C13H12FNO
Molecular Weight : 217.24
4-((3-Fluorobenzyl)oxy)aniline Hydrochloride
Catalogue No.:PAI 39 005002
Molecular Formula : C13H13ClFNO
Molecular Weight : 253.7
N-(4-((3-Fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine
Catalogue No.:PAI 39 005003
Molecular Formula : C21H15FIN3O
Molecular Weight : 471.27
5-(4-((4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde
Catalogue No.:PAI 39 005004
Molecular Formula : C26H18FN3O3
Molecular Weight : 439.45
N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-((((5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-yl)methyl)(2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
Catalogue No.:PA 39 0051008
Molecular Formula : C55H43Cl2F2N7O6S
Molecular Weight : 1038.95
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