kynurenine and its Impurities

Kynurenine is synthesized by the enzyme tryptophan dioxygenase, which is made primarily but not exclusively in the liver, and indoleamine 2,3-dioxygenase, which is made in many tissues in response to immune activation. It is a metabolite of the amino acid. Reference standards of Kynurenine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.