Ivabradine Hydrochloride is used for the symptomatic treatment of chronic stable angina pectoris in patients with normal sinus rhythm who cannot take beta blockers. It is marketed under the trade name Corlanor. Reference standards of Ivabradine Hydrochloride API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Ivabradine Hydrochloride
Catalogue No.:PA 09 24000
CAS :
Molecular Formula : C27H37ClN2O5
Molecular Weight : 505.05
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride
Catalogue No.:PA 09 24650
Molecular Formula : C12H18ClNO2
Molecular Weight : 243.73
3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one
Catalogue No.:PA 09 24720
Molecular Formula : C15H18ClNO3
Molecular Weight : 295.76
Homoveratric Acid
Catalogue No.:PA 09 24920
Molecular Formula : C10H12O4
Molecular Weight : 196.2
Dehydro Ivabradine
Catalogue No.:PA 09 24510
Molecular Formula : C27H34N2O5
Molecular Weight : 466.57
N-Demethyl Ivabradine Hydrochloride
Catalogue No.:PA 09 24520
Molecular Formula : C26H35ClN2O5
Molecular Weight : 491.02
O-Desmethyl Ivabradine
Catalogue No.:PA 09 24530
Molecular Formula : C26H34N2O5
Molecular Weight : 454.56
8-Demethyl Ivabradine
Catalogue No.:PA 09 24540
Ivabradin N-oxide
Catalogue No.:PA 09 24550
Molecular Formula : C27H36N2O6
Molecular Weight : 484.6
Acetyl Ivabradine
Catalogue No.:PA 09 24560
Molecular Formula : C14H19NO3
Molecular Weight : 249.31
Hydroxy Ivabradine
Catalogue No.:PA 09 24570
Molecular Formula : C15H21NO4
Molecular Weight : 279.33
Ivabradine R-Isomer
Catalogue No.:PA 09 24580
Molecular Formula : C27H36N2O5
Molecular Weight : 468.59
(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine
Catalogue No.:PA 09 24590
Molecular Formula : C11H15NO2
Molecular Weight : 193.24
(7R)-3,4-dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Hydrochloride
Catalogue No.:PA 09 24600
N-(2,2-Dimethoxyethyl)-2-(3,4-dimethoxyphenyl)acetamide
Catalogue No.:PA 09 24610
Molecular Formula : C14H21NO5
Molecular Weight : 283.32
Ivabradine R-Isomer Hydrochloride
Catalogue No.:PA 09 24620
2-Oxo-ivabradine Hydrochloride
Catalogue No.:PA 09 24630
Molecular Formula : C27H35ClN2O6
Molecular Weight : 519.03
3-(3-Iodopropyl)-7,8-dimethoxy-1H-3-benzazepin-2-one
Catalogue No.:PA 09 24640
Molecular Formula : C15H18INO3
Molecular Weight : 387.21
(R)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine
Catalogue No.:PA 09 24660
Molecular Formula : C12H17NO2
Molecular Weight : 207.27
(RS)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine
Catalogue No.:PA 09 24670
(S)-Ethyl ((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)carbamate
Catalogue No.:PA 09 24680
Molecular Formula : C14H19NO4
Molecular Weight : 265.3
(S)-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine
Catalogue No.:PA 09 24690
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
Catalogue No.:PA 09 24710
Molecular Formula : C12H13NO3
Molecular Weight : 219.24
(S)-2-(2-(2-((3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)amino)ethyl)-4,5-dimethoxyphenyl)acetic Acid
Catalogue No.:PA 09 24730
Molecular Formula : C27H38N2O6
Molecular Weight : 486.61
(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-4-hydroxy-7,8-dimethoxy-5-oxo-2,5-dihydro-1H-benzo[d]azepin-3-ium
Catalogue No.:PA 09 24740
Molecular Formula : C27H35N2O6+
Molecular Weight : 483.58
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Catalogue No.:PA 09 24750
Molecular Formula : C11H11NO2
Molecular Weight : 189.21
Ethyl [(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl] imidoformate
Catalogue No.:PA 09 24760
(S)-3,3'-((((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)azanediyl)bis(propane-3,1-diyl))bis(7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one) Hydrochloride
Catalogue No.:PA 09 24770
Molecular Formula : C41H54ClN3O8
Molecular Weight : 752.34
N-Demethyl Ivabradine
Catalogue No.:PA 09 24780
Molecular Weight : 454.6
Methyl (S)-2-(2-(2-((3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)amino)ethyl)-4,5-dimethoxyphenyl)Acetate
Catalogue No.:PA 09 24790
Molecular Formula : C28H40N2O6
Molecular Weight : 500.63
(S)-3-(3-((3-Chloro-2-(3,4-dimethoxyphenyl)propyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 24800
(S)-2-(2-(2-((3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)amino)ethyl)-4,5-dimethoxyphenyl)-2-oxoacetic Acid
Catalogue No.:PA 09 24810
Molecular Formula : C27H36N2O7
Molecular Weight : 500.58
3,3’-(Propane-1,3-diyl)bis(7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one)
Catalogue No.:PA 09 24820
Molecular Formula : C27H34N2O6
Molecular Weight : 482.58
(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-2,3-dihydro-1H-benzo[d]azepine-1,4(5H)-dione
Catalogue No.:PA 09 24830
Molecular Weight : 482.24
3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-1-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 24840
Molecular Weight : 484.59
1-Chloro-2-(2-(2-((3-(((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)amino)-2-hydroxyethyl)-4,5-dimethoxyphenyl)ethan-1-ol
Catalogue No.:PA 09 24850
Molecular Formula : C27H39ClN2O6
Molecular Weight : 523.07
(E)-1-Chloro-2-(2-(2-((3-(((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)imino)ethyl)-4,5-dimethoxyphenyl)ethan-1-ol
Catalogue No.:PA 09 24860
3-Chloro-2-(3,4-dimethoxyphenyl)-N-methylpropan-1-amine Hydrochloride
Catalogue No.:PA 09 24870
Molecular Formula : C12H19Cl2NO2
Molecular Weight : 280.19
(R)-3,4-Dimethoxy-N-methylbicyclo[4.2.0]octa-1,3,5-triene-7-carboxamide
Catalogue No.:PA 09 24880
Molecular Formula : C12H15NO3
Molecular Weight : 221.26
Dehydro Ivabradine Hydrochloride
Catalogue No.:PA 09 24890
Molecular Formula : C27H35ClN2O5
Molecular Weight : 503.04
3-(3-Bromopropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 24900
Molecular Formula : C15H18BrNO3
Molecular Weight : 340.22
(S)-3-(3-((2-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)ethyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione Hydrochloride
Catalogue No.:PA 09 24910
Molecular Weight : 519.04
7,8-Dimethoxy-3-propyl-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 24930
Molecular Formula : C15H21NO3
Molecular Weight : 263.34
3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
Catalogue No.:PA 09 24940
Molecular Formula : C15H20ClNO3
Molecular Weight : 297.78
3,3'-(Propane-1,3-diyl)bis(7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one)
Catalogue No.:PA 09 24950
Molecular Formula : C27H30N2O6
Molecular Weight : 478.55
3-(3-(((3-Hydroxy-4-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 0241002
Molecular Weight : 454.57
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane
Catalogue No.:PA 09 0241000
3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-5-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 0241001
(S)-3-(3-(((3-Hydroxy-4-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 0241003
7,8-Dimethoxy-3-(3-(methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one Hydrochloride
Catalogue No.:PA 09 0241004
Molecular Formula : C16H25ClN2O3
Molecular Weight : 328.84
(S)-3-(3-(((3-Hydroxy-4-methoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one Hydrochloride
Catalogue No.:PA 09 0241005
Molecular Weight : 491.03
(S)-3-(3-(((4-Hydroxy-3-methoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one Hydrochloride
Catalogue No.:PA 09 0241006
3-(3-((2-(3,4-Dimethoxyphenyl)propyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one Hydrochloride
Catalogue No.:PA 09 0241007
Molecular Formula : C27H39ClN2O5
Molecular Weight : 507.07
3-(3-((((R)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxydecahydro-2H-benzo[d]azepin-2-one Hydrochloride
Catalogue No.:PA 09 0241009
Molecular Formula : C27H43ClN2O5
Molecular Weight : 511.1
2-Oxo-Ivabradine
Catalogue No.:PA 09 0241010
Dehydro Ivabradine Oxalate
Catalogue No.:PA 09 0241011
Molecular Formula : C29H36N2O9
Molecular Weight : 556.61
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