Glasdegib and its Impurities

Glasdegib, sold under the brand name Daurismo, is a medication for the treatment of newly-diagnosed acute myeloid leukemia in adults older than 75 years or those who have comorbidities that preclude use of intensive induction chemotherapy. Reference standards of Glasdegib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.