A COX-2 inhibitor, Etoricoxib is used in the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, spondylitis, chronic low back pain, and gout. It is a selective inhibitor of isoform 2 of the enzyme cyclooxygenase. Reference standards of Etoricoxib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Etoricoxib
Catalogue No.:PA 05 40000
CAS :
Molecular Formula : C18H15ClN2O2S
Molecular Weight : 358.84
2-Chloro-3-(dimethylamino)-N,N-dimethyl-2-propen-1-aminium Hexafluorophosphate(1-)
Catalogue No.:PA 05 40510
Molecular Formula : C7H14ClF6N2P
Molecular Weight : 306.62
2-Chloro-3-(dimethylamino)prop-2-en-1-iminiumchloride
Catalogue No.:PA 05 40530
Molecular Formula : C5H10Cl2N2
Molecular Weight : 169.05
2-(4-Methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-ethanone
Catalogue No.:PA 05 40540
Molecular Formula : C15H15NO3S
Molecular Weight : 289.35
Methyl 6-Methylnicotinate
Catalogue No.:PA 05 40550
Molecular Formula : C8H9NO2
Molecular Weight : 151.16
4-(Methylsulfonyl)acetophenone
Catalogue No.:PA 05 40570
Molecular Formula : C9H10O3S
Molecular Weight : 198.24
4-(Methylsulfonyl)phenylacetic Acid
Catalogue No.:PA 05 40580
Molecular Formula : C9H10O4S
Molecular Weight : 214.24
6'-Desmethyl-6'-carboxy Etoricoxib
Catalogue No.:PA 05 40590
Molecular Formula : C18H13ClN2O4S
Molecular Weight : 388.82
Etoricoxib N1'-Oxide
Catalogue No.:PA 05 40600
Molecular Formula : C18H15ClN2O3S
Molecular Weight : 374.84
1-(6-Methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethan-1-one oxime
Catalogue No.:PA 05 40610
Molecular Formula : C15H16N2O3S
Molecular Weight : 304.36
Desmethyl Etoricoxib
Catalogue No.:PA 05 40620
Molecular Formula : C17H13ClN2O2S
Molecular Weight : 344.82
2-Chloro-1,3-bis(dimethylamino)trimethinium hexafluorophosphate
Catalogue No.:PA 05 40640
6-Chloro-2-(6-methyl-3-pyridinyl)-3-[4-(methylsulfonyl)phenyl]-1,8-naphthyridine
Catalogue No.:PA 05 40650
Molecular Formula : C21H16ClN3O2S
Molecular Weight : 409.89
2-Chloroacetamide
Catalogue No.:PA 05 40660
Molecular Formula : C2H4ClNO
Molecular Weight : 93.51
(Z)-3-Amino-2-chloroacrylaldehyde
Catalogue No.:PA 05 40520
Molecular Formula : C3H4ClNO
Molecular Weight : 105.52
6'-Desmethyl-6'-methylhydroxy Etoricoxib
Catalogue No.:PA 05 40560
5-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfinylphenyl)pyridine
Catalogue No.:PA 05 40630
Molecular Formula : C18H15ClN2OS
Molecular Weight : 342.84
N,N,6'-Trimethyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridin]-5-amine
Catalogue No.:PA 05 40670
Molecular Formula : C20H21N3O2S
Molecular Weight : 367.46
2-(4-Methanesulfonylphenyl)-1-pyridin-3-ylethanone
Catalogue No.:PA 05 40680
Molecular Formula : C14H13NO3S
Molecular Weight : 275.32
Etoricoxib-d3
Catalogue No.:PA STI 040340
Molecular Formula : C18H12D3ClN2O2S
Molecular Weight : 361.86
Etoricoxib-d5
Catalogue No.:PA STI 040350
Molecular Formula : C18H10D5ClN2O2S
Molecular Weight : 363.87
Etoricoxib-d6
Catalogue No.:PA STI 040351
Molecular Formula : C18H9D6ClN2O2S
Molecular Weight : 364.88
Etoricoxib-13C,d3
Catalogue No.:PA STI 040360
Molecular Formula : C1713CH12D3ClN2O2S
Molecular Weight : 362.85
(Z)-2-Chloro-3-imino-N,N-dimethylprop-1-en-1-amine Hydrochloride
Catalogue No.:PAI 05 002510
Molecular Weight : 132.05
Catalogue No.:PA IPIPRS 65 13
Molecular Formula :
Molecular Weight : NA
Etoricoxib Related Compound A (1268874)
Catalogue No.:PA USP1268874
Molecular Formula : NA
Etoricoxib Related Compound B (1268885)
Catalogue No.:PA USP1268885
Etoricoxib Related Compound C (2-chloro-1,3-bis(dimethylamino)trimethinium hexafluorophosphate) (1268896)
Catalogue No.:PA USP1268896
2-Methyl-5-(3-(4-(methylsulfonyl)phenyl)furan-2-yl)pyridine
Catalogue No.:PA 05 40690
Molecular Formula : C17H15NO3S
Molecular Weight : 313.37
5,14-Dehydro Etoricoxib
Catalogue No.:PA 05 0401000
Molecular Formula : C18H13ClN2O2S
Molecular Weight : 356.82
2-(4-(Methylthio)phenyl)-1-(pyridin-3-yl)ethan-1-one
Catalogue No.:PAI 05 002511
Molecular Formula : C14H13NOS
Molecular Weight : 243.32
5-Chloro-3-(4-(methylthio)phenyl)-2,3'-bipyridine
Catalogue No.:PAI 05 002512
Molecular Formula : C17H13ClN2S
Molecular Weight : 312.82
Ethyl (4-methylthiophenyl)acetate
Catalogue No.:PAI 05 002513
Molecular Formula : C11H14O2S
Molecular Weight : 210.29
1-(6-Methylpyridin-3-yl)-2-(4-(methylsulfinyl)phenyl)ethan-1-one
Catalogue No.:PA 05 0401001
Molecular Formula : C15H15NO2S
Molecular Weight : 273.35
1-(6-Methylpyridin-3-yl)-2-(4-(methylthio)phenyl)ethan-1-one
Catalogue No.:PA 05 0401002
Molecular Formula : C15H15NOS
Molecular Weight : 257.35
1-(6-Methylpyridin-3-yl)-2-((4-(2-(6-methylpyridin-3-yl)-2-oxoethyl)phenyl)sulfonyl)ethan-1-one
Catalogue No.:PA 05 0401003
Molecular Formula : C22H20N2O4S
Molecular Weight : 408.47
Etoricoxib D4
Catalogue No.:PA STI 088697
Molecular Formula : C18H11D4ClN2O2S
Molecular Weight : 362.86
Catalogue No.:PA IPRS 61 19
6'-Methyl-3-(4-(methylsulfonyl)phenyl)-2,3'-bipyridine
Catalogue No.:PA 05 0401004
Molecular Formula : C18H16N2O2S
Molecular Weight : 324.4
6,6''-Dimethyl-3',5'-bis(4-(methylsulfonyl)phenyl)-3,2':6',3''-terpyridine;
Catalogue No.:PA 05 0401005
Molecular Formula : C31H27N3O4S2
Molecular Weight : 569.69
2-(4-(Methylsulfonyl)phenyl)-1-morpholinoethan-1-one
Catalogue No.:PA 05 0401006
Molecular Formula : C13H17NO4S
Molecular Weight : 283.34
2-Methyl-5-(2-(4-(methylsulfonyl)phenyl)acetyl)pyridine 1-oxide
Catalogue No.:PA 05 0401007
Molecular Formula : C15H15NO4S
Molecular Weight : 305.35
(E)-5-(1,3-bis(4-(Methylsulfonyl)phenyl)prop-1-en-2-yl)-2-methylpyridine
Catalogue No.:PA 05 0401008
Molecular Formula : C23H23NO4S2
Molecular Weight : 441.56
4-Chloro-5-(dimethylamino)-1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)penta-2,4-dien-1-one
Catalogue No.:PA 05 0401009
Molecular Formula : C20H21ClN2O3S
Molecular Weight : 404.91
5-Chloro-6'-methyl-3-(4-(methylthio)phenyl)-2,3'-bipyridine
Catalogue No.:PA 05 0401010
Molecular Formula : C18H15ClN2S
Molecular Weight : 326.84
2-((4-(5-Chloro-6'-methyl-[2,3'-bipyridin]-3-yl)phenyl)sulfonyl)-1-(6-methylpyridin-3-yl)ethan-1-one
Catalogue No.:PA 05 0401011
Molecular Formula : C25H20ClN3O3S
Molecular Weight : 477.96
5-Chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridine] 1-oxide
Catalogue No.:PA 05 0401012
6'-Methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridin]-5-amine
Catalogue No.:PA 05 0401013
Molecular Formula : C18H17N3O2S
Molecular Weight : 339.41
2-((4-(5-Chloro-6'-methyl-[2,3'-bipyridin]-3-yl)phenyl)sulfonyl)-1-(4-(methylsulfonyl)phenyl)ethan-1-ol
Catalogue No.:PA 05 0401014
Molecular Formula : C26H23ClN2O5S2
Molecular Weight : 543.05
2-(5-Chloro-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridin]-6'-yl)-1-(6-(methylsulfonyl)pyridin-3-yl)ethan-1-ol
Catalogue No.:PA 05 0401015
Molecular Formula : C25H22ClN3O5S
Molecular Weight : 544.04
2-(5-Chloro-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridin]-6'-yl)-1-(6-methylpyridin-3-yl)ethan-1-ol
Catalogue No.:PA 05 0401016
Molecular Formula : C25H22ClN3O3S
Molecular Weight : 479.98
5-(5'-Chloro-4,4''-bis(methylsulfonyl)-[1,1':3',1''-terphenyl]-2'-yl)-2-methylpyridine
Catalogue No.:PA 05 0401017
Molecular Formula : C26H22ClNO4S2
Molecular Weight : 512.04
5-Chloro-6′-(methylsulfonyl)-3-[4-(methylsulfonyl)phenyl]-2,3′-bipyridine
Catalogue No.:PA 05 0401018
Molecular Formula : C18H15ClN2O4S2
Molecular Weight : 422.9
5-Chloro-3-(4-(ethylsulfonyl)phenyl)-6'-methyl-2,3'-bipyridine
Catalogue No.:PA 05 0401019
Molecular Formula : C19H17ClN2O2S
Molecular Weight : 372.87
2-(4-(Methylthio)phenyl)acetonitrile
Catalogue No.:PA 05 0401020
Molecular Formula : C9H9NS
Molecular Weight : 163.24
3-(6-Methylpyridin-3-yl)-2-(4-(methylthio)phenyl)-3-oxopropanenitrile
Catalogue No.:PA 05 0401021
Molecular Formula : C16H14N2OS
Molecular Weight : 282.36
1-(6-Methylpyridin-3-yl)-2-(2-(methylsulfonyl)phenyl)ethan-1-one
Catalogue No.:PA 05 0401022
1-(4-(Methylsulfinyl)phenyl)ethan-1-one
Catalogue No.:PA 05 0401023
Molecular Formula : C9H10O2S
Molecular Weight : 182.24
2-(4-(Methylsulfonyl)phenyl)-1-morpholinoethane-1-thione
Catalogue No.:PA 05 0401024
Molecular Formula : C13H17NO3S2
Molecular Weight : 299.4
3-Hydroxy-3-(6-methylpyridin-3-yl)-2,4-bis(4-(methylsulfonyl)phenyl)butanoic Acid
Catalogue No.:PA 05 0401025
Molecular Formula : C24H25NO7S2
Molecular Weight : 503.58
(E)-1-(6-Methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethan-1-one oxime
Catalogue No.:PA 05 0401026
Methyl 6-methylnicotinate
Catalogue No.:PA BSC 04005376
Molecular Weight : 151.17
Etoricoxib (IPRSE043)
Catalogue No.:PA IPRSE043
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