Etelcalcetide Hydrochloride and its Impurities

Etelcalcetide Hydrochloride is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease. Reference standards of Etelcalcetide Hydrochloride API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.