Eltrombopag Choline and its Impurities

Eltrombopag Choline is used to treat low blood platelet counts in adults with chronic immune thrombocytopenia when certain other medicines, or surgery to remove the spleen, have not worked well enough. It has been recently approved for the treatment of thrombocytopenia in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy. Reference standards of Eltrombopag Choline API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.