Elexacaftor is a small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation. Reference standards of Elexacaftor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Elexacaftor
Catalogue No.:PA 05 1861000
CAS :
Molecular Formula : C26H34F3N7O4S
Molecular Weight : 597.66
2-Chloro-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)nicotinamide
Catalogue No.:PA 05 1861001
Molecular Formula : C19H20ClF3N6O4S
Molecular Weight : 520.91
N-Desmethyl Elexacaftor
Catalogue No.:PA 05 1861002
Molecular Formula : C25H32F3N7O4S
Molecular Weight : 583.63
(R)-Elexacaftor
Catalogue No.:PA 05 1861003
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