Eflornithine Hydrochloride and its Impurities

Eflornithine Hydrochloride, sold under the brand name Vaniqa among others, is a medication used to treat African trypanosomiasis (sleeping sickness) and excessive hair growth on the face in women. Specifically it is used for the 2nd stage of sleeping sickness caused by T. b. gambiense and may be used with nifurtimox.It is used by injection or applied to the skin. Reference standards of Eflornithine Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.