Diphenhydramine-impurities | Pharmaffiliates

diphenhydramine and its Impurities

Diphenhydramine is a first-generation antihistamine used to treat a number of conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms. It can also be used for insomnia, symptoms of the common cold, tremor in parkinsonism, and nausea.. Reference standards of Diphenhydramine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 34 results for diphenhydramine Impurities
PA 04 31010

Diphenhydramine - Impurity A

N-Desmethyl Diphenhydramine Hydrochloride


  • Catalogue No.:PA 04 31010

  • CAS :

    53499-40-4

  • Molecular Formula : C16H20ClNO

  • Molecular Weight : 277.79

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PA 04 31020

Diphenhydramine - Impurity B

4-Methyldiphenhydramine Hydrochloride


  • Catalogue No.:PA 04 31020

  • CAS :

    4024-34-4

  • Molecular Formula : C18H24ClNO

  • Molecular Weight : 305.84

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PA 04 31030

Diphenhydramine - Impurity C (Hydrochloride Salt)

Bromazine Hydrochloride


  • Catalogue No.:PA 04 31030

  • CAS :

    1808-12-4

  • Molecular Formula : C17H21BrClNO

  • Molecular Weight : 370.71

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PA 04 31040

Diphenhydramine - Impurity D

Benzhydrol


  • Catalogue No.:PA 04 31040

  • CAS :

    91-01-0

  • Molecular Formula : C13H12O

  • Molecular Weight : 184.23

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PA 04 31050

Diphenhydramine - Impurity E (Freebase)

Benzophenone


  • Catalogue No.:PA 04 31050

  • CAS :

    119-61-9

  • Molecular Formula : C13H10O

  • Molecular Weight : 182.22

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PA 04 31510

Diphenhydramine N-Oxide

Diphenhydramine N-Oxide


  • Catalogue No.:PA 04 31510

  • CAS :

    3922-74-5

  • Molecular Formula : C17H21NO2

  • Molecular Weight : 271.35

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PA 04 0311000

3-(Diphenylmethoxy)-1,2-propanediol

3-(Diphenylmethoxy)-1,2-propanediol


  • Catalogue No.:PA 04 0311000

  • CAS :

    19574-66-4

  • Molecular Formula : C16H18O3

  • Molecular Weight : 258.32

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PA 04 31021

Diphenhydramine - Impurity B

2-[(RS)-(4-methylphenyl)phenylmethoxy]-N,N-dimethylethanamine


  • Catalogue No.:PA 04 31021

  • CAS :

    19804-27-4

  • Molecular Formula : C18H23NO

  • Molecular Weight : 269.39

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PA 31 57000

Diphenhydramine - API Standards

Diphenhydramine


  • Catalogue No.:PA 31 57000

  • CAS :

    58-73-1

  • Molecular Formula : C17H21NO

  • Molecular Weight : 255.35

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PA 04 31520

2-(Diphenylmethoxy)-N,N,N-trimethylethanaminium Bromide

2-(Diphenylmethoxy)-N,N,N-trimethylethanaminium Bromide


  • Catalogue No.:PA 04 31520

  • CAS :

    31065-89-1

  • Molecular Formula : C18H24BrNO

  • Molecular Weight : 350.29

PA 04 31530

Diphenhydramine N-Oxide Hydrochloride

Diphenhydramine N-Oxide Hydrochloride


  • Catalogue No.:PA 04 31530

  • CAS :

    13168-00-8

  • Molecular Formula : C17H22ClNO2

  • Molecular Weight : 307.82

PA 04 31540

2-(Benzhydryloxy)-N-methylacetamide

2-(Benzhydryloxy)-N-methylacetamide


  • Catalogue No.:PA 04 31540

  • CAS :

    118286-16-1

  • Molecular Formula : C16H17NO2

  • Molecular Weight : 255.31

PA 04 31550

Diphenhydramine Citrate - API Standards

Diphenhydramine Citrate


  • Catalogue No.:PA 04 31550

  • CAS :

    88637-37-0

  • Molecular Formula : C23H29NO8

  • Molecular Weight : 447.48

PA STI 028280

N-Desmethyl Diphenhydramine-d3 Hydrochloride

N-Desmethyl Diphenhydramine-d3 Hydrochloride


  • Catalogue No.:PA STI 028280

  • CAS :

    1794759-12-8

  • Molecular Formula : C16H17D3ClNO

  • Molecular Weight : 280.81

PA STI 035500

Diphenhydramine-d6 N-β-D-Glucuronide

Diphenhydramine-d6 N-β-D-Glucuronide


  • Catalogue No.:PA STI 035500

  • CAS :

    NA

  • Molecular Formula : C23H23D6NO7

  • Molecular Weight : 437.52

PA STI 035510

Diphenhydramine-d6 N-Oxide

Diphenhydramine-d6 N-Oxide


  • Catalogue No.:PA STI 035510

  • CAS :

    1346603-42-6

  • Molecular Formula : C17H15D6NO2

  • Molecular Weight : 277.39

PA USP1077005

Bromodiphenhydramine Hydrochloride (1077005)

Bromodiphenhydramine Hydrochloride (1077005)


  • Catalogue No.:PA USP1077005

  • CAS :

    1808-12-4

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1218050

Diphenhydramine N-Oxide (2-(benzhydryloxy)-N,N-dimethylethan-1-amine oxide hydrochloride) (1218050)

Diphenhydramine N-Oxide (2-(benzhydryloxy)-N,N-dimethylethan-1-amine oxide hydrochloride) (1218050)


  • Catalogue No.:PA USP1218050

  • CAS :

    13168-00-8

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1218005

Diphenhydramine Hydrochloride (1218005)

Diphenhydramine Hydrochloride (1218005)


  • Catalogue No.:PA USP1218005

  • CAS :

    147-24-0

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1218027

Diphenhydramine Related Compound B (3-(benzhydryloxy)propane-1,2-diol) (1218027)

Diphenhydramine Related Compound B (3-(benzhydryloxy)propane-1,2-diol) (1218027)


  • Catalogue No.:PA USP1218027

  • CAS :

    19574-66-4

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1218016

Diphenhydramine Related Compound A (2-(Diphenylmethoxy)-N-methylethanamine hydrochloride) (1218016)

Diphenhydramine Related Compound A (2-(Diphenylmethoxy)-N-methylethanamine hydrochloride) (1218016)


  • Catalogue No.:PA USP1218016

  • CAS :

    53499-40-4

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1217909

Diphenhydramine Citrate (1217909)

Diphenhydramine Citrate (1217909)


  • Catalogue No.:PA USP1217909

  • CAS :

    88637-37-0

  • Molecular Formula : NA

  • Molecular Weight : NA

PA BP896RB

diphenhydramine hydrochloride (896RB)

diphenhydramine hydrochloride (896RB)


  • Catalogue No.:PA BP896RB

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA IPIPRS 26 11

Diphenhydramine Hydrochloride (IPRS/26/11)-from IPC


  • Catalogue No.:PA IPIPRS 26 11

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA STI 088325

Diphenhydramine-d5 HCl (phenyl-d5)

Diphenhydramine-d5 HCl (phenyl-d5)


  • Catalogue No.:PA STI 088325

  • CAS :

    1219795-16-0

  • Molecular Formula : C17H17D5ClNO

  • Molecular Weight : 296.85

PA 04 31031

Diphenhydramine - Impurity C

2-[(RS)-(4-Bromophenyl)phenylmethoxy]-N,N-dimethylethanamine


  • Catalogue No.:PA 04 31031

  • CAS :

    118-23-0

  • Molecular Formula : C17H20BrNO

  • Molecular Weight : 334.26

PA 31 0571000

2-Chloro(methylphenyl)phenylmethoxy Ethane Ether

2-Chloro(methylphenyl)phenylmethoxy Ethane Ether


  • Catalogue No.:PA 31 0571000

  • CAS :

    22135-59-7

  • Molecular Formula : C16H17ClO

  • Molecular Weight : 260.76

PA 31 0571001

Benzhydryl Bromide

Benzhydryl Bromide


  • Catalogue No.:PA 31 0571001

  • CAS :

    776-74-9

  • Molecular Formula : C13H11Br

  • Molecular Weight : 247.14

PA 31 0571002

Benzeneacetic acid, a-methyl-4-(1-methylethyl)-

Benzeneacetic acid, a-methyl-4-(1-methylethyl)-


  • Catalogue No.:PA 31 0571002

  • CAS :

    3585-48-6

  • Molecular Formula : C12H16O2

  • Molecular Weight : 192.26

PA 31 0571003

4,4-Bis(diethylamino)benzophenone

4,4-Bis(diethylamino)benzophenone


  • Catalogue No.:PA 31 0571003

  • CAS :

    90-93-7

  • Molecular Formula : C21H28N2O

  • Molecular Weight : 324.47

PA STI 089547

N-Nitroso N-Desmethyl Diphenhydramine-D5

N-Nitroso N-Desmethyl Diphenhydramine-D5


  • Catalogue No.:PA STI 089547

  • CAS :

    NA

  • Molecular Formula : C16H13D5N2O2

  • Molecular Weight : 275.36

PA 31 0571004

Diphenhydramine N-glucuronide

Diphenhydramine N-glucuronide


  • Catalogue No.:PA 31 0571004

  • CAS :

    137908-78-2

  • Molecular Formula : C23H29NO7

  • Molecular Weight : 431.49

PA STI 089733

Diphenhydramine-d3 Dimer

Diphenhydramine-d3 Dimer


  • Catalogue No.:PA STI 089733

  • CAS :

    NA

  • Molecular Formula : C31H30D3NO2

  • Molecular Weight : 454.63

PA IMP 25 18

Diphenhydramine Impurity -A (IMP/25/18)

Diphenhydramine Impurity -A (IMP/25/18)


  • Catalogue No.:PA IMP 25 18

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA